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Predictors of Failure of Percutaneous Coronary Intervention in Patients with Chronic Total Coronary Occlusion at National Cardiovascular Center Indonesia

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Title: Predictors of Failure of Percutaneous Coronary Intervention in Patients with Chronic Total Coronary Occlusion at National Cardiovascular Center Indonesia
Authors: I Gumiwang, Muhammad Munawar, RWM Kaligis
Source: Majalah Kardiologi Indonesia, Vol 28, Iss 1 (2007)
Publisher Information: Indonesian Heart Association, 2007.
Publication Year: 2007
Collection: LCC:Diseases of the circulatory (Cardiovascular) system
Subject Terms: Ischemia Modified Albumin (IMA), percutaneous coronary angioplasty variables of PCI, Diseases of the circulatory (Cardiovascular) system, RC666-701
More Details: Background. Percutaneous Coronary Intervention (PCI) in patients with Chronic Total Coronary Occlusion (CTO) is associated with higher rate of failure and higher rate of complication compared to non-CTO angioplasty. Improvement in technique, logistic and patients selection method lead to a better success rate. Identification of predictor of failure could be an important step in patient selection. The aim of the study is to know the predictors of failure of PCI in patients with CTO. Methods and results. A retrospective analysis of clinical and angiographic data of 78 consecutive eligible CTO patients who underwent PCI selected in series of 1205 total occluded vessel of 3654 angiographic patients in the year of 2005 in our catheterization laboratory. We analysed 25 variables, 12 clinical variables (age, sex, family history, smoking, diabetes mellitus, hypertension, history of myiocardial infarction, history of coronary bypass operation, age of occlusion >1 year, severe angina and poor left ventricle systolic dysfunction)and 13 angiographic variables (true CTO, CTO location, ostial lesion, calcification, tortousity, non-tapered type, side branch type, bridging collateral, diffuse disease, vessel diameter < 3mm, CTO length > 15mm, multi-lesion and multi vessel disease)by univariate and multivariate analysis (logistic regression) in association between 21 cases of procedural failure group and 57 cases of procedural success group. Procedural success was achieved in 57 patients (73%) and complication occured in one patient (1%). Majority of patients are male with mean age 55 year. Presence of calcification is the only predictor identified by univariate analysis (OR 3,28. p 0,04. 95%CI 1.05-10,18). Multivariate analysis identified multivessel disease (OR 7,1. p 0,07 .95%CI 0,85-59,21) and diffuse disease (OR 2,7. p 0,06 .95%CI 0,93-8,08) as predictors of procedural failure. Conclusions. We identified multivessel disease and diffuse disease as two predictors of procedural failure of PCI in our series of CTO patients with 73% success rate and 1% complication rate in the year of 2005.
Document Type: article
File Description: electronic resource
Language: English
Indonesian
ISSN: 0126-3773
2620-4762
Relation: http://ijconline.id/index.php/ijc/article/view/266; https://doaj.org/toc/0126-3773; https://doaj.org/toc/2620-4762
DOI: 10.30701/ijc.v28i1.266
Access URL: https://doaj.org/article/cdde7d8710ea4cf08ecc827f12e76a5f
Accession Number: edsdoj.7d8710ea4cf08ecc827f12e76a5f
Database: Directory of Open Access Journals
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  Data: Background. Percutaneous Coronary Intervention (PCI) in patients with Chronic Total Coronary Occlusion (CTO) is associated with higher rate of failure and higher rate of complication compared to non-CTO angioplasty. Improvement in technique, logistic and patients selection method lead to a better success rate. Identification of predictor of failure could be an important step in patient selection. The aim of the study is to know the predictors of failure of PCI in patients with CTO. Methods and results. A retrospective analysis of clinical and angiographic data of 78 consecutive eligible CTO patients who underwent PCI selected in series of 1205 total occluded vessel of 3654 angiographic patients in the year of 2005 in our catheterization laboratory. We analysed 25 variables, 12 clinical variables (age, sex, family history, smoking, diabetes mellitus, hypertension, history of myiocardial infarction, history of coronary bypass operation, age of occlusion &gt;1 year, severe angina and poor left ventricle systolic dysfunction)and 13 angiographic variables (true CTO, CTO location, ostial lesion, calcification, tortousity, non-tapered type, side branch type, bridging collateral, diffuse disease, vessel diameter &lt; 3mm, CTO length &gt; 15mm, multi-lesion and multi vessel disease)by univariate and multivariate analysis (logistic regression) in association between 21 cases of procedural failure group and 57 cases of procedural success group. Procedural success was achieved in 57 patients (73%) and complication occured in one patient (1%). Majority of patients are male with mean age 55 year. Presence of calcification is the only predictor identified by univariate analysis (OR 3,28. p 0,04. 95%CI 1.05-10,18). Multivariate analysis identified multivessel disease (OR 7,1. p 0,07 .95%CI 0,85-59,21) and diffuse disease (OR 2,7. p 0,06 .95%CI 0,93-8,08) as predictors of procedural failure. Conclusions. We identified multivessel disease and diffuse disease as two predictors of procedural failure of PCI in our series of CTO patients with 73% success rate and 1% complication rate in the year of 2005.
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      – Text: English
      – Text: Indonesian
    Subjects:
      – SubjectFull: Ischemia Modified Albumin (IMA)
        Type: general
      – SubjectFull: percutaneous coronary angioplasty variables of PCI
        Type: general
      – SubjectFull: Diseases of the circulatory (Cardiovascular) system
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      – TitleFull: Predictors of Failure of Percutaneous Coronary Intervention in Patients with Chronic Total Coronary Occlusion at National Cardiovascular Center Indonesia
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            NameFull: I Gumiwang
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            NameFull: Muhammad Munawar
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