Academic Journal
View in EDS
Linked Full Text

Association between psychotropics use and occurrence of falls in hospitalized patients: A matched case–control study

Bibliographic Details
Title: Association between psychotropics use and occurrence of falls in hospitalized patients: A matched case–control study
Authors: Chihiro Morishita, Jiro Masuya, Yoshitaka Ishii, Tomoteru Seki, Ayaka Deguchi, Yoshio Iwata, Yu Tamada, Yota Fujimura, Mina Honyashiki, Kazuharu Harada, Masataka Taguri, Takeshi Inoue
Source: PCN Reports, Vol 2, Iss 3, Pp n/a-n/a (2023)
Publisher Information: Wiley, 2023.
Publication Year: 2023
Collection: LCC:Psychiatry
Subject Terms: falls, hospitalized patients, matched case–control study, psychotropics, risk factor, Psychiatry, RC435-571
More Details: Abstract Aim Understanding the appropriate prescription of psychotropics for hospitalized patients in terms of preventing falls is an important issue. The aim of this study was to assess the associations between the occurrence of falls and the use of various individual psychotropics in hospitalized patients. Methods A retrospective matched case–control study was conducted on adult patients admitted to every department of Tokyo Medical University Hospital, with the outcome being in‐hospital falls. A total of 447 hospitalized patients who had had in‐hospital falls at some point in their hospitalization between January 2016 and December 2016 were included as cases. A total of 447 hospitalized patients who did not have in‐hospital falls, and were individually matched to the cases by sex, age, and clinical department, were included as controls. All data were extracted from electronic medical records. Conditional logistic regression analyses were conducted to assess the association between the exposure to 16 psychotropic medications and the occurrence of in‐hospital falls. The multivariable logistic regression model adjusted sex, age, clinical department, body mass index, fall risk score on the fall risk assessment measure, and use of psychotropic medications. Results The multivariable conditional logistic regression model showed a significant association between the use of risperidone (odds ratio [OR] = 3.730; 95% confidence interval [CI] = 1.229–11.325) and flunitrazepam (OR = 4.120; 95% CI = 1.105–15.364) and an increased OR of falls among hospitalized patients. Conclusion The use of risperidone and flunitrazepam were identified as risk factors for falls among hospitalized patients.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2769-2558
Relation: https://doaj.org/toc/2769-2558
DOI: 10.1002/pcn5.133
Access URL: https://doaj.org/article/5b80ff4e9bfc47f28ca477310a84063c
Accession Number: edsdoj.5b80ff4e9bfc47f28ca477310a84063c
Database: Directory of Open Access Journals
FullText Links:
  – Type: other
    Url: https://resolver.ebsco.com:443/public/rma-ftfapi/ejs/direct?AccessToken=4C20982C37CEB7A5D613&Show=Object
Text:
  Availability: 0
CustomLinks:
  – Url: https://resolver.ebsco.com/c/xy5jbn/result?sid=EBSCO:edsdoj&genre=article&issn=27692558&ISBN=&volume=2&issue=3&date=20230901&spage=&pages=&title=PCN Reports&atitle=Association%20between%20psychotropics%20use%20and%20occurrence%20of%20falls%20in%20hospitalized%20patients%3A%20A%20matched%20case%E2%80%93control%20study&aulast=Chihiro%20Morishita&id=DOI:10.1002/pcn5.133
    Name: Full Text Finder (for New FTF UI) (s8985755)
    Category: fullText
    Text: Find It @ SCU Libraries
    MouseOverText: Find It @ SCU Libraries
  – Url: https://doaj.org/article/5b80ff4e9bfc47f28ca477310a84063c
    Name: EDS - DOAJ (s8985755)
    Category: fullText
    Text: View record from DOAJ
    MouseOverText: View record from DOAJ
Header DbId: edsdoj
DbLabel: Directory of Open Access Journals
An: edsdoj.5b80ff4e9bfc47f28ca477310a84063c
RelevancyScore: 975
AccessLevel: 3
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 975.256042480469
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Association between psychotropics use and occurrence of falls in hospitalized patients: A matched case–control study
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Chihiro+Morishita%22">Chihiro Morishita</searchLink><br /><searchLink fieldCode="AR" term="%22Jiro+Masuya%22">Jiro Masuya</searchLink><br /><searchLink fieldCode="AR" term="%22Yoshitaka+Ishii%22">Yoshitaka Ishii</searchLink><br /><searchLink fieldCode="AR" term="%22Tomoteru+Seki%22">Tomoteru Seki</searchLink><br /><searchLink fieldCode="AR" term="%22Ayaka+Deguchi%22">Ayaka Deguchi</searchLink><br /><searchLink fieldCode="AR" term="%22Yoshio+Iwata%22">Yoshio Iwata</searchLink><br /><searchLink fieldCode="AR" term="%22Yu+Tamada%22">Yu Tamada</searchLink><br /><searchLink fieldCode="AR" term="%22Yota+Fujimura%22">Yota Fujimura</searchLink><br /><searchLink fieldCode="AR" term="%22Mina+Honyashiki%22">Mina Honyashiki</searchLink><br /><searchLink fieldCode="AR" term="%22Kazuharu+Harada%22">Kazuharu Harada</searchLink><br /><searchLink fieldCode="AR" term="%22Masataka+Taguri%22">Masataka Taguri</searchLink><br /><searchLink fieldCode="AR" term="%22Takeshi+Inoue%22">Takeshi Inoue</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: PCN Reports, Vol 2, Iss 3, Pp n/a-n/a (2023)
– Name: Publisher
  Label: Publisher Information
  Group: PubInfo
  Data: Wiley, 2023.
– Name: DatePubCY
  Label: Publication Year
  Group: Date
  Data: 2023
– Name: Subset
  Label: Collection
  Group: HoldingsInfo
  Data: LCC:Psychiatry
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22falls%22">falls</searchLink><br /><searchLink fieldCode="DE" term="%22hospitalized+patients%22">hospitalized patients</searchLink><br /><searchLink fieldCode="DE" term="%22matched+case–control+study%22">matched case–control study</searchLink><br /><searchLink fieldCode="DE" term="%22psychotropics%22">psychotropics</searchLink><br /><searchLink fieldCode="DE" term="%22risk+factor%22">risk factor</searchLink><br /><searchLink fieldCode="DE" term="%22Psychiatry%22">Psychiatry</searchLink><br /><searchLink fieldCode="DE" term="%22RC435-571%22">RC435-571</searchLink>
– Name: Abstract
  Label: Description
  Group: Ab
  Data: Abstract Aim Understanding the appropriate prescription of psychotropics for hospitalized patients in terms of preventing falls is an important issue. The aim of this study was to assess the associations between the occurrence of falls and the use of various individual psychotropics in hospitalized patients. Methods A retrospective matched case–control study was conducted on adult patients admitted to every department of Tokyo Medical University Hospital, with the outcome being in‐hospital falls. A total of 447 hospitalized patients who had had in‐hospital falls at some point in their hospitalization between January 2016 and December 2016 were included as cases. A total of 447 hospitalized patients who did not have in‐hospital falls, and were individually matched to the cases by sex, age, and clinical department, were included as controls. All data were extracted from electronic medical records. Conditional logistic regression analyses were conducted to assess the association between the exposure to 16 psychotropic medications and the occurrence of in‐hospital falls. The multivariable logistic regression model adjusted sex, age, clinical department, body mass index, fall risk score on the fall risk assessment measure, and use of psychotropic medications. Results The multivariable conditional logistic regression model showed a significant association between the use of risperidone (odds ratio [OR] = 3.730; 95% confidence interval [CI] = 1.229–11.325) and flunitrazepam (OR = 4.120; 95% CI = 1.105–15.364) and an increased OR of falls among hospitalized patients. Conclusion The use of risperidone and flunitrazepam were identified as risk factors for falls among hospitalized patients.
– Name: TypeDocument
  Label: Document Type
  Group: TypDoc
  Data: article
– Name: Format
  Label: File Description
  Group: SrcInfo
  Data: electronic resource
– Name: Language
  Label: Language
  Group: Lang
  Data: English
– Name: ISSN
  Label: ISSN
  Group: ISSN
  Data: 2769-2558
– Name: NoteTitleSource
  Label: Relation
  Group: SrcInfo
  Data: https://doaj.org/toc/2769-2558
– Name: DOI
  Label: DOI
  Group: ID
  Data: 10.1002/pcn5.133
– Name: URL
  Label: Access URL
  Group: URL
  Data: <link linkTarget="URL" linkTerm="https://doaj.org/article/5b80ff4e9bfc47f28ca477310a84063c" linkWindow="_blank">https://doaj.org/article/5b80ff4e9bfc47f28ca477310a84063c</link>
– Name: AN
  Label: Accession Number
  Group: ID
  Data: edsdoj.5b80ff4e9bfc47f28ca477310a84063c
PLink https://login.libproxy.scu.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edsdoj&AN=edsdoj.5b80ff4e9bfc47f28ca477310a84063c
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1002/pcn5.133
    Languages:
      – Text: English
    Subjects:
      – SubjectFull: falls
        Type: general
      – SubjectFull: hospitalized patients
        Type: general
      – SubjectFull: matched case–control study
        Type: general
      – SubjectFull: psychotropics
        Type: general
      – SubjectFull: risk factor
        Type: general
      – SubjectFull: Psychiatry
        Type: general
      – SubjectFull: RC435-571
        Type: general
    Titles:
      – TitleFull: Association between psychotropics use and occurrence of falls in hospitalized patients: A matched case–control study
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Chihiro Morishita
      – PersonEntity:
          Name:
            NameFull: Jiro Masuya
      – PersonEntity:
          Name:
            NameFull: Yoshitaka Ishii
      – PersonEntity:
          Name:
            NameFull: Tomoteru Seki
      – PersonEntity:
          Name:
            NameFull: Ayaka Deguchi
      – PersonEntity:
          Name:
            NameFull: Yoshio Iwata
      – PersonEntity:
          Name:
            NameFull: Yu Tamada
      – PersonEntity:
          Name:
            NameFull: Yota Fujimura
      – PersonEntity:
          Name:
            NameFull: Mina Honyashiki
      – PersonEntity:
          Name:
            NameFull: Kazuharu Harada
      – PersonEntity:
          Name:
            NameFull: Masataka Taguri
      – PersonEntity:
          Name:
            NameFull: Takeshi Inoue
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 09
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-print
              Value: 27692558
          Numbering:
            – Type: volume
              Value: 2
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: PCN Reports
              Type: main
ResultId 1