Bibliographic Details
| Title: |
Development and validation of a new scoring system to discriminate between uncomplicated and complicated appendicitis. |
| Authors: |
Mori, Mikito1 (AUTHOR) mikimori45@yahoo.co.jp, Shuto, Kiyohiko1 (AUTHOR), Kosugi, Chihiro1 (AUTHOR), Narushima, Kazuo2 (AUTHOR), Hirano, Atsushi3 (AUTHOR), Usui, Akihiro1 (AUTHOR), Nojima, Hiroyuki1 (AUTHOR), Hirota, Mihono1 (AUTHOR), Sazuka, Tetsutaro1 (AUTHOR), Yamazaki, Masato1 (AUTHOR), Fujino, Takashi4 (AUTHOR), Yamazaki, Kazuto4 (AUTHOR), Shimizu, Hiroaki1 (AUTHOR), Koda, Keiji1 (AUTHOR) |
| Source: |
Scientific Reports. 8/27/2024, Vol. 14 Issue 1, p1-8. 8p. |
| Abstract: |
A scoring system to discriminate between uncomplicated and complicated appendicitis is beneficial to determine the optimal treatment for acute appendicitis. We developed a scoring system to discriminate between uncomplicated and complicated appendicitis and assessed the clinical usefulness of the scoring system using external validation. A total of 299 patients with acute appendicitis were retrospectively reviewed. One hundred and ninety-nine patients were assigned to the model development group, while the other 100 patients were assigned to an external validation group. A scoring system for complicated appendicitis was created using a final multivariate logistic regression model with six independent predictors. The area under the receiver operating characteristic curve of the scoring system was 0.882 (95% confidence interval: 0.835–0.929). The cutoff point of the scoring system was 12, and the sensitivity and specificity were 82.9% and 86.2%, respectively. In the external validation group, the area under the receiver operating characteristic curve of the scoring system was 0.868 (95% confidence interval 0.794–0.942), and there was no significant difference between the groups in the area under the receiver operating characteristic curve (P = 0.750). Our newly developed scoring system may contribute to prompt determination of the optimal treatment for acute appendicitis. [ABSTRACT FROM AUTHOR] |
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