Platelet-Rich Plasma: Characteristics and Current Review of its Use in Surgery.
Title: | Platelet-Rich Plasma: Characteristics and Current Review of its Use in Surgery. |
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Authors: | Odlozilova, Sarka1,2 (AUTHOR), Paral, Jiri1,2,3 (AUTHOR), Sirovy, Miroslav1,2 (AUTHOR), Zajak, Jank1,2 (AUTHOR), Fibir, Ales3,4 (AUTHOR) |
Source: | Polish Journal of Surgery. 2024, Vol. 96 Issue 5, p59-66. 8p. |
Subject Terms: | *SURGERY, *PLATELET-rich plasma, *BIOLOGICAL products, *SURGICAL indications, *WOUND healing |
Abstract: | Platelet-rich plasma (PRP) is presently employed across various medical disciplines, including surgical specialties. It is primarily used in the healing of chronic wounds, burn medicine, tissue regeneration support, and scar correction as well as in other surgical and orthopedic indications. Wounds, in general, possess a pro-inflammatory biochemical environment characterized by high protease activity that diminishes the effective concentration of growth factors. In contrast, PRP serves as a source of growth factors and exhibits mitogenic, angiogenic, and chemotactic properties. PRP is a biological product defined as a portion of the autologous blood's plasma fraction with a higher than physiological platelet concentration. PRP is obtained through the centrifugation of blood samples collected from patients. The insights into the biology, mechanism of action, and classification of PRP presented in this review can assist medical professionals in orienting themselves and comprehending the possibilities of the clinical application of this therapy, which remains a subject of investigation and validation. This review summarizes up-to-date information regarding the use of PRP, primarily in burn and reconstructive surgery, plastic surgery, traumatology, and general surgery. [ABSTRACT FROM AUTHOR] |
Copyright of Polish Journal of Surgery is the property of Fundacja Polski Przedglad Chirurgiczny and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
Database: | Academic Search Complete |
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Items | – Name: Title Label: Title Group: Ti Data: Platelet-Rich Plasma: Characteristics and Current Review of its Use in Surgery. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Odlozilova%2C+Sarka%22">Odlozilova, Sarka</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Paral%2C+Jiri%22">Paral, Jiri</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sirovy%2C+Miroslav%22">Sirovy, Miroslav</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zajak%2C+Jank%22">Zajak, Jank</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fibir%2C+Ales%22">Fibir, Ales</searchLink><relatesTo>3,4</relatesTo> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Polish+Journal+of+Surgery%22">Polish Journal of Surgery</searchLink>. 2024, Vol. 96 Issue 5, p59-66. 8p. – Name: Subject Label: Subject Terms Group: Su Data: *<searchLink fieldCode="DE" term="%22SURGERY%22">SURGERY</searchLink><br />*<searchLink fieldCode="DE" term="%22PLATELET-rich+plasma%22">PLATELET-rich plasma</searchLink><br />*<searchLink fieldCode="DE" term="%22BIOLOGICAL+products%22">BIOLOGICAL products</searchLink><br />*<searchLink fieldCode="DE" term="%22SURGICAL+indications%22">SURGICAL indications</searchLink><br />*<searchLink fieldCode="DE" term="%22WOUND+healing%22">WOUND healing</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Platelet-rich plasma (PRP) is presently employed across various medical disciplines, including surgical specialties. It is primarily used in the healing of chronic wounds, burn medicine, tissue regeneration support, and scar correction as well as in other surgical and orthopedic indications. Wounds, in general, possess a pro-inflammatory biochemical environment characterized by high protease activity that diminishes the effective concentration of growth factors. In contrast, PRP serves as a source of growth factors and exhibits mitogenic, angiogenic, and chemotactic properties. PRP is a biological product defined as a portion of the autologous blood's plasma fraction with a higher than physiological platelet concentration. PRP is obtained through the centrifugation of blood samples collected from patients. The insights into the biology, mechanism of action, and classification of PRP presented in this review can assist medical professionals in orienting themselves and comprehending the possibilities of the clinical application of this therapy, which remains a subject of investigation and validation. This review summarizes up-to-date information regarding the use of PRP, primarily in burn and reconstructive surgery, plastic surgery, traumatology, and general surgery. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Polish Journal of Surgery is the property of Fundacja Polski Przedglad Chirurgiczny and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.5604/01.3001.0054.6750 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 59 Subjects: – SubjectFull: SURGERY Type: general – SubjectFull: PLATELET-rich plasma Type: general – SubjectFull: BIOLOGICAL products Type: general – SubjectFull: SURGICAL indications Type: general – SubjectFull: WOUND healing Type: general Titles: – TitleFull: Platelet-Rich Plasma: Characteristics and Current Review of its Use in Surgery. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Odlozilova, Sarka – PersonEntity: Name: NameFull: Paral, Jiri – PersonEntity: Name: NameFull: Sirovy, Miroslav – PersonEntity: Name: NameFull: Zajak, Jank – PersonEntity: Name: NameFull: Fibir, Ales IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: 2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 0032373X Numbering: – Type: volume Value: 96 – Type: issue Value: 5 Titles: – TitleFull: Polish Journal of Surgery Type: main |
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