Academic Journal
View in EDS

Cerebral Venous Thrombosis: A Challenging Diagnosis; A New Nonenhanced Computed Tomography Standardized Semi-Quantitative Method

Bibliographic Details
Title: Cerebral Venous Thrombosis: A Challenging Diagnosis; A New Nonenhanced Computed Tomography Standardized Semi-Quantitative Method
Authors: Andrea Romano, Maria Camilla Rossi-Espagnet, Luca Pasquini, Alberto Di Napoli, Francesco Dellepiane, Giulia Butera, Giulia Moltoni, Olga Gagliardo, Alessandro Bozzao
Source: Tomography, Vol 8, Iss 1, Pp 1-9 (2021)
Publisher Information: MDPI AG, 2021.
Publication Year: 2021
Collection: LCC:Computer applications to medicine. Medical informatics
Subject Terms: cerebral venous thrombosis, diagnosis, standardized method, CT, ROI based, Computer applications to medicine. Medical informatics, R858-859.7
More Details: Cerebral venous sinus thrombosis (CVST) on non-contrast CT (NCCT) is often challenging to detect. We retrospectively selected 41 children and 36 adults with confirmed CVST and two age-matched control groups with comparable initial symptoms. We evaluated NCCT placing four small circular ROIs in standardized regions of the cerebral dural venous system. The mean and maximum HU values were considered from each ROI, and the relative percentage variations were calculated (mean % variation and maximum % variation). We compared the highest measured value to the remaining three HU values through an ad-hoc formula based on the assumption that the thrombosed sinus has higher attenuation compared with the healthy sinuses. Percentage variations were employed to reflect how the attenuation of the thrombosed sinus deviates from the unaffected counterparts. The attenuation of the affected sinus was increased in patients with CVST, and consequently both the mean % and maximum % variations were increased. A mean % variation value of 12.97 and a maximum % variation value of 10.14 were found to be useful to distinguish patients with CVST from healthy subjects, with high sensitivity and specificity. Increased densitometric values were present in the site of venous thrombosis. A systematic, blind evaluation of the brain venous system can assist radiologists in identifying patients who need or do not need further imaging.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2379-139X
2379-1381
Relation: https://www.mdpi.com/2379-139X/8/1/1; https://doaj.org/toc/2379-1381; https://doaj.org/toc/2379-139X
DOI: 10.3390/tomography8010001
Access URL: https://doaj.org/article/c4afefca46c844e090af5ad092c3a15d
Accession Number: edsdoj.4afefca46c844e090af5ad092c3a15d
Database: Directory of Open Access Journals
FullText Text:
  Availability: 0
CustomLinks:
  – Url: https://resolver.ebsco.com/c/xy5jbn/result?sid=EBSCO:edsdoj&genre=article&issn=2379139X&ISBN=&volume=8&issue=1&date=20211201&spage=1&pages=1-9&title=Tomography&atitle=Cerebral%20Venous%20Thrombosis%3A%20A%20Challenging%20Diagnosis%3B%20A%20New%20Nonenhanced%20Computed%20Tomography%20Standardized%20Semi-Quantitative%20Method&aulast=Andrea%20Romano&id=DOI:10.3390/tomography8010001
    Name: Full Text Finder (for New FTF UI) (s8985755)
    Category: fullText
    Text: Find It @ SCU Libraries
    MouseOverText: Find It @ SCU Libraries
  – Url: https://doaj.org/article/c4afefca46c844e090af5ad092c3a15d
    Name: EDS - DOAJ (s8985755)
    Category: fullText
    Text: View record from DOAJ
    MouseOverText: View record from DOAJ
Header DbId: edsdoj
DbLabel: Directory of Open Access Journals
An: edsdoj.4afefca46c844e090af5ad092c3a15d
RelevancyScore: 957
AccessLevel: 3
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 956.691040039063
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Cerebral Venous Thrombosis: A Challenging Diagnosis; A New Nonenhanced Computed Tomography Standardized Semi-Quantitative Method
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Andrea+Romano%22">Andrea Romano</searchLink><br /><searchLink fieldCode="AR" term="%22Maria+Camilla+Rossi-Espagnet%22">Maria Camilla Rossi-Espagnet</searchLink><br /><searchLink fieldCode="AR" term="%22Luca+Pasquini%22">Luca Pasquini</searchLink><br /><searchLink fieldCode="AR" term="%22Alberto+Di+Napoli%22">Alberto Di Napoli</searchLink><br /><searchLink fieldCode="AR" term="%22Francesco+Dellepiane%22">Francesco Dellepiane</searchLink><br /><searchLink fieldCode="AR" term="%22Giulia+Butera%22">Giulia Butera</searchLink><br /><searchLink fieldCode="AR" term="%22Giulia+Moltoni%22">Giulia Moltoni</searchLink><br /><searchLink fieldCode="AR" term="%22Olga+Gagliardo%22">Olga Gagliardo</searchLink><br /><searchLink fieldCode="AR" term="%22Alessandro+Bozzao%22">Alessandro Bozzao</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: Tomography, Vol 8, Iss 1, Pp 1-9 (2021)
– Name: Publisher
  Label: Publisher Information
  Group: PubInfo
  Data: MDPI AG, 2021.
– Name: DatePubCY
  Label: Publication Year
  Group: Date
  Data: 2021
– Name: Subset
  Label: Collection
  Group: HoldingsInfo
  Data: LCC:Computer applications to medicine. Medical informatics
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22cerebral+venous+thrombosis%22">cerebral venous thrombosis</searchLink><br /><searchLink fieldCode="DE" term="%22diagnosis%22">diagnosis</searchLink><br /><searchLink fieldCode="DE" term="%22standardized+method%22">standardized method</searchLink><br /><searchLink fieldCode="DE" term="%22CT%22">CT</searchLink><br /><searchLink fieldCode="DE" term="%22ROI+based%22">ROI based</searchLink><br /><searchLink fieldCode="DE" term="%22Computer+applications+to+medicine%2E+Medical+informatics%22">Computer applications to medicine. Medical informatics</searchLink><br /><searchLink fieldCode="DE" term="%22R858-859%2E7%22">R858-859.7</searchLink>
– Name: Abstract
  Label: Description
  Group: Ab
  Data: Cerebral venous sinus thrombosis (CVST) on non-contrast CT (NCCT) is often challenging to detect. We retrospectively selected 41 children and 36 adults with confirmed CVST and two age-matched control groups with comparable initial symptoms. We evaluated NCCT placing four small circular ROIs in standardized regions of the cerebral dural venous system. The mean and maximum HU values were considered from each ROI, and the relative percentage variations were calculated (mean % variation and maximum % variation). We compared the highest measured value to the remaining three HU values through an ad-hoc formula based on the assumption that the thrombosed sinus has higher attenuation compared with the healthy sinuses. Percentage variations were employed to reflect how the attenuation of the thrombosed sinus deviates from the unaffected counterparts. The attenuation of the affected sinus was increased in patients with CVST, and consequently both the mean % and maximum % variations were increased. A mean % variation value of 12.97 and a maximum % variation value of 10.14 were found to be useful to distinguish patients with CVST from healthy subjects, with high sensitivity and specificity. Increased densitometric values were present in the site of venous thrombosis. A systematic, blind evaluation of the brain venous system can assist radiologists in identifying patients who need or do not need further imaging.
– Name: TypeDocument
  Label: Document Type
  Group: TypDoc
  Data: article
– Name: Format
  Label: File Description
  Group: SrcInfo
  Data: electronic resource
– Name: Language
  Label: Language
  Group: Lang
  Data: English
– Name: ISSN
  Label: ISSN
  Group: ISSN
  Data: 2379-139X<br />2379-1381
– Name: NoteTitleSource
  Label: Relation
  Group: SrcInfo
  Data: https://www.mdpi.com/2379-139X/8/1/1; https://doaj.org/toc/2379-1381; https://doaj.org/toc/2379-139X
– Name: DOI
  Label: DOI
  Group: ID
  Data: 10.3390/tomography8010001
– Name: URL
  Label: Access URL
  Group: URL
  Data: <link linkTarget="URL" linkTerm="https://doaj.org/article/c4afefca46c844e090af5ad092c3a15d" linkWindow="_blank">https://doaj.org/article/c4afefca46c844e090af5ad092c3a15d</link>
– Name: AN
  Label: Accession Number
  Group: ID
  Data: edsdoj.4afefca46c844e090af5ad092c3a15d
PLink https://login.libproxy.scu.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edsdoj&AN=edsdoj.4afefca46c844e090af5ad092c3a15d
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3390/tomography8010001
    Languages:
      – Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 9
        StartPage: 1
    Subjects:
      – SubjectFull: cerebral venous thrombosis
        Type: general
      – SubjectFull: diagnosis
        Type: general
      – SubjectFull: standardized method
        Type: general
      – SubjectFull: CT
        Type: general
      – SubjectFull: ROI based
        Type: general
      – SubjectFull: Computer applications to medicine. Medical informatics
        Type: general
      – SubjectFull: R858-859.7
        Type: general
    Titles:
      – TitleFull: Cerebral Venous Thrombosis: A Challenging Diagnosis; A New Nonenhanced Computed Tomography Standardized Semi-Quantitative Method
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Andrea Romano
      – PersonEntity:
          Name:
            NameFull: Maria Camilla Rossi-Espagnet
      – PersonEntity:
          Name:
            NameFull: Luca Pasquini
      – PersonEntity:
          Name:
            NameFull: Alberto Di Napoli
      – PersonEntity:
          Name:
            NameFull: Francesco Dellepiane
      – PersonEntity:
          Name:
            NameFull: Giulia Butera
      – PersonEntity:
          Name:
            NameFull: Giulia Moltoni
      – PersonEntity:
          Name:
            NameFull: Olga Gagliardo
      – PersonEntity:
          Name:
            NameFull: Alessandro Bozzao
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 12
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-print
              Value: 2379139X
            – Type: issn-print
              Value: 23791381
          Numbering:
            – Type: volume
              Value: 8
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Tomography
              Type: main
ResultId 1