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Time trends in depression prevalence among Swedish 85-year-olds: repeated cross-sectional population-based studies in 1986, 2008, and 2015.

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Title: Time trends in depression prevalence among Swedish 85-year-olds: repeated cross-sectional population-based studies in 1986, 2008, and 2015.
Authors: Jonson, Mattias, Sigström, Robert, Hedna, Khedidja, Rydberg Sterner, Therese, Falk Erhag, Hanna, Wetterberg, Hanna, Fässberg, Madeleine Mellqvist, Waern, Margda, Skoog, Ingmar
Source: Psychological Medicine; Apr2023, Vol. 53 Issue 6, p2456-2465, 10p
Subject Terms: MENTAL depression risk factors, PSYCHIATRIC drugs, CONFIDENCE intervals, CROSS-sectional method, INTERVIEWING, PSYCHOLOGICAL tests, COMPARATIVE studies, MENTAL depression, DISEASE prevalence, DESCRIPTIVE statistics, RESEARCH funding, CLASSIFICATION of mental disorders, SOCIODEMOGRAPHIC factors, ODDS ratio, OLD age
Geographic Terms: SWEDEN
Abstract: Background: Octogenarians of today are better educated, and physically and cognitively healthier, than earlier born cohorts. Less is known about time trends in mental health in this age group. We aimed to study time trends in the prevalence of depression and psychotropic drug use among Swedish 85-year-olds. Methods: We derived data from interviews with 85-year-olds in 1986–1987 (N = 348), 2008–2010 (N = 433) and 2015–17 (N = 321). Depression diagnoses were made according to the Diagnostic and Statistical Manual of Mental Disorders. Symptom burden was assessed with the Montgomery-Åsberg Depression Rating Scale (MADRS). Information on psychotropic drug use, sociodemographic, and health-related factors were collected during the interviews. Results: The prevalence of major depression was lower in 2015–2017 (4.7%, p < 0.001) and 2008–2010 (6.9%, p = 0.010) compared to 1986–1987 (12.4%). The prevalence of minor depression was lower in 2015–2017 (8.1%) compared to 2008–2010 (16.2%, p = 0.001) and 1986–1987 (17.8%, p < 0.001). Mean MADRS score decreased from 8.0 in 1986–1987 to 6.5 in 2008–2010, and 5.1 in 2015–2017 (p < 0.001). The reduced prevalence of depression was not explained by changes in sociodemographic and health-related risk factors for depression. While psychoactive drug use was observed in a third of the participants in each cohort, drug type changed over time (increased use of antidepressants and decreased use of anxiolytics and antipsychotics). Conclusions: The prevalence of depression in octogenarians has declined during the past decades. The decline was not explained by changes in known risk factors for depression. The present study cannot answer whether changed prescription patterns of psychoactive drugs have contributed to the decline. [ABSTRACT FROM AUTHOR]
Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Time trends in depression prevalence among Swedish 85-year-olds: repeated cross-sectional population-based studies in 1986, 2008, and 2015.
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  Data: Psychological Medicine; Apr2023, Vol. 53 Issue 6, p2456-2465, 10p
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– Name: Abstract
  Label: Abstract
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  Data: Background: Octogenarians of today are better educated, and physically and cognitively healthier, than earlier born cohorts. Less is known about time trends in mental health in this age group. We aimed to study time trends in the prevalence of depression and psychotropic drug use among Swedish 85-year-olds. Methods: We derived data from interviews with 85-year-olds in 1986–1987 (N = 348), 2008–2010 (N = 433) and 2015–17 (N = 321). Depression diagnoses were made according to the Diagnostic and Statistical Manual of Mental Disorders. Symptom burden was assessed with the Montgomery-&#197;sberg Depression Rating Scale (MADRS). Information on psychotropic drug use, sociodemographic, and health-related factors were collected during the interviews. Results: The prevalence of major depression was lower in 2015–2017 (4.7%, p &lt; 0.001) and 2008–2010 (6.9%, p = 0.010) compared to 1986–1987 (12.4%). The prevalence of minor depression was lower in 2015–2017 (8.1%) compared to 2008–2010 (16.2%, p = 0.001) and 1986–1987 (17.8%, p &lt; 0.001). Mean MADRS score decreased from 8.0 in 1986–1987 to 6.5 in 2008–2010, and 5.1 in 2015–2017 (p &lt; 0.001). The reduced prevalence of depression was not explained by changes in sociodemographic and health-related risk factors for depression. While psychoactive drug use was observed in a third of the participants in each cohort, drug type changed over time (increased use of antidepressants and decreased use of anxiolytics and antipsychotics). Conclusions: The prevalence of depression in octogenarians has declined during the past decades. The decline was not explained by changes in known risk factors for depression. The present study cannot answer whether changed prescription patterns of psychoactive drugs have contributed to the decline. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label:
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  Data: &lt;i&gt;Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder&#39;s express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1017/S0033291721004335
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      – Code: eng
        Text: English
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        PageCount: 10
        StartPage: 2456
    Subjects:
      – SubjectFull: SWEDEN
        Type: general
      – SubjectFull: MENTAL depression risk factors
        Type: general
      – SubjectFull: PSYCHIATRIC drugs
        Type: general
      – SubjectFull: CONFIDENCE intervals
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      – SubjectFull: CROSS-sectional method
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      – SubjectFull: INTERVIEWING
        Type: general
      – SubjectFull: PSYCHOLOGICAL tests
        Type: general
      – SubjectFull: COMPARATIVE studies
        Type: general
      – SubjectFull: MENTAL depression
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              Text: Apr2023
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