A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models.

Bibliographic Details
Title: A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models.
Authors: Yiming Zhou1,2, Castonguay, Philip1,2, Sidhom, Eriene-Heidi1,2, Clark, Abbe R.1,2, Dvela-Levitt, Moran1,2, Sookyung Kim1,2, Sieber, Jonas1,2, Wieder, Nicolas1,2, Ji Yong Jung1,3, Andreeva, Svetlana1, Reichardt, Jana1, Dubois, Frank1, Hoffmann, Sigrid C.4, Basgen, John M.5, Montesinos, Mónica S.1,2, Weins, Astrid1,6, Johnson, Ashley C.7, Lander, Eric S.2, Garrett, Michael R.7, Hopkins, Corey R.8
Source: Science; 12/8/2017, Vol. 358 Issue 6368, p1332-1336, 5p
Database: Applied Science & Technology Source
More Details
ISSN:00368075
DOI:10.1126/science.aal4178
Published in:Science
Language:English