Academic Journal
View in EDS
HTML Full Text

Comparison of two apheresis systems for granulocyte collection without hydroxyethyl starch.

Bibliographic Details
Title: Comparison of two apheresis systems for granulocyte collection without hydroxyethyl starch.
Authors: Hosoi, Hiroki1,2 (AUTHOR) h-hosoi@wakayama-med.ac.jp, Nakajima, Shiho2 (AUTHOR), Tsujimoto, Hiroshi3 (AUTHOR), Murata, Shogo1 (AUTHOR), Hori, Yoshikazu1 (AUTHOR), Kuriyama, Kodai1,4 (AUTHOR), Mushino, Toshiki1 (AUTHOR), Matsunami, Misako2 (AUTHOR), Nishikawa, Akinori1,2 (AUTHOR), Kounami, Shinji3 (AUTHOR), Hanaoka, Nobuyoshi1,5 (AUTHOR), Sonoki, Takashi1,2 (AUTHOR)
Source: Vox Sanguinis. Jan2024, Vol. 119 Issue 1, p62-69. 8p.
Subject Terms: *HYDROXYETHYL starch, *ERYTHROCYTES, *LEUKAPHERESIS, *BLOOD sedimentation, *HEMODILUTION, *COLLECTIONS
Abstract: Background and Objectives: Granulocyte transfusion (GTX) is a treatment option for severe infections in patients with neutropenia. In previous studies, hydroxyethyl starch (HES) was used to enhance red blood cell sedimentation for granulocyte collection (GC). However, there are safety concerns about HES, and HES is not readily available in some countries. Therefore, we compared the granulocyte counts and GC efficiency achieved by two apheresis systems without HES. Materials and Methods: All consecutive GC procedures performed between July 2011 and March 2018 at our hospital were analysed. COBE Spectra was used until 5 February 2016, and Spectra Optia was used afterwards. HES was not used. Results: Twenty‐six GC procedures were performed, including 18 performed using COBE Spectra and 8 using Spectra Optia. When Spectra Optia was used, >1 × 1010 neutrophils were collected from seven of the eight (88%) procedures. Although there was no significant difference in the granulocyte yield between COBE Spectra‐based and Spectra Optia‐based GC procedures, the collection efficiency of Spectra Optia was significantly higher than that of COBE Spectra (p = 0.021). Furthermore, the granulocyte yields of Spectra Optia‐based GC tended to be more strongly correlated with the peripheral blood neutrophil count on the day of apheresis than those of COBE Spectra‐based GC. Conclusion: Our results suggest that Spectra Optia achieves greater GC efficiency than COBE Spectra, even without HES. GTX may be a therapeutic option for severe neutropenia, even in places where HES is not available. [ABSTRACT FROM AUTHOR]
Copyright of Vox Sanguinis is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Academic Search Complete
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
CustomLinks:
  – Url: https://resolver.ebsco.com/c/xy5jbn/result?sid=EBSCO:a9h&genre=article&issn=00429007&ISBN=&volume=119&issue=1&date=20240101&spage=62&pages=62-69&title=Vox Sanguinis&atitle=Comparison%20of%20two%20apheresis%20systems%20for%20granulocyte%20collection%20without%20hydroxyethyl%20starch.&aulast=Hosoi%2C%20Hiroki&id=DOI:10.1111/vox.13558
    Name: Full Text Finder (for New FTF UI) (s8985755)
    Category: fullText
    Text: Find It @ SCU Libraries
    MouseOverText: Find It @ SCU Libraries
Header DbId: a9h
DbLabel: Academic Search Complete
An: 174762386
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Comparison of two apheresis systems for granulocyte collection without hydroxyethyl starch.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Hosoi%2C+Hiroki%22">Hosoi, Hiroki</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> h-hosoi@wakayama-med.ac.jp</i><br /><searchLink fieldCode="AR" term="%22Nakajima%2C+Shiho%22">Nakajima, Shiho</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tsujimoto%2C+Hiroshi%22">Tsujimoto, Hiroshi</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Murata%2C+Shogo%22">Murata, Shogo</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hori%2C+Yoshikazu%22">Hori, Yoshikazu</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kuriyama%2C+Kodai%22">Kuriyama, Kodai</searchLink><relatesTo>1,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mushino%2C+Toshiki%22">Mushino, Toshiki</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Matsunami%2C+Misako%22">Matsunami, Misako</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nishikawa%2C+Akinori%22">Nishikawa, Akinori</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kounami%2C+Shinji%22">Kounami, Shinji</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hanaoka%2C+Nobuyoshi%22">Hanaoka, Nobuyoshi</searchLink><relatesTo>1,5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sonoki%2C+Takashi%22">Sonoki, Takashi</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Vox+Sanguinis%22">Vox Sanguinis</searchLink>. Jan2024, Vol. 119 Issue 1, p62-69. 8p.
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: *<searchLink fieldCode="DE" term="%22HYDROXYETHYL+starch%22">HYDROXYETHYL starch</searchLink><br />*<searchLink fieldCode="DE" term="%22ERYTHROCYTES%22">ERYTHROCYTES</searchLink><br />*<searchLink fieldCode="DE" term="%22LEUKAPHERESIS%22">LEUKAPHERESIS</searchLink><br />*<searchLink fieldCode="DE" term="%22BLOOD+sedimentation%22">BLOOD sedimentation</searchLink><br />*<searchLink fieldCode="DE" term="%22HEMODILUTION%22">HEMODILUTION</searchLink><br />*<searchLink fieldCode="DE" term="%22COLLECTIONS%22">COLLECTIONS</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background and Objectives: Granulocyte transfusion (GTX) is a treatment option for severe infections in patients with neutropenia. In previous studies, hydroxyethyl starch (HES) was used to enhance red blood cell sedimentation for granulocyte collection (GC). However, there are safety concerns about HES, and HES is not readily available in some countries. Therefore, we compared the granulocyte counts and GC efficiency achieved by two apheresis systems without HES. Materials and Methods: All consecutive GC procedures performed between July 2011 and March 2018 at our hospital were analysed. COBE Spectra was used until 5 February 2016, and Spectra Optia was used afterwards. HES was not used. Results: Twenty‐six GC procedures were performed, including 18 performed using COBE Spectra and 8 using Spectra Optia. When Spectra Optia was used, >1 × 1010 neutrophils were collected from seven of the eight (88%) procedures. Although there was no significant difference in the granulocyte yield between COBE Spectra‐based and Spectra Optia‐based GC procedures, the collection efficiency of Spectra Optia was significantly higher than that of COBE Spectra (p = 0.021). Furthermore, the granulocyte yields of Spectra Optia‐based GC tended to be more strongly correlated with the peripheral blood neutrophil count on the day of apheresis than those of COBE Spectra‐based GC. Conclusion: Our results suggest that Spectra Optia achieves greater GC efficiency than COBE Spectra, even without HES. GTX may be a therapeutic option for severe neutropenia, even in places where HES is not available. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Vox Sanguinis is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://login.libproxy.scu.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=a9h&AN=174762386
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/vox.13558
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 62
    Subjects:
      – SubjectFull: HYDROXYETHYL starch
        Type: general
      – SubjectFull: ERYTHROCYTES
        Type: general
      – SubjectFull: LEUKAPHERESIS
        Type: general
      – SubjectFull: BLOOD sedimentation
        Type: general
      – SubjectFull: HEMODILUTION
        Type: general
      – SubjectFull: COLLECTIONS
        Type: general
    Titles:
      – TitleFull: Comparison of two apheresis systems for granulocyte collection without hydroxyethyl starch.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Hosoi, Hiroki
      – PersonEntity:
          Name:
            NameFull: Nakajima, Shiho
      – PersonEntity:
          Name:
            NameFull: Tsujimoto, Hiroshi
      – PersonEntity:
          Name:
            NameFull: Murata, Shogo
      – PersonEntity:
          Name:
            NameFull: Hori, Yoshikazu
      – PersonEntity:
          Name:
            NameFull: Kuriyama, Kodai
      – PersonEntity:
          Name:
            NameFull: Mushino, Toshiki
      – PersonEntity:
          Name:
            NameFull: Matsunami, Misako
      – PersonEntity:
          Name:
            NameFull: Nishikawa, Akinori
      – PersonEntity:
          Name:
            NameFull: Kounami, Shinji
      – PersonEntity:
          Name:
            NameFull: Hanaoka, Nobuyoshi
      – PersonEntity:
          Name:
            NameFull: Sonoki, Takashi
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Text: Jan2024
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-print
              Value: 00429007
          Numbering:
            – Type: volume
              Value: 119
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Vox Sanguinis
              Type: main
ResultId 1