Food Allergy Prevalence in Two Population‐Based UK Cohorts Born 12 Years Apart.
| Title: | Food Allergy Prevalence in Two Population‐Based UK Cohorts Born 12 Years Apart. |
|---|---|
| Authors: | Fong, William, Pickett‐Nairne, Kaci, Venter, Manzi, Patil, Veeresh, Arshad, Syed Hasan, Roberts, Graham C., Dean, Tara, Kurukulaaratchy, Ramesh J., Venter, Carina |
| Source: | Clinical & Experimental Allergy; Feb2025, Vol. 55 Issue 2, p166-174, 9p |
| Subject Terms: | FOOD allergy, DISEASE prevalence, ALLERGIES, COHORT analysis, SCHOOL children |
| Geographic Terms: | UNITED Kingdom, ISLE of Wight (England) |
| Abstract: | Background: Adverse food reactions include food allergy (FA; immune‐mediated) and food intolerances (non‐immune‐mediated). FA are classified into IgE‐ and non‐IgE‐mediated FA. There is limited information available about changes in FA prevalence over time. Methods: Two cohorts of children were evaluated, born on the Isle of Wight (IOW) 12 years apart, the IOW birth cohort (IOWBC; 1989–1990) and the FA and Intolerance Research birth cohort (FAIRBC; 2001–2002). We compared the prevalence of parental reported reactions to foods (adverse food reactions), allergic sensitisation to foods and FA between the IOWBC and FAIRBC, at ages 1, 2, 3–4 and 10 years. FA included both IgE‐ and non‐IgE‐mediated FA. Results: Reported adverse reactions to food and sensitisation rates remained stable between the two cohorts. For example, FA at age 3–4 years was reported in 9.1% (95% CI: 7.5, 10.7) in IOWBC and 8.3% (95% CI: 6.5, 10.1) in FAIRBC (p = 0.57) and food sensitisation by skin prick test at age 3–4 years was found in 3.2% (95% CI: 2.1, 4.3) in IOWBC and 4.5% (95% CI: 2.9, 6.1) in FAIRBC (p = 0.20). Confirmed FA prevalence was lower in FAIRBC than IOWBC at ages 1, 2 and 3–4, but these differences were not significant after adjustment for multiple comparisons. For example, FA at age 3–4 years was confirmed in 5.0% (95% CI: 3.8, 6.2) in IOWBC and 3.0% (95% CI: 1.9, 4.2) in FAIRBC (p = 0.03, significance threshold after Bonferroni correction p < 0.004). Confirmed cow's milk allergy rate was higher in IOWBC than FAIRBC at 3 years (< 0.001) but not at other time points. Conclusion: Our data show no evidence of changes in rates of adverse reactions to foods, food sensitisation or food allergy during the first 10 years of life between two cohorts born in England in 1989–1990 and 2001–2002. [ABSTRACT FROM AUTHOR] |
| Copyright of Clinical & Experimental Allergy is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Complementary Index |
| FullText | Links: – Type: other Text: Availability: 0 CustomLinks: – Url: https://resolver.ebsco.com/c/xy5jbn/result?sid=EBSCO:edb&genre=article&issn=09547894&ISBN=&volume=55&issue=2&date=20250201&spage=166&pages=166-174&title=Clinical & Experimental Allergy&atitle=Food%20Allergy%20Prevalence%20in%20Two%20Population%E2%80%90Based%20UK%20Cohorts%20Born%2012%E2%80%89Years%20Apart.&aulast=Fong%2C%20William&id=DOI:10.1111/cea.14605 Name: Full Text Finder (for New FTF UI) (s8985755) Category: fullText Text: Find It @ SCU Libraries MouseOverText: Find It @ SCU Libraries |
|---|---|
| Header | DbId: edb DbLabel: Complementary Index An: 183914763 RelevancyScore: 1082 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 1082.12268066406 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Food Allergy Prevalence in Two Population‐Based UK Cohorts Born 12 Years Apart. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Fong%2C+William%22">Fong, William</searchLink><br /><searchLink fieldCode="AR" term="%22Pickett‐Nairne%2C+Kaci%22">Pickett‐Nairne, Kaci</searchLink><br /><searchLink fieldCode="AR" term="%22Venter%2C+Manzi%22">Venter, Manzi</searchLink><br /><searchLink fieldCode="AR" term="%22Patil%2C+Veeresh%22">Patil, Veeresh</searchLink><br /><searchLink fieldCode="AR" term="%22Arshad%2C+Syed+Hasan%22">Arshad, Syed Hasan</searchLink><br /><searchLink fieldCode="AR" term="%22Roberts%2C+Graham+C%2E%22">Roberts, Graham C.</searchLink><br /><searchLink fieldCode="AR" term="%22Dean%2C+Tara%22">Dean, Tara</searchLink><br /><searchLink fieldCode="AR" term="%22Kurukulaaratchy%2C+Ramesh+J%2E%22">Kurukulaaratchy, Ramesh J.</searchLink><br /><searchLink fieldCode="AR" term="%22Venter%2C+Carina%22">Venter, Carina</searchLink> – Name: TitleSource Label: Source Group: Src Data: Clinical & Experimental Allergy; Feb2025, Vol. 55 Issue 2, p166-174, 9p – Name: Subject Label: Subject Terms Group: Su Data: <searchLink fieldCode="DE" term="%22FOOD+allergy%22">FOOD allergy</searchLink><br /><searchLink fieldCode="DE" term="%22DISEASE+prevalence%22">DISEASE prevalence</searchLink><br /><searchLink fieldCode="DE" term="%22ALLERGIES%22">ALLERGIES</searchLink><br /><searchLink fieldCode="DE" term="%22COHORT+analysis%22">COHORT analysis</searchLink><br /><searchLink fieldCode="DE" term="%22SCHOOL+children%22">SCHOOL children</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22UNITED+Kingdom%22">UNITED Kingdom</searchLink><br /><searchLink fieldCode="DE" term="%22ISLE+of+Wight+%28England%29%22">ISLE of Wight (England)</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Background: Adverse food reactions include food allergy (FA; immune‐mediated) and food intolerances (non‐immune‐mediated). FA are classified into IgE‐ and non‐IgE‐mediated FA. There is limited information available about changes in FA prevalence over time. Methods: Two cohorts of children were evaluated, born on the Isle of Wight (IOW) 12 years apart, the IOW birth cohort (IOWBC; 1989–1990) and the FA and Intolerance Research birth cohort (FAIRBC; 2001–2002). We compared the prevalence of parental reported reactions to foods (adverse food reactions), allergic sensitisation to foods and FA between the IOWBC and FAIRBC, at ages 1, 2, 3–4 and 10 years. FA included both IgE‐ and non‐IgE‐mediated FA. Results: Reported adverse reactions to food and sensitisation rates remained stable between the two cohorts. For example, FA at age 3–4 years was reported in 9.1% (95% CI: 7.5, 10.7) in IOWBC and 8.3% (95% CI: 6.5, 10.1) in FAIRBC (p = 0.57) and food sensitisation by skin prick test at age 3–4 years was found in 3.2% (95% CI: 2.1, 4.3) in IOWBC and 4.5% (95% CI: 2.9, 6.1) in FAIRBC (p = 0.20). Confirmed FA prevalence was lower in FAIRBC than IOWBC at ages 1, 2 and 3–4, but these differences were not significant after adjustment for multiple comparisons. For example, FA at age 3–4 years was confirmed in 5.0% (95% CI: 3.8, 6.2) in IOWBC and 3.0% (95% CI: 1.9, 4.2) in FAIRBC (p = 0.03, significance threshold after Bonferroni correction p < 0.004). Confirmed cow's milk allergy rate was higher in IOWBC than FAIRBC at 3 years (< 0.001) but not at other time points. Conclusion: Our data show no evidence of changes in rates of adverse reactions to foods, food sensitisation or food allergy during the first 10 years of life between two cohorts born in England in 1989–1990 and 2001–2002. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Group: Ab Data: <i>Copyright of Clinical & Experimental Allergy is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://login.libproxy.scu.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edb&AN=183914763 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/cea.14605 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 9 StartPage: 166 Subjects: – SubjectFull: UNITED Kingdom Type: general – SubjectFull: ISLE of Wight (England) Type: general – SubjectFull: FOOD allergy Type: general – SubjectFull: DISEASE prevalence Type: general – SubjectFull: ALLERGIES Type: general – SubjectFull: COHORT analysis Type: general – SubjectFull: SCHOOL children Type: general Titles: – TitleFull: Food Allergy Prevalence in Two Population‐Based UK Cohorts Born 12 Years Apart. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Fong, William – PersonEntity: Name: NameFull: Pickett‐Nairne, Kaci – PersonEntity: Name: NameFull: Venter, Manzi – PersonEntity: Name: NameFull: Patil, Veeresh – PersonEntity: Name: NameFull: Arshad, Syed Hasan – PersonEntity: Name: NameFull: Roberts, Graham C. – PersonEntity: Name: NameFull: Dean, Tara – PersonEntity: Name: NameFull: Kurukulaaratchy, Ramesh J. – PersonEntity: Name: NameFull: Venter, Carina IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: Feb2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 09547894 Numbering: – Type: volume Value: 55 – Type: issue Value: 2 Titles: – TitleFull: Clinical & Experimental Allergy Type: main |
| ResultId | 1 |