The Influence of Early Onset Preeclampsia on Perinatal Red Blood Cell Characteristics of Neonates.
| Title: | The Influence of Early Onset Preeclampsia on Perinatal Red Blood Cell Characteristics of Neonates. |
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| Authors: | Sandor, Barbara, Csiszar, Beata, Galos, Gergely, Funke, Simone, Kevey, Dora Kinga, Meggyes, Matyas, Szereday, Laszlo, Toth, Kalman |
| Source: | International Journal of Molecular Sciences; May2023, Vol. 24 Issue 10, p8496, 13p |
| Subject Terms: | HEMORHEOLOGY, ERYTHROCYTES, BLOOD viscosity, NEWBORN infants, PREECLAMPSIA, CORD blood |
| Abstract: | Preeclampsia is the leading cause of complicated neonatal adaptation. The present investigation aimed to study the hemorheological factors during the early perinatal period (cord blood, 24 and 72 h after delivery) in newborns of early-onset preeclamptic mothers (n = 13) and healthy neonates (n = 17). Hematocrit, plasma, and whole blood viscosity (WBV), red blood cell (RBC) aggregation, and deformability were investigated. There were no significant differences in hematocrit. WBV was significantly lower in preterm neonates at birth than in the term 24 and 72 h samples. Plasma viscosity was significantly lower in preterm neonates' cord blood than in healthy controls. RBC aggregation parameters were significantly lower in preterm newborns' cord blood than in term neonates' cord blood 24 and 72 h samples. RBC elongation indices were significantly lower in the term group than in preterm neonates 72 h' sample at the high and middle shear stress range. Changes in the hemorheological parameters, especially RBC aggregation properties, refer to better microcirculation of preterm neonates at birth, which could be an adaptation mechanism to the impaired uteroplacental microcirculation in preeclampsia. [ABSTRACT FROM AUTHOR] |
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| Database: | Complementary Index |
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