Reply to: "Give Patients the Choice to Test for DPD Deficiency Before Fluoropyrimidine Chemotherapy," "Large-Scale DPD Testing Should Be More Than an Option," and "A Big Problem With a Feasible Solution, Not a Small Problem With a Complex Solution".
Title: | Reply to: "Give Patients the Choice to Test for DPD Deficiency Before Fluoropyrimidine Chemotherapy," "Large-Scale DPD Testing Should Be More Than an Option," and "A Big Problem With a Feasible Solution, Not a Small Problem With a Complex Solution". |
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Authors: | Tamraz, Bani, Venook, Alan P. |
Source: | JCO Oncology Practice; Feb2025, Vol. 21 Issue 2, p265-266, 2p |
Subject Terms: | INBORN errors of metabolism, CANCER chemotherapy, PHARMACOGENOMICS, FLUOROURACIL, GENOTYPES, SINGLE nucleotide polymorphisms, PATIENTS' attitudes |
Abstract: | The article focuses on clarifying misunderstandings and responding to critiques of a previous editorial regarding DPYD genotyping and fluoropyrimidine-related toxicities. Topics include the complexity and limitations of current DPYD testing, the rare occurrence of absolute DPYD deficiency, and the importance of patient and clinician choice in testing decisions. |
Database: | Complementary Index |
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Items | – Name: Title Label: Title Group: Ti Data: Reply to: "Give Patients the Choice to Test for DPD Deficiency Before Fluoropyrimidine Chemotherapy," "Large-Scale DPD Testing Should Be More Than an Option," and "A Big Problem With a Feasible Solution, Not a Small Problem With a Complex Solution". – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Tamraz%2C+Bani%22">Tamraz, Bani</searchLink><br /><searchLink fieldCode="AR" term="%22Venook%2C+Alan+P%2E%22">Venook, Alan P.</searchLink> – Name: TitleSource Label: Source Group: Src Data: JCO Oncology Practice; Feb2025, Vol. 21 Issue 2, p265-266, 2p – Name: Subject Label: Subject Terms Group: Su Data: <searchLink fieldCode="DE" term="%22INBORN+errors+of+metabolism%22">INBORN errors of metabolism</searchLink><br /><searchLink fieldCode="DE" term="%22CANCER+chemotherapy%22">CANCER chemotherapy</searchLink><br /><searchLink fieldCode="DE" term="%22PHARMACOGENOMICS%22">PHARMACOGENOMICS</searchLink><br /><searchLink fieldCode="DE" term="%22FLUOROURACIL%22">FLUOROURACIL</searchLink><br /><searchLink fieldCode="DE" term="%22GENOTYPES%22">GENOTYPES</searchLink><br /><searchLink fieldCode="DE" term="%22SINGLE+nucleotide+polymorphisms%22">SINGLE nucleotide polymorphisms</searchLink><br /><searchLink fieldCode="DE" term="%22PATIENTS'+attitudes%22">PATIENTS' attitudes</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: The article focuses on clarifying misunderstandings and responding to critiques of a previous editorial regarding DPYD genotyping and fluoropyrimidine-related toxicities. Topics include the complexity and limitations of current DPYD testing, the rare occurrence of absolute DPYD deficiency, and the importance of patient and clinician choice in testing decisions. |
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RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1200/OP-24-00923 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 2 StartPage: 265 Subjects: – SubjectFull: INBORN errors of metabolism Type: general – SubjectFull: CANCER chemotherapy Type: general – SubjectFull: PHARMACOGENOMICS Type: general – SubjectFull: FLUOROURACIL Type: general – SubjectFull: GENOTYPES Type: general – SubjectFull: SINGLE nucleotide polymorphisms Type: general – SubjectFull: PATIENTS' attitudes Type: general Titles: – TitleFull: Reply to: "Give Patients the Choice to Test for DPD Deficiency Before Fluoropyrimidine Chemotherapy," "Large-Scale DPD Testing Should Be More Than an Option," and "A Big Problem With a Feasible Solution, Not a Small Problem With a Complex Solution". Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tamraz, Bani – PersonEntity: Name: NameFull: Venook, Alan P. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: Feb2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 26881527 Numbering: – Type: volume Value: 21 – Type: issue Value: 2 Titles: – TitleFull: JCO Oncology Practice Type: main |
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