The p.P1127S pathogenic variant lowers von Willebrand factor levels through higher affinity for the macrophagic scavenger receptor LRP1: Clinical phenotype and pathogenic mechanisms

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Title: The p.P1127S pathogenic variant lowers von Willebrand factor levels through higher affinity for the macrophagic scavenger receptor LRP1: Clinical phenotype and pathogenic mechanisms
Authors: Sacco, Monica, Lancellotti, Stefano, Branchini, Alessio, Tardugno, Maira, Testa, Maria Francesca, Lunghi, Barbara, Bernardi, Francesco, Pinotti, Mirko, Giusti, Betti, Castaman, Giancarlo, De Cristofaro, Raimondo
Source: Journal of thrombosis and haemostasis. 20(8):1818-1829
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  Data: The p.P1127S pathogenic variant lowers von Willebrand factor levels through higher affinity for the macrophagic scavenger receptor LRP1: Clinical phenotype and pathogenic mechanisms
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  Data: <searchLink fieldCode="AR" term="%22Sacco%2C+Monica%22">Sacco, Monica</searchLink><br /><searchLink fieldCode="AR" term="%22Lancellotti%2C+Stefano%22">Lancellotti, Stefano</searchLink><br /><searchLink fieldCode="AR" term="%22Branchini%2C+Alessio%22">Branchini, Alessio</searchLink><br /><searchLink fieldCode="AR" term="%22Tardugno%2C+Maira%22">Tardugno, Maira</searchLink><br /><searchLink fieldCode="AR" term="%22Testa%2C+Maria+Francesca%22">Testa, Maria Francesca</searchLink><br /><searchLink fieldCode="AR" term="%22Lunghi%2C+Barbara%22">Lunghi, Barbara</searchLink><br /><searchLink fieldCode="AR" term="%22Bernardi%2C+Francesco%22">Bernardi, Francesco</searchLink><br /><searchLink fieldCode="AR" term="%22Pinotti%2C+Mirko%22">Pinotti, Mirko</searchLink><br /><searchLink fieldCode="AR" term="%22Giusti%2C+Betti%22">Giusti, Betti</searchLink><br /><searchLink fieldCode="AR" term="%22Castaman%2C+Giancarlo%22">Castaman, Giancarlo</searchLink><br /><searchLink fieldCode="AR" term="%22De+Cristofaro%2C+Raimondo%22">De Cristofaro, Raimondo</searchLink>
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  Data: <i>Journal of thrombosis and haemostasis</i>. 20(8):1818-1829
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      – Text: English
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        PageCount: 12
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      – TitleFull: The p.P1127S pathogenic variant lowers von Willebrand factor levels through higher affinity for the macrophagic scavenger receptor LRP1: Clinical phenotype and pathogenic mechanisms
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            – D: 01
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              Type: published
              Y: 2022
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