Analysis of the effects of eating and emotions on reproductive axis function in patients with functional hypothalamic amenorrhea.

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Title: Analysis of the effects of eating and emotions on reproductive axis function in patients with functional hypothalamic amenorrhea.
Authors: Lu, Ye1 (AUTHOR), Chen, Yao2 (AUTHOR), Zhao, Yuting1 (AUTHOR), Wang, Yulu1 (AUTHOR), Chen, Hang1 (AUTHOR), Zhang, Feifei1 (AUTHOR), Li, Xin1 (AUTHOR) lxsure@fudan.edu.cn
Source: Journal of Psychosomatic Obstetrics & Gynecology. Dec2024, Vol. 45 Issue 1, p1-7. 7p.
Subject Terms: *EATING disorders, *AFFECTIVE disorders, *ODDS ratio, *BULIMIA, *AMENORRHEA
Abstract: Objective: To investigate the effects of eating and emotions on reproductive axis function in patients with functional hypothalamic amenorrhea (FHA). Methods: A retrospective cohort study was conducted to summarize the clinical and endocrine characteristics of 58 patients with FHA at initial diagnosis and to follow up the recovery of ovulation and spontaneous menstruation in the patients to investigate these biochemical indicators and their effects on recovery outcomes. Results: Among patients with FHA, 13.8% (8/58) and 15.5% (9/58) had above moderately severe depressive and severe anxiety symptoms respectively, and 25.9% (15/58) were at high risk for eating disorders. 34.5% (20/58) were included assessed as having recovered. The non-recovered group had higher scores on the Patient Health Questionnaire (PHQ-9) (p =.022) and higher scores on the Eating Attitude Test-26 (EAT-26) (p =.03) as well as bulimia and food preoccupation (p =.041). Follicle diameter >5 mm at initial diagnosis was an independent factor influencing recovery of reproductive axis function (odds ratio = 7.532; 95% confidence interval, 1.321–42.930; p =.023). Conculsions: Mood disorders and a certain risk of eating disorders were present in FHA. These, together with weight loss, endocrine and follicle size, could influence the outcome. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Psychosomatic Obstetrics & Gynecology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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Items – Name: Title
  Label: Title
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  Data: Analysis of the effects of eating and emotions on reproductive axis function in patients with functional hypothalamic amenorrhea.
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  Data: <searchLink fieldCode="AR" term="%22Lu%2C+Ye%22">Lu, Ye</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chen%2C+Yao%22">Chen, Yao</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhao%2C+Yuting%22">Zhao, Yuting</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Yulu%22">Wang, Yulu</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chen%2C+Hang%22">Chen, Hang</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhang%2C+Feifei%22">Zhang, Feifei</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Li%2C+Xin%22">Li, Xin</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> lxsure@fudan.edu.cn</i>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Psychosomatic+Obstetrics+%26+Gynecology%22">Journal of Psychosomatic Obstetrics & Gynecology</searchLink>. Dec2024, Vol. 45 Issue 1, p1-7. 7p.
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  Data: *<searchLink fieldCode="DE" term="%22EATING+disorders%22">EATING disorders</searchLink><br />*<searchLink fieldCode="DE" term="%22AFFECTIVE+disorders%22">AFFECTIVE disorders</searchLink><br />*<searchLink fieldCode="DE" term="%22ODDS+ratio%22">ODDS ratio</searchLink><br />*<searchLink fieldCode="DE" term="%22BULIMIA%22">BULIMIA</searchLink><br />*<searchLink fieldCode="DE" term="%22AMENORRHEA%22">AMENORRHEA</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objective: To investigate the effects of eating and emotions on reproductive axis function in patients with functional hypothalamic amenorrhea (FHA). Methods: A retrospective cohort study was conducted to summarize the clinical and endocrine characteristics of 58 patients with FHA at initial diagnosis and to follow up the recovery of ovulation and spontaneous menstruation in the patients to investigate these biochemical indicators and their effects on recovery outcomes. Results: Among patients with FHA, 13.8% (8/58) and 15.5% (9/58) had above moderately severe depressive and severe anxiety symptoms respectively, and 25.9% (15/58) were at high risk for eating disorders. 34.5% (20/58) were included assessed as having recovered. The non-recovered group had higher scores on the Patient Health Questionnaire (PHQ-9) (p =.022) and higher scores on the Eating Attitude Test-26 (EAT-26) (p =.03) as well as bulimia and food preoccupation (p =.041). Follicle diameter >5 mm at initial diagnosis was an independent factor influencing recovery of reproductive axis function (odds ratio = 7.532; 95% confidence interval, 1.321–42.930; p =.023). Conculsions: Mood disorders and a certain risk of eating disorders were present in FHA. These, together with weight loss, endocrine and follicle size, could influence the outcome. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Psychosomatic Obstetrics & Gynecology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1080/0167482X.2024.2375718
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      – Code: eng
        Text: English
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        PageCount: 7
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      – SubjectFull: EATING disorders
        Type: general
      – SubjectFull: AFFECTIVE disorders
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      – SubjectFull: ODDS ratio
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      – SubjectFull: BULIMIA
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      – SubjectFull: AMENORRHEA
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      – TitleFull: Analysis of the effects of eating and emotions on reproductive axis function in patients with functional hypothalamic amenorrhea.
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            – D: 01
              M: 12
              Text: Dec2024
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              Y: 2024
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