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Drug Monitoring by Optically Pumped Atomic Magnetometer

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Title: Drug Monitoring by Optically Pumped Atomic Magnetometer
Authors: Yi Ruan, Xiang He, Limeng Ruan, Fan Liu, Zhiwen Zhang, Jiaqi Weng, Qinying Yan, Guoyi Zhang, Kan Li, Wenqiang Zheng, Qiang Lin
Source: IEEE Photonics Journal, Vol 14, Iss 4, Pp 1-5 (2022)
Publisher Information: IEEE, 2022.
Publication Year: 2022
Collection: LCC:Applied optics. Photonics
LCC:Optics. Light
Subject Terms: Atomic magnetometer, drug monitoring, magnetic nanoparticle, Applied optics. Photonics, TA1501-1820, Optics. Light, QC350-467
More Details: A novel drug monitoring method is experimentally demonstrated by optically pumped atomic magnetometer. An elliptically polarized single-beam spin-exchange-relaxation-free atomic magnetometer (SERF AM) is used to realize magnetorelaxometry (MRX) measurement and thereby quantify concentrations of superparamagnetic nanoparticles in solutions. Moreover, drug-conjugated magnetic nanoparticles are monitored in mice for twelve hours to study the drug sustained-release mechanism. Our results show the great potential of optically pumped atomic magnetometer for application in biophysical, pharmaceutical and medical areas, and may promote fields such as drug delivery research, virus detection, and molecule quantification.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1943-0655
Relation: https://ieeexplore.ieee.org/document/9799754/; https://doaj.org/toc/1943-0655
DOI: 10.1109/JPHOT.2022.3184050
Access URL: https://doaj.org/article/7ccb3fa57278428985356b172390fbd2
Accession Number: edsdoj.7ccb3fa57278428985356b172390fbd2
Database: Directory of Open Access Journals
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  Data: Drug Monitoring by Optically Pumped Atomic Magnetometer
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  Data: <searchLink fieldCode="AR" term="%22Yi+Ruan%22">Yi Ruan</searchLink><br /><searchLink fieldCode="AR" term="%22Xiang+He%22">Xiang He</searchLink><br /><searchLink fieldCode="AR" term="%22Limeng+Ruan%22">Limeng Ruan</searchLink><br /><searchLink fieldCode="AR" term="%22Fan+Liu%22">Fan Liu</searchLink><br /><searchLink fieldCode="AR" term="%22Zhiwen+Zhang%22">Zhiwen Zhang</searchLink><br /><searchLink fieldCode="AR" term="%22Jiaqi+Weng%22">Jiaqi Weng</searchLink><br /><searchLink fieldCode="AR" term="%22Qinying+Yan%22">Qinying Yan</searchLink><br /><searchLink fieldCode="AR" term="%22Guoyi+Zhang%22">Guoyi Zhang</searchLink><br /><searchLink fieldCode="AR" term="%22Kan+Li%22">Kan Li</searchLink><br /><searchLink fieldCode="AR" term="%22Wenqiang+Zheng%22">Wenqiang Zheng</searchLink><br /><searchLink fieldCode="AR" term="%22Qiang+Lin%22">Qiang Lin</searchLink>
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  Data: IEEE Photonics Journal, Vol 14, Iss 4, Pp 1-5 (2022)
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  Data: IEEE, 2022.
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  Data: 2022
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  Data: LCC:Applied optics. Photonics<br />LCC:Optics. Light
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  Data: <searchLink fieldCode="DE" term="%22Atomic+magnetometer%22">Atomic magnetometer</searchLink><br /><searchLink fieldCode="DE" term="%22drug+monitoring%22">drug monitoring</searchLink><br /><searchLink fieldCode="DE" term="%22magnetic+nanoparticle%22">magnetic nanoparticle</searchLink><br /><searchLink fieldCode="DE" term="%22Applied+optics%2E+Photonics%22">Applied optics. Photonics</searchLink><br /><searchLink fieldCode="DE" term="%22TA1501-1820%22">TA1501-1820</searchLink><br /><searchLink fieldCode="DE" term="%22Optics%2E+Light%22">Optics. Light</searchLink><br /><searchLink fieldCode="DE" term="%22QC350-467%22">QC350-467</searchLink>
– Name: Abstract
  Label: Description
  Group: Ab
  Data: A novel drug monitoring method is experimentally demonstrated by optically pumped atomic magnetometer. An elliptically polarized single-beam spin-exchange-relaxation-free atomic magnetometer (SERF AM) is used to realize magnetorelaxometry (MRX) measurement and thereby quantify concentrations of superparamagnetic nanoparticles in solutions. Moreover, drug-conjugated magnetic nanoparticles are monitored in mice for twelve hours to study the drug sustained-release mechanism. Our results show the great potential of optically pumped atomic magnetometer for application in biophysical, pharmaceutical and medical areas, and may promote fields such as drug delivery research, virus detection, and molecule quantification.
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  Data: https://ieeexplore.ieee.org/document/9799754/; https://doaj.org/toc/1943-0655
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  Data: 10.1109/JPHOT.2022.3184050
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      – SubjectFull: Atomic magnetometer
        Type: general
      – SubjectFull: drug monitoring
        Type: general
      – SubjectFull: magnetic nanoparticle
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      – SubjectFull: Applied optics. Photonics
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