Distribution of intrapleural and intravenous Corynebacterium parvum in humans; Tc, and I-labeled bacteria.
| Title: | Distribution of intrapleural and intravenous Corynebacterium parvum in humans; Tc, and I-labeled bacteria. |
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| Authors: | Kaufmann, Max, Marqverson, Jorgen, Stanley, Kenneth, Mouritzen, Christian, Hvid-Hansen, Hans |
| Source: | Cancer Immunology, Immunotherapy; May1986, Vol. 22 Issue 1, p56-61, 6p |
| Abstract: | The distribution of Corynebacterium parvum labeled with iodine or technetium was studied in 17 patients with bronchogenic carcinoma. The labeled bacteria were given intravenously or intrapleurally and monitored by whole-body gamma tracking and samples of blood and urine. Even though the rate of physical decay is quite different for iodine and technetium, the tracking time of labeled bacteria was limited to 24 h after injection for both radioactive isotopes. Technetium labeling was preferred because of greater imaging resolution and less radiation dose to the patient. Following intravenous administration, labeled C. parvum was found predominantly in the liver and spleen, and in a lesser amount in the lung. Radioactivity was confined to the pleural cavity after intrapleural injection. These results suggest the combined intravenous and intrapleural route of adjuvant immunosupportive agents such as C. parvum for operable lung cancer patients. [ABSTRACT FROM AUTHOR] |
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| Database: | Complementary Index |
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| Items | – Name: Title Label: Title Group: Ti Data: Distribution of intrapleural and intravenous Corynebacterium parvum in humans; Tc, and I-labeled bacteria. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Kaufmann%2C+Max%22">Kaufmann, Max</searchLink><br /><searchLink fieldCode="AR" term="%22Marqverson%2C+Jorgen%22">Marqverson, Jorgen</searchLink><br /><searchLink fieldCode="AR" term="%22Stanley%2C+Kenneth%22">Stanley, Kenneth</searchLink><br /><searchLink fieldCode="AR" term="%22Mouritzen%2C+Christian%22">Mouritzen, Christian</searchLink><br /><searchLink fieldCode="AR" term="%22Hvid-Hansen%2C+Hans%22">Hvid-Hansen, Hans</searchLink> – Name: TitleSource Label: Source Group: Src Data: Cancer Immunology, Immunotherapy; May1986, Vol. 22 Issue 1, p56-61, 6p – Name: Abstract Label: Abstract Group: Ab Data: The distribution of Corynebacterium parvum labeled with iodine or technetium was studied in 17 patients with bronchogenic carcinoma. The labeled bacteria were given intravenously or intrapleurally and monitored by whole-body gamma tracking and samples of blood and urine. Even though the rate of physical decay is quite different for iodine and technetium, the tracking time of labeled bacteria was limited to 24 h after injection for both radioactive isotopes. Technetium labeling was preferred because of greater imaging resolution and less radiation dose to the patient. Following intravenous administration, labeled C. parvum was found predominantly in the liver and spleen, and in a lesser amount in the lung. Radioactivity was confined to the pleural cavity after intrapleural injection. These results suggest the combined intravenous and intrapleural route of adjuvant immunosupportive agents such as C. parvum for operable lung cancer patients. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Group: Ab Data: <i>Copyright of Cancer Immunology, Immunotherapy is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/BF00205717 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 6 StartPage: 56 Titles: – TitleFull: Distribution of intrapleural and intravenous Corynebacterium parvum in humans; Tc, and I-labeled bacteria. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kaufmann, Max – PersonEntity: Name: NameFull: Marqverson, Jorgen – PersonEntity: Name: NameFull: Stanley, Kenneth – PersonEntity: Name: NameFull: Mouritzen, Christian – PersonEntity: Name: NameFull: Hvid-Hansen, Hans IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: May1986 Type: published Y: 1986 Identifiers: – Type: issn-print Value: 03407004 Numbering: – Type: volume Value: 22 – Type: issue Value: 1 Titles: – TitleFull: Cancer Immunology, Immunotherapy Type: main |
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