Academic Journal
View in EDS
PDF Full Text

Tyrosine Sulfation as a Protein Post-Translational Modification

Bibliographic Details
Title: Tyrosine Sulfation as a Protein Post-Translational Modification
Authors: Yuh-Shyong Yang, Chen-Chu Wang, Bo-Han Chen, You-Hua Hou, Kuo-Sheng Hung, Yi-Chih Mao
Source: Molecules, Vol 20, Iss 2, Pp 2138-2164 (2015)
Publisher Information: MDPI AG, 2015.
Publication Year: 2015
Collection: LCC:Organic chemistry
Subject Terms: sulfate, organic sulfate, post-translational modification (PTM), protein tyrosine sulfation (PTS), tyrosylprotein sulfotransferase (TPST), 3'-phosphoadenosine 5'-phosphosulfate (PAPS), Organic chemistry, QD241-441
More Details: Integration of inorganic sulfate into biological molecules plays an important role in biological systems and is directly involved in the instigation of diseases. Protein tyrosine sulfation (PTS) is a common post-translational modification that was first reported in the literature fifty years ago. However, the significance of PTS under physiological conditions and its link to diseases have just begun to be appreciated in recent years. PTS is catalyzed by tyrosylprotein sulfotransferase (TPST) through transfer of an activated sulfate from 3'-phosphoadenosine-5'-phosphosulfate to tyrosine in a variety of proteins and peptides. Currently, only a small fraction of sulfated proteins is known and the understanding of the biological sulfation mechanisms is still in progress. In this review, we give an introductory and selective brief review of PTS and then summarize the basic biochemical information including the activity and the preparation of TPST, methods for the determination of PTS, and kinetics and reaction mechanism of TPST. This information is fundamental for the further exploration of the function of PTS that induces protein-protein interactions and the subsequent biochemical and physiological reactions.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1420-3049
Relation: http://www.mdpi.com/1420-3049/20/2/2138; https://doaj.org/toc/1420-3049
DOI: 10.3390/molecules20022138
Access URL: https://doaj.org/article/593f8554d843441ca8b89ba594aa6c59
Accession Number: edsdoj.593f8554d843441ca8b89ba594aa6c59
Database: Directory of Open Access Journals
FullText Links:
  – Type: pdflink
    Url: https://content.ebscohost.com/cds/retrieve?content=AQICAHjPtM4BHU3ZchRwgzYmadcigk49r9CVlbU7V5F6lgH7WwF7ROyNDhXnyDBwLXgSEDjRAAAA4jCB3wYJKoZIhvcNAQcGoIHRMIHOAgEAMIHIBgkqhkiG9w0BBwEwHgYJYIZIAWUDBAEuMBEEDGTwCDk1ynezIuudIAIBEICBmvAaNzPf9f28Fs0Y18uiFf5uBBxiVysZ87LhLArEuJ28AhEY2Qb7KsosETiavIZ29Vgd3xEnfDfCRasY-KNTeF-JBOX5amJLXbTOnAx9abbmaJt7_BWmEayZD5XlMUu2bvngomWmTPvyPT3RcroBD46Nv4TG9H4oqYsn5Te4nd-S4qATPU7A73bKerWvxKn3M4br6l9ZvQ4gzz0=
Text:
  Availability: 0
CustomLinks:
  – Url: https://resolver.ebsco.com/c/xy5jbn/result?sid=EBSCO:edsdoj&genre=article&issn=14203049&ISBN=&volume=20&issue=2&date=20150101&spage=2138&pages=2138-2164&title=Molecules&atitle=Tyrosine%20Sulfation%20as%20a%20Protein%20Post-Translational%20Modification&aulast=Yuh-Shyong%20Yang&id=DOI:10.3390/molecules20022138
    Name: Full Text Finder (for New FTF UI) (s8985755)
    Category: fullText
    Text: Find It @ SCU Libraries
    MouseOverText: Find It @ SCU Libraries
  – Url: https://doaj.org/article/593f8554d843441ca8b89ba594aa6c59
    Name: EDS - DOAJ (s8985755)
    Category: fullText
    Text: View record from DOAJ
    MouseOverText: View record from DOAJ
Header DbId: edsdoj
DbLabel: Directory of Open Access Journals
An: edsdoj.593f8554d843441ca8b89ba594aa6c59
RelevancyScore: 881
AccessLevel: 3
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 880.848266601563
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Tyrosine Sulfation as a Protein Post-Translational Modification
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Yuh-Shyong+Yang%22">Yuh-Shyong Yang</searchLink><br /><searchLink fieldCode="AR" term="%22Chen-Chu+Wang%22">Chen-Chu Wang</searchLink><br /><searchLink fieldCode="AR" term="%22Bo-Han+Chen%22">Bo-Han Chen</searchLink><br /><searchLink fieldCode="AR" term="%22You-Hua+Hou%22">You-Hua Hou</searchLink><br /><searchLink fieldCode="AR" term="%22Kuo-Sheng+Hung%22">Kuo-Sheng Hung</searchLink><br /><searchLink fieldCode="AR" term="%22Yi-Chih+Mao%22">Yi-Chih Mao</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: Molecules, Vol 20, Iss 2, Pp 2138-2164 (2015)
– Name: Publisher
  Label: Publisher Information
  Group: PubInfo
  Data: MDPI AG, 2015.
– Name: DatePubCY
  Label: Publication Year
  Group: Date
  Data: 2015
– Name: Subset
  Label: Collection
  Group: HoldingsInfo
  Data: LCC:Organic chemistry
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22sulfate%22">sulfate</searchLink><br /><searchLink fieldCode="DE" term="%22organic+sulfate%22">organic sulfate</searchLink><br /><searchLink fieldCode="DE" term="%22post-translational+modification+%28PTM%29%22">post-translational modification (PTM)</searchLink><br /><searchLink fieldCode="DE" term="%22protein+tyrosine+sulfation+%28PTS%29%22">protein tyrosine sulfation (PTS)</searchLink><br /><searchLink fieldCode="DE" term="%22tyrosylprotein+sulfotransferase+%28TPST%29%22">tyrosylprotein sulfotransferase (TPST)</searchLink><br /><searchLink fieldCode="DE" term="%223'-phosphoadenosine+5'-phosphosulfate+%28PAPS%29%22">3'-phosphoadenosine 5'-phosphosulfate (PAPS)</searchLink><br /><searchLink fieldCode="DE" term="%22Organic+chemistry%22">Organic chemistry</searchLink><br /><searchLink fieldCode="DE" term="%22QD241-441%22">QD241-441</searchLink>
– Name: Abstract
  Label: Description
  Group: Ab
  Data: Integration of inorganic sulfate into biological molecules plays an important role in biological systems and is directly involved in the instigation of diseases. Protein tyrosine sulfation (PTS) is a common post-translational modification that was first reported in the literature fifty years ago. However, the significance of PTS under physiological conditions and its link to diseases have just begun to be appreciated in recent years. PTS is catalyzed by tyrosylprotein sulfotransferase (TPST) through transfer of an activated sulfate from 3'-phosphoadenosine-5'-phosphosulfate to tyrosine in a variety of proteins and peptides. Currently, only a small fraction of sulfated proteins is known and the understanding of the biological sulfation mechanisms is still in progress. In this review, we give an introductory and selective brief review of PTS and then summarize the basic biochemical information including the activity and the preparation of TPST, methods for the determination of PTS, and kinetics and reaction mechanism of TPST. This information is fundamental for the further exploration of the function of PTS that induces protein-protein interactions and the subsequent biochemical and physiological reactions.
– Name: TypeDocument
  Label: Document Type
  Group: TypDoc
  Data: article
– Name: Format
  Label: File Description
  Group: SrcInfo
  Data: electronic resource
– Name: Language
  Label: Language
  Group: Lang
  Data: English
– Name: ISSN
  Label: ISSN
  Group: ISSN
  Data: 1420-3049
– Name: NoteTitleSource
  Label: Relation
  Group: SrcInfo
  Data: http://www.mdpi.com/1420-3049/20/2/2138; https://doaj.org/toc/1420-3049
– Name: DOI
  Label: DOI
  Group: ID
  Data: 10.3390/molecules20022138
– Name: URL
  Label: Access URL
  Group: URL
  Data: <link linkTarget="URL" linkTerm="https://doaj.org/article/593f8554d843441ca8b89ba594aa6c59" linkWindow="_blank">https://doaj.org/article/593f8554d843441ca8b89ba594aa6c59</link>
– Name: AN
  Label: Accession Number
  Group: ID
  Data: edsdoj.593f8554d843441ca8b89ba594aa6c59
PLink https://login.libproxy.scu.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edsdoj&AN=edsdoj.593f8554d843441ca8b89ba594aa6c59
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3390/molecules20022138
    Languages:
      – Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 27
        StartPage: 2138
    Subjects:
      – SubjectFull: sulfate
        Type: general
      – SubjectFull: organic sulfate
        Type: general
      – SubjectFull: post-translational modification (PTM)
        Type: general
      – SubjectFull: protein tyrosine sulfation (PTS)
        Type: general
      – SubjectFull: tyrosylprotein sulfotransferase (TPST)
        Type: general
      – SubjectFull: 3'-phosphoadenosine 5'-phosphosulfate (PAPS)
        Type: general
      – SubjectFull: Organic chemistry
        Type: general
      – SubjectFull: QD241-441
        Type: general
    Titles:
      – TitleFull: Tyrosine Sulfation as a Protein Post-Translational Modification
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Yuh-Shyong Yang
      – PersonEntity:
          Name:
            NameFull: Chen-Chu Wang
      – PersonEntity:
          Name:
            NameFull: Bo-Han Chen
      – PersonEntity:
          Name:
            NameFull: You-Hua Hou
      – PersonEntity:
          Name:
            NameFull: Kuo-Sheng Hung
      – PersonEntity:
          Name:
            NameFull: Yi-Chih Mao
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2015
          Identifiers:
            – Type: issn-print
              Value: 14203049
          Numbering:
            – Type: volume
              Value: 20
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Molecules
              Type: main
ResultId 1