Rare Variant of Spindle Cell Lipoma of the Lip: Utilizing Immunohistochemistry as an Essential Diagnostic Tool.
| Title: | Rare Variant of Spindle Cell Lipoma of the Lip: Utilizing Immunohistochemistry as an Essential Diagnostic Tool. |
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| Authors: | Doddawad, Vidya G., Patil, Karthikeya, Sanjay C. J., Shivananda S. |
| Source: | Oral & Maxillofacial Pathology Journal; Jul-Dec2024, Vol. 15 Issue 2, p274-279, 6p |
| Subject Terms: | DIAGNOSTIC immunohistochemistry, SURGICAL excision, SMOOTH muscle, LIPOMA, CD34 antigen |
| Abstract: | Introduction: The histopathological variant of lipoma identified as spindle cell lipoma invariably begins to develop deep within the skin in the back of the neck, upper back, or shoulder region. It develops seldomly in the oral cavity yet extremely frequently on the lip. Predominantly, these lesions manifest mostly as painless or slowly gaining masses. Case report: A 75-year-old woman had single swelling in the left lower lip which had existed there for four months. On a microscopic level, these tumors are well structured and represented in varied amounts of mature adipocytes, spindle cells, and irregular bundles of thick collagen fibres. The spindle cells are S-100 protein, desmin, and smooth muscle actin-negative whilst immunopositive to CD34. Treatment primarily involves local excision, and no reports of recurrence have been made. Conclusion: With a study of the available literature on diverse histological variants, differential diagnosis, and the adoption of IHC for diagnostic purposes, we present a rare case of spindle cell lipoma of the lip. [ABSTRACT FROM AUTHOR] |
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| Database: | Complementary Index |
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