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Advances in Molecular Medicine: Unravelling Disease Complexity and Pioneering Precision Healthcare.

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Title: Advances in Molecular Medicine: Unravelling Disease Complexity and Pioneering Precision Healthcare.
Authors: Bustin, Stephen A.1 (AUTHOR) stephen.bustin@aru.ac.uk, Jellinger, Kurt A.2 (AUTHOR) stephen.bustin@aru.ac.uk
Source: International Journal of Molecular Sciences. Sep2023, Vol. 24 Issue 18, p14168. 8p.
Subject Terms: *MOLECULAR pathology, *MEDICAL care, *MEDICAL personnel, *DRUGS, *THERAPEUTICS, *PRECISION farming, *TRANSCRANIAL direct current stimulation
Abstract: On the other hand, trials evaluating systemic therapies have predominantly involved patients with extra-hepatic disease, leading to systemic therapy being the primary strategy for this population. Molecular pathology focuses on the study and interpretation of molecular and genetic changes in tissues and cells to aid in the diagnosis, pathogenesis, prognosis, and treatment of diseases. Most locoregional HCC trials have been conducted in patients without extra-hepatic disease, making locoregional therapies a primary choice for those with limited disease burden. By tailoring treatments to individual patients based on their unique molecular profile, molecular therapeutics maximise treatment efficacy while minimising the risk of treatment resistance and side effects. [Extracted from the article]
Copyright of International Journal of Molecular Sciences is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Advances in Molecular Medicine: Unravelling Disease Complexity and Pioneering Precision Healthcare.
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  Data: <searchLink fieldCode="AR" term="%22Bustin%2C+Stephen+A%2E%22">Bustin, Stephen A.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> stephen.bustin@aru.ac.uk</i><br /><searchLink fieldCode="AR" term="%22Jellinger%2C+Kurt+A%2E%22">Jellinger, Kurt A.</searchLink><relatesTo>2</relatesTo> (AUTHOR)<i> stephen.bustin@aru.ac.uk</i>
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  Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Molecular+Sciences%22">International Journal of Molecular Sciences</searchLink>. Sep2023, Vol. 24 Issue 18, p14168. 8p.
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  Data: *<searchLink fieldCode="DE" term="%22MOLECULAR+pathology%22">MOLECULAR pathology</searchLink><br />*<searchLink fieldCode="DE" term="%22MEDICAL+care%22">MEDICAL care</searchLink><br />*<searchLink fieldCode="DE" term="%22MEDICAL+personnel%22">MEDICAL personnel</searchLink><br />*<searchLink fieldCode="DE" term="%22DRUGS%22">DRUGS</searchLink><br />*<searchLink fieldCode="DE" term="%22THERAPEUTICS%22">THERAPEUTICS</searchLink><br />*<searchLink fieldCode="DE" term="%22PRECISION+farming%22">PRECISION farming</searchLink><br />*<searchLink fieldCode="DE" term="%22TRANSCRANIAL+direct+current+stimulation%22">TRANSCRANIAL direct current stimulation</searchLink>
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  Data: On the other hand, trials evaluating systemic therapies have predominantly involved patients with extra-hepatic disease, leading to systemic therapy being the primary strategy for this population. Molecular pathology focuses on the study and interpretation of molecular and genetic changes in tissues and cells to aid in the diagnosis, pathogenesis, prognosis, and treatment of diseases. Most locoregional HCC trials have been conducted in patients without extra-hepatic disease, making locoregional therapies a primary choice for those with limited disease burden. By tailoring treatments to individual patients based on their unique molecular profile, molecular therapeutics maximise treatment efficacy while minimising the risk of treatment resistance and side effects. [Extracted from the article]
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  Data: <i>Copyright of International Journal of Molecular Sciences is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.3390/ijms241814168
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        Text: English
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        StartPage: 14168
    Subjects:
      – SubjectFull: MOLECULAR pathology
        Type: general
      – SubjectFull: MEDICAL care
        Type: general
      – SubjectFull: MEDICAL personnel
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      – SubjectFull: DRUGS
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      – SubjectFull: THERAPEUTICS
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      – SubjectFull: PRECISION farming
        Type: general
      – SubjectFull: TRANSCRANIAL direct current stimulation
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              M: 09
              Text: Sep2023
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              Y: 2023
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