Epidemiology of obstructive sleep apnoea syndrome in Chinese children: a two-phase community study.

Bibliographic Details
Title: Epidemiology of obstructive sleep apnoea syndrome in Chinese children: a two-phase community study.
Authors: Albert M Li1
Source: Thorax. Nov2010, Vol. 65 Issue 11, p991-997. 7p.
Subject Terms: *SLEEP apnea syndromes, *CHILDREN'S health, *DISEASE prevalence, *SLEEP disorders in children, *POLYSOMNOGRAPHY, *CHINESE people, *DISEASE risk factors
Abstract: OBJECTIVE: To determine the prevalence and risk factors of obstructive sleep apnoea syndrome (OSAS) in Chinese children using a two-phase community-based study design. METHODS: Children from 13 primary schools were randomly recruited. A validated OSAS screening questionnaire was completed by their parents. Children at high risk of OSAS and a randomly chosen low-risk group were invited to undergo overnight polysomnographic study and clinical examination. The the sex-specific prevalence rate was measured using different cutoffs (obstructive apnoea hypopnoea index ≥1, ≥1.5, ≥3 and ≥5 and obstructive apnoea index ≥5) and risk factors associated with OSAS were evaluated with logistic regression. RESULTS: 6447 completed questionnaires were returned (out of 9172 questionnaires; 70.3%). 586 children (9.1%; 405 boys and 181 girls) children belonged to the high-risk group. A total of 619 (410 and 209 from the high and low-risk group, respectively) subjects underwent overnight polysomnagraphy. Depending on the cutoffs, the prevalence rate of childhood OSAS varied from 4.8% to 40.3%. Using the International Criteria of Sleep Disorders version II, the OSAS prevalence for boys and girls was 5.8% and 3.8%, respectively. Male gender, body mass index z-score and increased adenoid and tonsil size were independently associated with OSAS. CONCLUSIONS: The prevalence rate of OSAS in children was contingent on the cutoff used. The inclusion of symptoms as a part of the diagnostic criteria greatly reduced the prevalence. A further prospective and outcome study is needed to define a clinically significant diagnostic cutoff for childhood OSAS. [ABSTRACT FROM AUTHOR]
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  Data: Epidemiology of obstructive sleep apnoea syndrome in Chinese children: a two-phase community study.
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  Data: <searchLink fieldCode="JN" term="%22Thorax%22">Thorax</searchLink>. Nov2010, Vol. 65 Issue 11, p991-997. 7p.
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  Data: *<searchLink fieldCode="DE" term="%22SLEEP+apnea+syndromes%22">SLEEP apnea syndromes</searchLink><br />*<searchLink fieldCode="DE" term="%22CHILDREN'S+health%22">CHILDREN'S health</searchLink><br />*<searchLink fieldCode="DE" term="%22DISEASE+prevalence%22">DISEASE prevalence</searchLink><br />*<searchLink fieldCode="DE" term="%22SLEEP+disorders+in+children%22">SLEEP disorders in children</searchLink><br />*<searchLink fieldCode="DE" term="%22POLYSOMNOGRAPHY%22">POLYSOMNOGRAPHY</searchLink><br />*<searchLink fieldCode="DE" term="%22CHINESE+people%22">CHINESE people</searchLink><br />*<searchLink fieldCode="DE" term="%22DISEASE+risk+factors%22">DISEASE risk factors</searchLink>
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  Data: OBJECTIVE: To determine the prevalence and risk factors of obstructive sleep apnoea syndrome (OSAS) in Chinese children using a two-phase community-based study design. METHODS: Children from 13 primary schools were randomly recruited. A validated OSAS screening questionnaire was completed by their parents. Children at high risk of OSAS and a randomly chosen low-risk group were invited to undergo overnight polysomnographic study and clinical examination. The the sex-specific prevalence rate was measured using different cutoffs (obstructive apnoea hypopnoea index ≥1, ≥1.5, ≥3 and ≥5 and obstructive apnoea index ≥5) and risk factors associated with OSAS were evaluated with logistic regression. RESULTS: 6447 completed questionnaires were returned (out of 9172 questionnaires; 70.3%). 586 children (9.1%; 405 boys and 181 girls) children belonged to the high-risk group. A total of 619 (410 and 209 from the high and low-risk group, respectively) subjects underwent overnight polysomnagraphy. Depending on the cutoffs, the prevalence rate of childhood OSAS varied from 4.8% to 40.3%. Using the International Criteria of Sleep Disorders version II, the OSAS prevalence for boys and girls was 5.8% and 3.8%, respectively. Male gender, body mass index z-score and increased adenoid and tonsil size were independently associated with OSAS. CONCLUSIONS: The prevalence rate of OSAS in children was contingent on the cutoff used. The inclusion of symptoms as a part of the diagnostic criteria greatly reduced the prevalence. A further prospective and outcome study is needed to define a clinically significant diagnostic cutoff for childhood OSAS. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of Thorax is the property of BMJ Publishing Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Code: eng
        Text: English
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        PageCount: 7
        StartPage: 991
    Subjects:
      – SubjectFull: SLEEP apnea syndromes
        Type: general
      – SubjectFull: CHILDREN'S health
        Type: general
      – SubjectFull: DISEASE prevalence
        Type: general
      – SubjectFull: SLEEP disorders in children
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      – SubjectFull: POLYSOMNOGRAPHY
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      – SubjectFull: CHINESE people
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      – SubjectFull: DISEASE risk factors
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      – TitleFull: Epidemiology of obstructive sleep apnoea syndrome in Chinese children: a two-phase community study.
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              Text: Nov2010
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              Y: 2010
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