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Whole-Blood MicroRNA Sequence Profiling and Identification of Specific miR-21 for Adolescents With Postural Tachycardia Syndrome

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Title: Whole-Blood MicroRNA Sequence Profiling and Identification of Specific miR-21 for Adolescents With Postural Tachycardia Syndrome
Authors: Jing Lin, Jie Shen, Juan Liu, Wenjie Cheng, Lintian Li, Fuyong Jiao
Source: Frontiers in Neuroscience, Vol 16 (2022)
Publisher Information: Frontiers Media S.A., 2022.
Publication Year: 2022
Collection: LCC:Neurosciences. Biological psychiatry. Neuropsychiatry
Subject Terms: postural tachycardia syndrome, whole blood, high-throughput sequencing, miR-21, adolescents, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
More Details: ObjectiveThe aim of the study was to establish whether whole-blood microRNA (miRNA) profiles differ between postural tachycardia syndrome (POTS) sufferers and control subjects and to identify the miRNA that regulates plasma H2S.Study DesignHigh-throughput sequencing was used to obtain whole-blood miRNA expression profiles for 20 POTS sufferers and 20 normal children.The thresholds for defining differentially expressed miRNAs (DEmiRNAs) were an adjusted DESeq P of
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1662-453X
Relation: https://www.frontiersin.org/articles/10.3389/fnins.2022.920477/full; https://doaj.org/toc/1662-453X
DOI: 10.3389/fnins.2022.920477
Access URL: https://doaj.org/article/0b5ece69ca884ae994052c9dd3377ec4
Accession Number: edsdoj.0b5ece69ca884ae994052c9dd3377ec4
Database: Directory of Open Access Journals
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  Data: Whole-Blood MicroRNA Sequence Profiling and Identification of Specific miR-21 for Adolescents With Postural Tachycardia Syndrome
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  Data: <searchLink fieldCode="AR" term="%22Jing+Lin%22">Jing Lin</searchLink><br /><searchLink fieldCode="AR" term="%22Jie+Shen%22">Jie Shen</searchLink><br /><searchLink fieldCode="AR" term="%22Juan+Liu%22">Juan Liu</searchLink><br /><searchLink fieldCode="AR" term="%22Wenjie+Cheng%22">Wenjie Cheng</searchLink><br /><searchLink fieldCode="AR" term="%22Lintian+Li%22">Lintian Li</searchLink><br /><searchLink fieldCode="AR" term="%22Fuyong+Jiao%22">Fuyong Jiao</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22postural+tachycardia+syndrome%22">postural tachycardia syndrome</searchLink><br /><searchLink fieldCode="DE" term="%22whole+blood%22">whole blood</searchLink><br /><searchLink fieldCode="DE" term="%22high-throughput+sequencing%22">high-throughput sequencing</searchLink><br /><searchLink fieldCode="DE" term="%22miR-21%22">miR-21</searchLink><br /><searchLink fieldCode="DE" term="%22adolescents%22">adolescents</searchLink><br /><searchLink fieldCode="DE" term="%22Neurosciences%2E+Biological+psychiatry%2E+Neuropsychiatry%22">Neurosciences. Biological psychiatry. Neuropsychiatry</searchLink><br /><searchLink fieldCode="DE" term="%22RC321-571%22">RC321-571</searchLink>
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  Data: ObjectiveThe aim of the study was to establish whether whole-blood microRNA (miRNA) profiles differ between postural tachycardia syndrome (POTS) sufferers and control subjects and to identify the miRNA that regulates plasma H2S.Study DesignHigh-throughput sequencing was used to obtain whole-blood miRNA expression profiles for 20 POTS sufferers and 20 normal children.The thresholds for defining differentially expressed miRNAs (DEmiRNAs) were an adjusted DESeq P of
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      – SubjectFull: postural tachycardia syndrome
        Type: general
      – SubjectFull: whole blood
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      – SubjectFull: high-throughput sequencing
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      – SubjectFull: miR-21
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      – TitleFull: Whole-Blood MicroRNA Sequence Profiling and Identification of Specific miR-21 for Adolescents With Postural Tachycardia Syndrome
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