Analysis of Checkpoint Responses to Histone Deacetylase Inhibitors.

Bibliographic Details
Title: Analysis of Checkpoint Responses to Histone Deacetylase Inhibitors.
Authors: Walker, John M., Schönthal, Axel H., Beamish, Heather, Warrener, Robyn, Gabrielli, Brian G.
Source: Checkpoint Controls & Cancer (978-1-58829-500-2); 2004, p245-259, 15p
Abstract: Cell cycle checkpoints respond to a wide range of stresses to prevent compromise to the integrity of the cell. The best studied checkpoints are those induced by genotoxic agents that cause DNA damage. Histone deacetylase inhibitors not only increase the acetylation state of chromatin histones, but they also perturb the cell cycle, causing both G1 and G2 phase arrests, the latter by initiating a checkpoint response. In this chapter we will describe the analysis of the histone deacetylase inhibitor-sensitive G2 checkpoint using synchronized cell populations. [ABSTRACT FROM AUTHOR]
Copyright of Checkpoint Controls & Cancer (978-1-58829-500-2) is the property of Springer eBooks and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Supplemental Index
FullText Text:
  Availability: 0
CustomLinks:
  – Url: https://resolver.ebsco.com/c/xy5jbn/result?sid=EBSCO:edo&genre=book&issn=&ISBN=9781588295002&volume=&issue=&date=&spage=245&pages=245-259&title=Checkpoint Controls & Cancer (978-1-58829-500-2)&atitle=Analysis%20of%20Checkpoint%20Responses%20to%20Histone%20Deacetylase%20Inhibitors.&aulast=Walker%2C%20John%20M.&id=DOI:10.1385/1-59259-811-0:245
    Name: Full Text Finder (for New FTF UI) (s8985755)
    Category: fullText
    Text: Find It @ SCU Libraries
    MouseOverText: Find It @ SCU Libraries
Header DbId: edo
DbLabel: Supplemental Index
An: 33108248
RelevancyScore: 847
AccessLevel: 6
PubType: Book
PubTypeId: book
PreciseRelevancyScore: 847.044677734375
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Analysis of Checkpoint Responses to Histone Deacetylase Inhibitors.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Walker%2C+John+M%2E%22">Walker, John M.</searchLink><br /><searchLink fieldCode="AR" term="%22Schönthal%2C+Axel+H%2E%22">Schönthal, Axel H.</searchLink><br /><searchLink fieldCode="AR" term="%22Beamish%2C+Heather%22">Beamish, Heather</searchLink><br /><searchLink fieldCode="AR" term="%22Warrener%2C+Robyn%22">Warrener, Robyn</searchLink><br /><searchLink fieldCode="AR" term="%22Gabrielli%2C+Brian+G%2E%22">Gabrielli, Brian G.</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: Checkpoint Controls & Cancer (978-1-58829-500-2); 2004, p245-259, 15p
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Cell cycle checkpoints respond to a wide range of stresses to prevent compromise to the integrity of the cell. The best studied checkpoints are those induced by genotoxic agents that cause DNA damage. Histone deacetylase inhibitors not only increase the acetylation state of chromatin histones, but they also perturb the cell cycle, causing both G1 and G2 phase arrests, the latter by initiating a checkpoint response. In this chapter we will describe the analysis of the histone deacetylase inhibitor-sensitive G2 checkpoint using synchronized cell populations. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label:
  Group: Ab
  Data: <i>Copyright of Checkpoint Controls & Cancer (978-1-58829-500-2) is the property of Springer eBooks and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://login.libproxy.scu.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edo&AN=33108248
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1385/1-59259-811-0:245
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 15
        StartPage: 245
    Titles:
      – TitleFull: Analysis of Checkpoint Responses to Histone Deacetylase Inhibitors.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Walker, John M.
      – PersonEntity:
          Name:
            NameFull: Schönthal, Axel H.
      – PersonEntity:
          Name:
            NameFull: Beamish, Heather
      – PersonEntity:
          Name:
            NameFull: Warrener, Robyn
      – PersonEntity:
          Name:
            NameFull: Gabrielli, Brian G.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Text: 2004
              Type: published
              Y: 2004
          Identifiers:
            – Type: isbn-print
              Value: 9781588295002
          Titles:
            – TitleFull: Checkpoint Controls & Cancer (978-1-58829-500-2)
              Type: main
ResultId 1