Academic Journal
View in EDS

Infection of C. elegans by Haptoglossa Species Reveals Shared Features in the Host Response to Oomycete Detection.

Bibliographic Details
Title: Infection of C. elegans by Haptoglossa Species Reveals Shared Features in the Host Response to Oomycete Detection.
Authors: Grover, Manish, Fasseas, Michael K., Essmann, Clara, Liu, Kenneth, Braendle, Christian, Félix, Marie-Anne, Glockling, Sally L., Barkoulas, Michalis
Source: Frontiers in Cellular & Infection Microbiology; 10/14/2021, Vol. 11, p1-12, 12p
Subject Terms: OOMYCETES, CAENORHABDITIS elegans, SPECIES, PHYTOPATHOGENIC microorganisms, ELECTRON microscopy, INFECTION
Abstract: Oomycetes are a group of eukaryotic organisms that includes many important pathogens of animals and plants. Within this group, the Haptoglossa genus is characterised by the presence of specialised gun cells carrying a harpoon-like infection apparatus. While several Haptoglossa pathogens have been morphologically described, there are currently no host systems developed to study the infection process or host responses in the lab. In this study, we report that Haptoglossa species are potent natural pathogens of Caenorhabditis nematodes. Using electron microscopy, we characterise the infection process in C. elegans and demonstrate that the oomycete causes excessive tissue degradation upon entry in the body cavity, whilst leaving the host cuticle intact. We also report that the host transcriptional response to Haptoglossa infection shares similarities with the response against the oomycete Myzocytiopsis humicola , a key example of which is the induction of chitinase-like (chil) genes in the hypodermis. We demonstrate that this shared feature of the host response can be mounted by pathogen detection without any infection, as previously shown for M. humicola. These results highlight similarities in the nematode immune response to natural infection by phylogenetically distinct oomycetes. [ABSTRACT FROM AUTHOR]
Copyright of Frontiers in Cellular & Infection Microbiology is the property of Frontiers Media S.A. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Complementary Index
FullText Text:
  Availability: 0
CustomLinks:
  – Url: https://resolver.ebsco.com/c/xy5jbn/result?sid=EBSCO:edb&genre=article&issn=22352988&ISBN=&volume=11&issue=&date=20211014&spage=1&pages=1-12&title=Frontiers in Cellular & Infection Microbiology&atitle=Infection%20of%20C.%20elegans%20by%20Haptoglossa%20Species%20Reveals%20Shared%20Features%20in%20the%20Host%20Response%20to%20Oomycete%20Detection.&aulast=Grover%2C%20Manish&id=DOI:10.3389/fcimb.2021.733094
    Name: Full Text Finder (for New FTF UI) (s8985755)
    Category: fullText
    Text: Find It @ SCU Libraries
    MouseOverText: Find It @ SCU Libraries
Header DbId: edb
DbLabel: Complementary Index
An: 153034662
RelevancyScore: 925
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 925.494934082031
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Infection of C. elegans by Haptoglossa Species Reveals Shared Features in the Host Response to Oomycete Detection.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Grover%2C+Manish%22">Grover, Manish</searchLink><br /><searchLink fieldCode="AR" term="%22Fasseas%2C+Michael+K%2E%22">Fasseas, Michael K.</searchLink><br /><searchLink fieldCode="AR" term="%22Essmann%2C+Clara%22">Essmann, Clara</searchLink><br /><searchLink fieldCode="AR" term="%22Liu%2C+Kenneth%22">Liu, Kenneth</searchLink><br /><searchLink fieldCode="AR" term="%22Braendle%2C+Christian%22">Braendle, Christian</searchLink><br /><searchLink fieldCode="AR" term="%22Félix%2C+Marie-Anne%22">Félix, Marie-Anne</searchLink><br /><searchLink fieldCode="AR" term="%22Glockling%2C+Sally+L%2E%22">Glockling, Sally L.</searchLink><br /><searchLink fieldCode="AR" term="%22Barkoulas%2C+Michalis%22">Barkoulas, Michalis</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: Frontiers in Cellular & Infection Microbiology; 10/14/2021, Vol. 11, p1-12, 12p
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22OOMYCETES%22">OOMYCETES</searchLink><br /><searchLink fieldCode="DE" term="%22CAENORHABDITIS+elegans%22">CAENORHABDITIS elegans</searchLink><br /><searchLink fieldCode="DE" term="%22SPECIES%22">SPECIES</searchLink><br /><searchLink fieldCode="DE" term="%22PHYTOPATHOGENIC+microorganisms%22">PHYTOPATHOGENIC microorganisms</searchLink><br /><searchLink fieldCode="DE" term="%22ELECTRON+microscopy%22">ELECTRON microscopy</searchLink><br /><searchLink fieldCode="DE" term="%22INFECTION%22">INFECTION</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Oomycetes are a group of eukaryotic organisms that includes many important pathogens of animals and plants. Within this group, the Haptoglossa genus is characterised by the presence of specialised gun cells carrying a harpoon-like infection apparatus. While several Haptoglossa pathogens have been morphologically described, there are currently no host systems developed to study the infection process or host responses in the lab. In this study, we report that Haptoglossa species are potent natural pathogens of Caenorhabditis nematodes. Using electron microscopy, we characterise the infection process in C. elegans and demonstrate that the oomycete causes excessive tissue degradation upon entry in the body cavity, whilst leaving the host cuticle intact. We also report that the host transcriptional response to Haptoglossa infection shares similarities with the response against the oomycete Myzocytiopsis humicola , a key example of which is the induction of chitinase-like (chil) genes in the hypodermis. We demonstrate that this shared feature of the host response can be mounted by pathogen detection without any infection, as previously shown for M. humicola. These results highlight similarities in the nematode immune response to natural infection by phylogenetically distinct oomycetes. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label:
  Group: Ab
  Data: <i>Copyright of Frontiers in Cellular & Infection Microbiology is the property of Frontiers Media S.A. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://login.libproxy.scu.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edb&AN=153034662
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3389/fcimb.2021.733094
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 12
        StartPage: 1
    Subjects:
      – SubjectFull: OOMYCETES
        Type: general
      – SubjectFull: CAENORHABDITIS elegans
        Type: general
      – SubjectFull: SPECIES
        Type: general
      – SubjectFull: PHYTOPATHOGENIC microorganisms
        Type: general
      – SubjectFull: ELECTRON microscopy
        Type: general
      – SubjectFull: INFECTION
        Type: general
    Titles:
      – TitleFull: Infection of C. elegans by Haptoglossa Species Reveals Shared Features in the Host Response to Oomycete Detection.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Grover, Manish
      – PersonEntity:
          Name:
            NameFull: Fasseas, Michael K.
      – PersonEntity:
          Name:
            NameFull: Essmann, Clara
      – PersonEntity:
          Name:
            NameFull: Liu, Kenneth
      – PersonEntity:
          Name:
            NameFull: Braendle, Christian
      – PersonEntity:
          Name:
            NameFull: Félix, Marie-Anne
      – PersonEntity:
          Name:
            NameFull: Glockling, Sally L.
      – PersonEntity:
          Name:
            NameFull: Barkoulas, Michalis
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 14
              M: 10
              Text: 10/14/2021
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-print
              Value: 22352988
          Numbering:
            – Type: volume
              Value: 11
          Titles:
            – TitleFull: Frontiers in Cellular & Infection Microbiology
              Type: main
ResultId 1