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Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research

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Title: Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research
Contributors: Tanaka, Masaru
Publisher Information: MDPI - Multidisciplinary Digital Publishing Institute, 2024.
Publication Year: 2024
Subject Terms: epilepsy surgery, medically refractory focal epilepsy, presurgical evaluation, MRI-negative patients, discordant electroclinical and MRI data, metabolic PET, hybrid [18F]-FDG PET/MRI, preoperative workflow, concordance analysis, epilepsy team, aspirin resistance, genetic markers, genetics, machine learning, CatBoost, ischemic stroke, SNP, pharmacogenetics, platelet aggregation, biochip, primary headache, migraine, trigeminal system, CGRP, nNOS, neurogenic inflammation, animal model, inflammatory soup, dura mater, estrogen, behavior, respiratory sinus arrhythmia, directed information flow, neural pacemaker-like activity, fMRI-related anxiety, anxiety management, causal coupling, breathing rhythm, neural BOLD oscillations, cardio-respiratory coupling, breathing-entrained oscillations, transient receptor potential channels, antibody, reperfusion injury, middle cerebral artery occlusion, model, vascular, protection, hypoxia, stroke, therapy, age groups, attention, brain, cognition, default mode network, executive function, exercise, magnetic resonance imaging, memory, mental health, depression, cardiovascular disease, obesity, diabetes, civilization diseases, mental disorders, risk factors, inflammation, interleukins, comorbidity, cord blood stem cell transplantation, genetic vectors, vascular endothelial growth factor A, transcriptome, secretome, biosafety, genetic therapy, oxidative stresses, neuroinflammation, traumatic brain injuries, intensive care, sedatives, antioxidant effects, biologic monitoring, barbiturates, electron spin resonance, translational research, Parkinson’s disease, transcranial direct current stimulation, motor skill, cerebellum, cerebellar stimulation, motor learning, manual dexterity, dopamine, basal ganglia, transfer of motor learning, translational neuroscience, neuroplasticity, aphasia, rehabilitation, language impairment, cognitive recovery, animals, language, physical health, psychosis, risk, CHR-P, Medicine: general issues
More Details: The Special Issue, "Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research," delves into the complexities of neurological and psychiatric disorders, which affect millions worldwide. Despite advances, the etiology and pathogenesis of these disorders remain largely unknown, and current treatments often fall short or have adverse effects. This issue emphasizes the urgent need for new strategies to prevent, diagnose, and treat these disorders. It underscores the importance of establishing reliable models that can recapitulate the complex interactions between genetic, epigenetic, environmental, and pharmacological factors contributing to these disorders. The issue presents 12 articles covering a wide range of topics and methods in neuroscience and neurology, highlighting the potential of novel interventions that can modulate the molecular and functional alterations underlying these disorders. It aims to stimulate further research and collaboration among researchers and clinicians, inspire new ideas and innovations, and ultimately benefit patients and society. Readers can explore the diverse and exciting topics presented in this collection. We extend our gratitude to all authors and reviewers for their contributions to this Special Issue.
Document Type: eBook
File Description: application/octet-stream
Language: English
ISBN: 978-3-7258-0821-2
978-3-7258-0822-9
DOI: 10.3390/books978-3-7258-0822-9
Access URL: https://directory.doabooks.org/handle/20.500.12854/137876
https://mdpi.com/books/pdfview/book/9117
Rights: Attribution-NonCommercial-NoDerivatives 4.0 International
open access
URL: http://purl.org/coar/access_right/c_abf2
URL: https://creativecommons.org/licenses/by-nc-nd/4.0/
Notes: ONIX_20240514_9783725808212_472
Accession Number: edsdob.20.500.12854.137876
Database: Directory of Open Access Books
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  Data: Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research
– Name: Author
  Label: Contributors
  Group: Au
  Data: Tanaka, Masaru
– Name: Publisher
  Label: Publisher Information
  Group: PubInfo
  Data: MDPI - Multidisciplinary Digital Publishing Institute, 2024.
– Name: DatePubCY
  Label: Publication Year
  Group: Date
  Data: 2024
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22epilepsy+surgery%22">epilepsy surgery</searchLink><br /><searchLink fieldCode="DE" term="%22medically+refractory+focal+epilepsy%22">medically refractory focal epilepsy</searchLink><br /><searchLink fieldCode="DE" term="%22presurgical+evaluation%22">presurgical evaluation</searchLink><br /><searchLink fieldCode="DE" term="%22MRI-negative+patients%22">MRI-negative patients</searchLink><br /><searchLink fieldCode="DE" term="%22discordant+electroclinical+and+MRI+data%22">discordant electroclinical and MRI data</searchLink><br /><searchLink fieldCode="DE" term="%22metabolic+PET%22">metabolic PET</searchLink><br /><searchLink fieldCode="DE" term="%22hybrid+[18F]-FDG+PET%2FMRI%22">hybrid [18F]-FDG PET/MRI</searchLink><br /><searchLink fieldCode="DE" term="%22preoperative+workflow%22">preoperative workflow</searchLink><br /><searchLink fieldCode="DE" term="%22concordance+analysis%22">concordance analysis</searchLink><br /><searchLink fieldCode="DE" 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term="%22transcriptome%22">transcriptome</searchLink><br /><searchLink fieldCode="DE" term="%22secretome%22">secretome</searchLink><br /><searchLink fieldCode="DE" term="%22biosafety%22">biosafety</searchLink><br /><searchLink fieldCode="DE" term="%22genetic+therapy%22">genetic therapy</searchLink><br /><searchLink fieldCode="DE" term="%22oxidative+stresses%22">oxidative stresses</searchLink><br /><searchLink fieldCode="DE" term="%22neuroinflammation%22">neuroinflammation</searchLink><br /><searchLink fieldCode="DE" term="%22traumatic+brain+injuries%22">traumatic brain injuries</searchLink><br /><searchLink fieldCode="DE" term="%22intensive+care%22">intensive care</searchLink><br /><searchLink fieldCode="DE" term="%22sedatives%22">sedatives</searchLink><br /><searchLink fieldCode="DE" term="%22antioxidant+effects%22">antioxidant effects</searchLink><br /><searchLink fieldCode="DE" term="%22biologic+monitoring%22">biologic monitoring</searchLink><br /><searchLink fieldCode="DE" 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term="%22physical+health%22">physical health</searchLink><br /><searchLink fieldCode="DE" term="%22psychosis%22">psychosis</searchLink><br /><searchLink fieldCode="DE" term="%22risk%22">risk</searchLink><br /><searchLink fieldCode="DE" term="%22CHR-P%22">CHR-P</searchLink><br /><searchLink fieldCode="DE" term="%22Medicine%3A+general+issues%22">Medicine: general issues</searchLink>
– Name: Abstract
  Label: Description
  Group: Ab
  Data: The Special Issue, "Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research," delves into the complexities of neurological and psychiatric disorders, which affect millions worldwide. Despite advances, the etiology and pathogenesis of these disorders remain largely unknown, and current treatments often fall short or have adverse effects. This issue emphasizes the urgent need for new strategies to prevent, diagnose, and treat these disorders. It underscores the importance of establishing reliable models that can recapitulate the complex interactions between genetic, epigenetic, environmental, and pharmacological factors contributing to these disorders. The issue presents 12 articles covering a wide range of topics and methods in neuroscience and neurology, highlighting the potential of novel interventions that can modulate the molecular and functional alterations underlying these disorders. It aims to stimulate further research and collaboration among researchers and clinicians, inspire new ideas and innovations, and ultimately benefit patients and society. Readers can explore the diverse and exciting topics presented in this collection. We extend our gratitude to all authors and reviewers for their contributions to this Special Issue.
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  Label: Document Type
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  Data: eBook
– Name: Format
  Label: File Description
  Group: SrcInfo
  Data: application/octet-stream
– Name: Language
  Label: Language
  Group: Lang
  Data: English
– Name: ISBN
  Label: ISBN
  Group: ISBN
  Data: 978-3-7258-0821-2<br />978-3-7258-0822-9
– Name: DOI
  Label: DOI
  Group: ID
  Data: 10.3390/books978-3-7258-0822-9
– Name: URL
  Label: Access URL
  Group: URL
  Data: <link linkTarget="URL" linkTerm="https://directory.doabooks.org/handle/20.500.12854/137876" linkWindow="_blank">https://directory.doabooks.org/handle/20.500.12854/137876</link><br /><link linkTarget="URL" linkTerm="https://mdpi.com/books/pdfview/book/9117" linkWindow="_blank">https://mdpi.com/books/pdfview/book/9117</link>
– Name: Copyright
  Label: Rights
  Group: Cpyrght
  Data: Attribution-NonCommercial-NoDerivatives 4.0 International<br />open access<br />URL: http://purl.org/coar/access_right/c_abf2<br />URL: https://creativecommons.org/licenses/by-nc-nd/4.0/
– Name: Note
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  Group:
  Data: ONIX_20240514_9783725808212_472
– Name: AN
  Label: Accession Number
  Group: ID
  Data: edsdob.20.500.12854.137876
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    Identifiers:
      – Type: doi
        Value: 10.3390/books978-3-7258-0822-9
    Languages:
      – Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 248
    Subjects:
      – SubjectFull: epilepsy surgery
        Type: general
      – SubjectFull: medically refractory focal epilepsy
        Type: general
      – SubjectFull: presurgical evaluation
        Type: general
      – SubjectFull: MRI-negative patients
        Type: general
      – SubjectFull: discordant electroclinical and MRI data
        Type: general
      – SubjectFull: metabolic PET
        Type: general
      – SubjectFull: hybrid [18F]-FDG PET/MRI
        Type: general
      – SubjectFull: preoperative workflow
        Type: general
      – SubjectFull: concordance analysis
        Type: general
      – SubjectFull: epilepsy team
        Type: general
      – SubjectFull: aspirin resistance
        Type: general
      – SubjectFull: genetic markers
        Type: general
      – SubjectFull: genetics
        Type: general
      – SubjectFull: machine learning
        Type: general
      – SubjectFull: CatBoost
        Type: general
      – SubjectFull: ischemic stroke
        Type: general
      – SubjectFull: SNP
        Type: general
      – SubjectFull: pharmacogenetics
        Type: general
      – SubjectFull: platelet aggregation
        Type: general
      – SubjectFull: biochip
        Type: general
      – SubjectFull: primary headache
        Type: general
      – SubjectFull: migraine
        Type: general
      – SubjectFull: trigeminal system
        Type: general
      – SubjectFull: CGRP
        Type: general
      – SubjectFull: nNOS
        Type: general
      – SubjectFull: neurogenic inflammation
        Type: general
      – SubjectFull: animal model
        Type: general
      – SubjectFull: inflammatory soup
        Type: general
      – SubjectFull: dura mater
        Type: general
      – SubjectFull: estrogen
        Type: general
      – SubjectFull: behavior
        Type: general
      – SubjectFull: respiratory sinus arrhythmia
        Type: general
      – SubjectFull: directed information flow
        Type: general
      – SubjectFull: neural pacemaker-like activity
        Type: general
      – SubjectFull: fMRI-related anxiety
        Type: general
      – SubjectFull: anxiety management
        Type: general
      – SubjectFull: causal coupling
        Type: general
      – SubjectFull: breathing rhythm
        Type: general
      – SubjectFull: neural BOLD oscillations
        Type: general
      – SubjectFull: cardio-respiratory coupling
        Type: general
      – SubjectFull: breathing-entrained oscillations
        Type: general
      – SubjectFull: transient receptor potential channels
        Type: general
      – SubjectFull: antibody
        Type: general
      – SubjectFull: reperfusion injury
        Type: general
      – SubjectFull: middle cerebral artery occlusion
        Type: general
      – SubjectFull: model
        Type: general
      – SubjectFull: vascular
        Type: general
      – SubjectFull: protection
        Type: general
      – SubjectFull: hypoxia
        Type: general
      – SubjectFull: stroke
        Type: general
      – SubjectFull: therapy
        Type: general
      – SubjectFull: age groups
        Type: general
      – SubjectFull: attention
        Type: general
      – SubjectFull: brain
        Type: general
      – SubjectFull: cognition
        Type: general
      – SubjectFull: default mode network
        Type: general
      – SubjectFull: executive function
        Type: general
      – SubjectFull: exercise
        Type: general
      – SubjectFull: magnetic resonance imaging
        Type: general
      – SubjectFull: memory
        Type: general
      – SubjectFull: mental health
        Type: general
      – SubjectFull: depression
        Type: general
      – SubjectFull: cardiovascular disease
        Type: general
      – SubjectFull: obesity
        Type: general
      – SubjectFull: diabetes
        Type: general
      – SubjectFull: civilization diseases
        Type: general
      – SubjectFull: mental disorders
        Type: general
      – SubjectFull: risk factors
        Type: general
      – SubjectFull: inflammation
        Type: general
      – SubjectFull: interleukins
        Type: general
      – SubjectFull: comorbidity
        Type: general
      – SubjectFull: cord blood stem cell transplantation
        Type: general
      – SubjectFull: genetic vectors
        Type: general
      – SubjectFull: vascular endothelial growth factor A
        Type: general
      – SubjectFull: transcriptome
        Type: general
      – SubjectFull: secretome
        Type: general
      – SubjectFull: biosafety
        Type: general
      – SubjectFull: genetic therapy
        Type: general
      – SubjectFull: oxidative stresses
        Type: general
      – SubjectFull: neuroinflammation
        Type: general
      – SubjectFull: traumatic brain injuries
        Type: general
      – SubjectFull: intensive care
        Type: general
      – SubjectFull: sedatives
        Type: general
      – SubjectFull: antioxidant effects
        Type: general
      – SubjectFull: biologic monitoring
        Type: general
      – SubjectFull: barbiturates
        Type: general
      – SubjectFull: electron spin resonance
        Type: general
      – SubjectFull: translational research
        Type: general
      – SubjectFull: Parkinson’s disease
        Type: general
      – SubjectFull: transcranial direct current stimulation
        Type: general
      – SubjectFull: motor skill
        Type: general
      – SubjectFull: cerebellum
        Type: general
      – SubjectFull: cerebellar stimulation
        Type: general
      – SubjectFull: motor learning
        Type: general
      – SubjectFull: manual dexterity
        Type: general
      – SubjectFull: dopamine
        Type: general
      – SubjectFull: basal ganglia
        Type: general
      – SubjectFull: transfer of motor learning
        Type: general
      – SubjectFull: translational neuroscience
        Type: general
      – SubjectFull: neuroplasticity
        Type: general
      – SubjectFull: aphasia
        Type: general
      – SubjectFull: rehabilitation
        Type: general
      – SubjectFull: language impairment
        Type: general
      – SubjectFull: cognitive recovery
        Type: general
      – SubjectFull: animals
        Type: general
      – SubjectFull: language
        Type: general
      – SubjectFull: physical health
        Type: general
      – SubjectFull: psychosis
        Type: general
      – SubjectFull: risk
        Type: general
      – SubjectFull: CHR-P
        Type: general
      – SubjectFull: Medicine: general issues
        Type: general
    Titles:
      – TitleFull: Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Tanaka, Masaru
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2024
          Identifiers:
            – Type: isbn-print
              Value: 9783725808212
            – Type: isbn-print
              Value: 9783725808229
ResultId 1