Bibliographic Details
| Title: |
Aerobic Benzylic C(sp3)–H Bond Oxygenations Catalyzed by NBS under Visible Light Irradiation |
| Authors: |
Ye, Taiqiang, Li, Yuzheng, Ma, Yanni, Tan, Shenpeng, Li, Feng |
| Source: |
The Journal of Organic Chemistry; January 2024, Vol. 89 Issue: 1 p534-540, 7p |
| Abstract: |
An efficient photocatalytic oxidation of benzylic C(sp3)–H bonds to ketones, esters, and amides has been developed using NBS as a metal-free photocatalyst and O2as an oxidant. A variety of synthetically and biologically valuable compounds are assembled in moderate to excellent yields. The synthetic utility of this approach has been demonstrated by gram-scale experiments. A possible free radical mechanism was proposed to rationalize the reaction procedure. |
| Database: |
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