Antidiabetic medicinal plants from the Chenopodiaceae family: a comprehensive overview.

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Title: Antidiabetic medicinal plants from the Chenopodiaceae family: a comprehensive overview.
Authors: Cherrada, Nezar, Elkhalifa Chemsa, Ahmed, Gheraissa, Noura, Zaater, Abdelmalek, Benamor, Bilal, Ghania, Ahmed, Yassine, Bouras, Kaddour, Abdelbasset, Afzaal, Muhammad, Asghar, Aasma, Saeed, Farhan, Teferi Asres, Degnet
Source: International Journal of Food Properties; 2024, Vol. 27 Issue 1, p194-213, 20p
Subject Terms: ANIMAL models of diabetes, BLOOD sugar, MEDICINAL plants, BIOACTIVE compounds, CHENOPODIACEAE, INSULIN
Abstract: Diabetes is a chronic disease that has affected millions of people worldwide. The current treatments for diabetes, such as insulin therapy and oral medications, have limitations, including adverse effects and high costs. Therefore, there is a need for new and effective treatments for diabetes. Recent studies have shown that plants from the Chenopodiaceae family have anti-diabetic properties. In this study, we have identified 22 plants from the Chenopodiaceae family that have been reported to have anti-diabetic properties. These plants contain various bioactive compounds, such as flavonoids, alkaloids, and phenols that have been shown to have anti-diabetic effects. Some of these compounds can enhance insulin secretion, improve glucose uptake, and reduce blood glucose levels. The anti-diabetic properties of these plants have been investigated in vitro and in vivo studies, and the results are promising. Several of these plants have been shown to reduce blood glucose levels in animal models of diabetes significantly. Overall, the findings of this study suggest that plants from the Chenopodiaceae family have potential as safe and effective treatment options for diabetes. Further research is needed to fully understand these plants' mechanisms of action and safety profile. However, these findings provide a promising avenue for developing new anti-diabetic drugs from natural sources. Specifically, I've outlined three significant mechanisms: stimulation of insulin secretion, enhancement of glucose uptake, and inhibition of gluconeogenesis, all of which are attributed to the bioactive compounds found in Chenopodiaceae medicinal plants. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Food Properties is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Complementary Index
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  Data: Antidiabetic medicinal plants from the Chenopodiaceae family: a comprehensive overview.
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  Data: <searchLink fieldCode="AR" term="%22Cherrada%2C+Nezar%22">Cherrada, Nezar</searchLink><br /><searchLink fieldCode="AR" term="%22Elkhalifa+Chemsa%2C+Ahmed%22">Elkhalifa Chemsa, Ahmed</searchLink><br /><searchLink fieldCode="AR" term="%22Gheraissa%2C+Noura%22">Gheraissa, Noura</searchLink><br /><searchLink fieldCode="AR" term="%22Zaater%2C+Abdelmalek%22">Zaater, Abdelmalek</searchLink><br /><searchLink fieldCode="AR" term="%22Benamor%2C+Bilal%22">Benamor, Bilal</searchLink><br /><searchLink fieldCode="AR" term="%22Ghania%2C+Ahmed%22">Ghania, Ahmed</searchLink><br /><searchLink fieldCode="AR" term="%22Yassine%2C+Bouras%22">Yassine, Bouras</searchLink><br /><searchLink fieldCode="AR" term="%22Kaddour%2C+Abdelbasset%22">Kaddour, Abdelbasset</searchLink><br /><searchLink fieldCode="AR" term="%22Afzaal%2C+Muhammad%22">Afzaal, Muhammad</searchLink><br /><searchLink fieldCode="AR" term="%22Asghar%2C+Aasma%22">Asghar, Aasma</searchLink><br /><searchLink fieldCode="AR" term="%22Saeed%2C+Farhan%22">Saeed, Farhan</searchLink><br /><searchLink fieldCode="AR" term="%22Teferi+Asres%2C+Degnet%22">Teferi Asres, Degnet</searchLink>
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  Data: International Journal of Food Properties; 2024, Vol. 27 Issue 1, p194-213, 20p
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  Data: <searchLink fieldCode="DE" term="%22ANIMAL+models+of+diabetes%22">ANIMAL models of diabetes</searchLink><br /><searchLink fieldCode="DE" term="%22BLOOD+sugar%22">BLOOD sugar</searchLink><br /><searchLink fieldCode="DE" term="%22MEDICINAL+plants%22">MEDICINAL plants</searchLink><br /><searchLink fieldCode="DE" term="%22BIOACTIVE+compounds%22">BIOACTIVE compounds</searchLink><br /><searchLink fieldCode="DE" term="%22CHENOPODIACEAE%22">CHENOPODIACEAE</searchLink><br /><searchLink fieldCode="DE" term="%22INSULIN%22">INSULIN</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Diabetes is a chronic disease that has affected millions of people worldwide. The current treatments for diabetes, such as insulin therapy and oral medications, have limitations, including adverse effects and high costs. Therefore, there is a need for new and effective treatments for diabetes. Recent studies have shown that plants from the Chenopodiaceae family have anti-diabetic properties. In this study, we have identified 22 plants from the Chenopodiaceae family that have been reported to have anti-diabetic properties. These plants contain various bioactive compounds, such as flavonoids, alkaloids, and phenols that have been shown to have anti-diabetic effects. Some of these compounds can enhance insulin secretion, improve glucose uptake, and reduce blood glucose levels. The anti-diabetic properties of these plants have been investigated in vitro and in vivo studies, and the results are promising. Several of these plants have been shown to reduce blood glucose levels in animal models of diabetes significantly. Overall, the findings of this study suggest that plants from the Chenopodiaceae family have potential as safe and effective treatment options for diabetes. Further research is needed to fully understand these plants' mechanisms of action and safety profile. However, these findings provide a promising avenue for developing new anti-diabetic drugs from natural sources. Specifically, I've outlined three significant mechanisms: stimulation of insulin secretion, enhancement of glucose uptake, and inhibition of gluconeogenesis, all of which are attributed to the bioactive compounds found in Chenopodiaceae medicinal plants. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label:
  Group: Ab
  Data: <i>Copyright of International Journal of Food Properties is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1080/10942912.2023.2301576
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      – Code: eng
        Text: English
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        PageCount: 20
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      – SubjectFull: ANIMAL models of diabetes
        Type: general
      – SubjectFull: BLOOD sugar
        Type: general
      – SubjectFull: MEDICINAL plants
        Type: general
      – SubjectFull: BIOACTIVE compounds
        Type: general
      – SubjectFull: CHENOPODIACEAE
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      – SubjectFull: INSULIN
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              M: 12
              Text: 2024
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