Investigating the effectiveness of web‐based HIV self‐test distribution and linkage to HIV treatment and PrEP among groups at elevated risk of HIV in Viet Nam provinces: a mixed‐methods analysis of implementation from pilot to scale‐up
| Title: | Investigating the effectiveness of web‐based HIV self‐test distribution and linkage to HIV treatment and PrEP among groups at elevated risk of HIV in Viet Nam provinces: a mixed‐methods analysis of implementation from pilot to scale‐up |
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| Authors: | Nguyen, Van Thi Thuy, Dunkley, Yasmin, Son, Vo Hai, Choko, Augustine T., Huong, Phan Thi Thu, Manh, Pham Duc, Truong, Truong Minh, Truc, Huynh Minh, Giang, Dap Thanh, Tung, Le Thanh, Hoa, Van Dinh, Baggaley, Rachel, Johnson, Cheryl |
| Source: | Journal of the International AIDS Society; Jul2024 Supplement 1, Vol. 27, p1-13, 13p |
| Subject Terms: | PRE-exposure prophylaxis, HIV testing kits, HIV, PATIENT self-monitoring, ANTIRETROVIRAL agents, THEMATIC analysis |
| Geographic Terms: | VIETNAM |
| Abstract: | Introduction: In Viet Nam, key populations (KPs) face barriers accessing HIV services. Virtual platforms can be leveraged to increase access for KPs, including for HIV self‐testing (HIVST). This study compares reach and effectiveness of a web‐based HIVST intervention from pilot to scale‐up in Viet Nam. Methods: A mixed‐methods explanatory sequential design used cross‐sectional and thematic analysis. The pilot launched in Can Tho in November 2020, followed by Hanoi and Nghe An in April 2021. Scale‐up included Can Tho and Nghe An, with 21 novel provinces from April to December 2022. After risk assessment, participants registered on the website, receiving HIVST (OraQuick®) by courier, peer educator or self‐pick‐up. Test result reporting and completing satisfaction surveys were encouraged. Intervention reach was measured through numbers accessing the testing, disaggregated by demographics, and proportion of individuals reporting self‐testing post‐registration. Effectiveness was measured through numbers reporting self‐test results, testing positive and linking to care, and testing negative and using HIVST to manage pre‐exposure prophylaxis (PrEP) use. Thematic content analysis of free‐text responses from the satisfaction survey synthesized quantitative outcomes. Results: In total, 17,589 participants registered on the HIVST website; 11,332 individuals ordered 13,334 tests. Participants were generally young, aged <25 years (4309/11,332, 38.0%), male (9418/11,332, 83.1%) and men who have sex with men (6437/11,332, 56.8%). Nearly half were first‐time testers (5069/11,332, 44.9%). Scale‐up participants were two times more likely to be assigned female at birth (scale‐up; 1595/8436, 18.9% compared to pilot; 392/3727, 10.5%, p < 0.001). Fewer test results were reported in scale‐up compared with pilot (pilot: 3129/4140, 75.6%, scale‐up: 5811/9194, 63.2%, p < 0.001). 6.3% of all tests were reactive (pilot: 176/3129, 5.6% reactive compared to scale‐up: 385/5811, 6.6% reactive, p = 0.063); of which most linked to care (509/522, 97.5%). One‐fifth of participants with a negative test initiated or continued PrEP (pilot; 19.8%, scale‐up; 18.5%, p = 0.124). Thematic analysis suggested that community delivery models increased programmatic reach. Live chat may also be a suitable proxy for staff support to increase result reporting. Conclusions: Web‐based self‐testing in Viet Nam reached people at elevated risk of HIV, facilitating uptake of anti‐retroviral treatment and direct linkage to PrEP initiations. Further innovations such as the use of social‐network testing services and incorporating features powered by artificial intelligence could increase the effectiveness and efficiency of the approach. [ABSTRACT FROM AUTHOR] |
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| Database: | Complementary Index |
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| Items | – Name: Title Label: Title Group: Ti Data: Investigating the effectiveness of web‐based HIV self‐test distribution and linkage to HIV treatment and PrEP among groups at elevated risk of HIV in Viet Nam provinces: a mixed‐methods analysis of implementation from pilot to scale‐up – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Nguyen%2C+Van+Thi+Thuy%22">Nguyen, Van Thi Thuy</searchLink><br /><searchLink fieldCode="AR" term="%22Dunkley%2C+Yasmin%22">Dunkley, Yasmin</searchLink><br /><searchLink fieldCode="AR" term="%22Son%2C+Vo+Hai%22">Son, Vo Hai</searchLink><br /><searchLink fieldCode="AR" term="%22Choko%2C+Augustine+T%2E%22">Choko, Augustine T.</searchLink><br /><searchLink fieldCode="AR" term="%22Huong%2C+Phan+Thi+Thu%22">Huong, Phan Thi Thu</searchLink><br /><searchLink fieldCode="AR" term="%22Manh%2C+Pham+Duc%22">Manh, Pham Duc</searchLink><br /><searchLink fieldCode="AR" term="%22Truong%2C+Truong+Minh%22">Truong, Truong Minh</searchLink><br /><searchLink fieldCode="AR" term="%22Truc%2C+Huynh+Minh%22">Truc, Huynh Minh</searchLink><br /><searchLink fieldCode="AR" term="%22Giang%2C+Dap+Thanh%22">Giang, Dap Thanh</searchLink><br /><searchLink fieldCode="AR" term="%22Tung%2C+Le+Thanh%22">Tung, Le Thanh</searchLink><br /><searchLink fieldCode="AR" term="%22Hoa%2C+Van+Dinh%22">Hoa, Van Dinh</searchLink><br /><searchLink fieldCode="AR" term="%22Baggaley%2C+Rachel%22">Baggaley, Rachel</searchLink><br /><searchLink fieldCode="AR" term="%22Johnson%2C+Cheryl%22">Johnson, Cheryl</searchLink> – Name: TitleSource Label: Source Group: Src Data: Journal of the International AIDS Society; Jul2024 Supplement 1, Vol. 27, p1-13, 13p – Name: Subject Label: Subject Terms Group: Su Data: <searchLink fieldCode="DE" term="%22PRE-exposure+prophylaxis%22">PRE-exposure prophylaxis</searchLink><br /><searchLink fieldCode="DE" term="%22HIV+testing+kits%22">HIV testing kits</searchLink><br /><searchLink fieldCode="DE" term="%22HIV%22">HIV</searchLink><br /><searchLink fieldCode="DE" term="%22PATIENT+self-monitoring%22">PATIENT self-monitoring</searchLink><br /><searchLink fieldCode="DE" term="%22ANTIRETROVIRAL+agents%22">ANTIRETROVIRAL agents</searchLink><br /><searchLink fieldCode="DE" term="%22THEMATIC+analysis%22">THEMATIC analysis</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22VIETNAM%22">VIETNAM</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Introduction: In Viet Nam, key populations (KPs) face barriers accessing HIV services. Virtual platforms can be leveraged to increase access for KPs, including for HIV self‐testing (HIVST). This study compares reach and effectiveness of a web‐based HIVST intervention from pilot to scale‐up in Viet Nam. Methods: A mixed‐methods explanatory sequential design used cross‐sectional and thematic analysis. The pilot launched in Can Tho in November 2020, followed by Hanoi and Nghe An in April 2021. Scale‐up included Can Tho and Nghe An, with 21 novel provinces from April to December 2022. After risk assessment, participants registered on the website, receiving HIVST (OraQuick®) by courier, peer educator or self‐pick‐up. Test result reporting and completing satisfaction surveys were encouraged. Intervention reach was measured through numbers accessing the testing, disaggregated by demographics, and proportion of individuals reporting self‐testing post‐registration. Effectiveness was measured through numbers reporting self‐test results, testing positive and linking to care, and testing negative and using HIVST to manage pre‐exposure prophylaxis (PrEP) use. Thematic content analysis of free‐text responses from the satisfaction survey synthesized quantitative outcomes. Results: In total, 17,589 participants registered on the HIVST website; 11,332 individuals ordered 13,334 tests. Participants were generally young, aged <25 years (4309/11,332, 38.0%), male (9418/11,332, 83.1%) and men who have sex with men (6437/11,332, 56.8%). Nearly half were first‐time testers (5069/11,332, 44.9%). Scale‐up participants were two times more likely to be assigned female at birth (scale‐up; 1595/8436, 18.9% compared to pilot; 392/3727, 10.5%, p < 0.001). Fewer test results were reported in scale‐up compared with pilot (pilot: 3129/4140, 75.6%, scale‐up: 5811/9194, 63.2%, p < 0.001). 6.3% of all tests were reactive (pilot: 176/3129, 5.6% reactive compared to scale‐up: 385/5811, 6.6% reactive, p = 0.063); of which most linked to care (509/522, 97.5%). One‐fifth of participants with a negative test initiated or continued PrEP (pilot; 19.8%, scale‐up; 18.5%, p = 0.124). Thematic analysis suggested that community delivery models increased programmatic reach. Live chat may also be a suitable proxy for staff support to increase result reporting. Conclusions: Web‐based self‐testing in Viet Nam reached people at elevated risk of HIV, facilitating uptake of anti‐retroviral treatment and direct linkage to PrEP initiations. Further innovations such as the use of social‐network testing services and incorporating features powered by artificial intelligence could increase the effectiveness and efficiency of the approach. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Group: Ab Data: <i>Copyright of Journal of the International AIDS Society is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/jia2.26264 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 13 StartPage: 1 Subjects: – SubjectFull: VIETNAM Type: general – SubjectFull: PRE-exposure prophylaxis Type: general – SubjectFull: HIV testing kits Type: general – SubjectFull: HIV Type: general – SubjectFull: PATIENT self-monitoring Type: general – SubjectFull: ANTIRETROVIRAL agents Type: general – SubjectFull: THEMATIC analysis Type: general Titles: – TitleFull: Investigating the effectiveness of web‐based HIV self‐test distribution and linkage to HIV treatment and PrEP among groups at elevated risk of HIV in Viet Nam provinces: a mixed‐methods analysis of implementation from pilot to scale‐up Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Nguyen, Van Thi Thuy – PersonEntity: Name: NameFull: Dunkley, Yasmin – PersonEntity: Name: NameFull: Son, Vo Hai – PersonEntity: Name: NameFull: Choko, Augustine T. – PersonEntity: Name: NameFull: Huong, Phan Thi Thu – PersonEntity: Name: NameFull: Manh, Pham Duc – PersonEntity: Name: NameFull: Truong, Truong Minh – PersonEntity: Name: NameFull: Truc, Huynh Minh – PersonEntity: Name: NameFull: Giang, Dap Thanh – PersonEntity: Name: NameFull: Tung, Le Thanh – PersonEntity: Name: NameFull: Hoa, Van Dinh – PersonEntity: Name: NameFull: Baggaley, Rachel – PersonEntity: Name: NameFull: Johnson, Cheryl IsPartOfRelationships: – BibEntity: Dates: – D: 02 M: 07 Text: Jul2024 Supplement 1 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 17582652 Numbering: – Type: volume Value: 27 Titles: – TitleFull: Journal of the International AIDS Society Type: main |
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