Do stroke services still show sex differences? A multicenter study.

Bibliographic Details
Title: Do stroke services still show sex differences? A multicenter study.
Authors: Nahas, Nevine El, Shokri, Hossam, Roushdy, Tamer, Dawood, Noha, Zaki, Amr, Farhoudi, Mehdi, Hokmabadi, Elyar Sadeghi, Al Hashmi, Amal, Brola, Waldemar, Kosno, Krystian, Falup-Pecurariu, Cristian, Ciopleias, Bogdan, Montaner, Joan, Pérez-Sánchez, Soledad, Mittal, Manoj, Dowd, Kandis, Banke, Annie, Vigilante, Nicholas, Siegler, James, Ozdemir, Atilla Ozcan
Source: Neurological Sciences; Mar2024, Vol. 45 Issue 3, p1097-1108, 12p
Subject Terms: SEX factors in disease, STROKE, STROKE units, ISCHEMIC stroke
Abstract: Background: The issue of sex differences in stroke has gained concern in the past few years. However, multicenter studies are still required in this field. This study explores sex variation in a large number of patients and compares stroke characteristics among women in different age groups and across different countries. Methods: This multicenter retrospective cross-sectional study aimed to compare sexes regarding risk factors, stroke severity, quality of services, and stroke outcome. Moreover, conventional risk factors in women according to age groups and among different countries were studied. Results: Eighteen thousand six hundred fifty-nine patients from 9 countries spanning 4 continents were studied. The number of women was significantly lower than men, with older age, more prevalence of AF, hypertension, and dyslipidemia. Ischemic stroke was more severe in women, with worse outcomes among women (p: < 0.0001), although the time to treatment was shorter. Bridging that was more frequent in women (p:0.002). Analyzing only women: ischemic stroke was more frequent among the older, while hemorrhage and TIA prevailed in the younger and stroke of undetermined etiology. Comparison between countries showed differences in age, risk factors, type of stroke, and management. Conclusion: We observed sex differences in risk factors, stroke severity, and outcome in our population. However, access to revascularization was in favor of women. [ABSTRACT FROM AUTHOR]
Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Neurological Sciences; Mar2024, Vol. 45 Issue 3, p1097-1108, 12p
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22SEX+factors+in+disease%22&quot;&gt;SEX factors in disease&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22STROKE%22&quot;&gt;STROKE&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22STROKE+units%22&quot;&gt;STROKE units&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22ISCHEMIC+stroke%22&quot;&gt;ISCHEMIC stroke&lt;/searchLink&gt;
– Name: Abstract
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  Data: Background: The issue of sex differences in stroke has gained concern in the past few years. However, multicenter studies are still required in this field. This study explores sex variation in a large number of patients and compares stroke characteristics among women in different age groups and across different countries. Methods: This multicenter retrospective cross-sectional study aimed to compare sexes regarding risk factors, stroke severity, quality of services, and stroke outcome. Moreover, conventional risk factors in women according to age groups and among different countries were studied. Results: Eighteen thousand six hundred fifty-nine patients from 9 countries spanning 4 continents were studied. The number of women was significantly lower than men, with older age, more prevalence of AF, hypertension, and dyslipidemia. Ischemic stroke was more severe in women, with worse outcomes among women (p: &lt; 0.0001), although the time to treatment was shorter. Bridging that was more frequent in women (p:0.002). Analyzing only women: ischemic stroke was more frequent among the older, while hemorrhage and TIA prevailed in the younger and stroke of undetermined etiology. Comparison between countries showed differences in age, risk factors, type of stroke, and management. Conclusion: We observed sex differences in risk factors, stroke severity, and outcome in our population. However, access to revascularization was in favor of women. [ABSTRACT FROM AUTHOR]
– Name: Abstract
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  Data: &lt;i&gt;Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder&#39;s express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1007/s10072-023-07026-x
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