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Invasive Group A Streptococcus Hypervirulent M1UK Clone, Canada, 2018-2023.

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Title: Invasive Group A Streptococcus Hypervirulent M1UK Clone, Canada, 2018-2023.
Authors: Golden, Alyssa R.1 alyssa.golden@phac-aspc.gc.ca, Griffith, Averil1, Tyrrell, Gregory J.2, Kus, Julianne V.3,4, McGeer, Allison5, Domingo, Marc-Christian6, Grant, Jennifer7, Minion, Jessica8, Van Caeseele, Paul9, Desnoyers, Guillaume10, Haldane, David11, Yang Yu12, Xiaofeng Ding13, Steven, Laura14, McFadzen, Jan15, Primeau, Courtney16, Martin, Irene1
Source: Emerging Infectious Diseases. Nov2024, Vol. 30 Issue 11, p2409-2413. 5p.
Subject Terms: *STREPTOCOCCUS, *GENOMICS, *GENE clusters, *BACTERIOPHAGES
Geographic Terms: CANADA
Abstract: To determine invasive group A Streptococcus trends in Canada, we characterized emm1 isolates collected during 2018-2023. The percentage of hypervirulent M1UK lineage isolates increased significantly, from 22.1% in 2018 to 60.2% in 2023. Genomic analysis identified geographically and temporally associated clusters and genes associated with virulent bacteriophage acquisition. [ABSTRACT FROM AUTHOR]
Copyright of Emerging Infectious Diseases is the property of Centers for Disease Control & Prevention (CDC) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Invasive Group A Streptococcus Hypervirulent M1<subscript>UK</subscript> Clone, Canada, 2018-2023.
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  Data: To determine invasive group A Streptococcus trends in Canada, we characterized emm1 isolates collected during 2018-2023. The percentage of hypervirulent M1UK lineage isolates increased significantly, from 22.1% in 2018 to 60.2% in 2023. Genomic analysis identified geographically and temporally associated clusters and genes associated with virulent bacteriophage acquisition. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Emerging Infectious Diseases is the property of Centers for Disease Control & Prevention (CDC) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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