The activity of candlenut oil in the nanostructured lipid carrier system on hair growth in rats.
| Title: | The activity of candlenut oil in the nanostructured lipid carrier system on hair growth in rats. |
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| Authors: | Erawati, Tristiana Munandar1, Rosita, Noorma1 noorma-r@ff.unair.ac.id, Rachmania, Intan1 |
| Source: | Journal of Public Health in Africa. Suppliment2023, Vol. 14, p1-5. 5p. |
| Subject Terms: | *HAIR growth, *PETROLEUM, *LIPIDS, *RATS, *CACAO |
| Abstract: | Background: Candlenut oil (Aleurites moluccana L. Willd), which is also called Aleurites moluccana Seed (AMS) oil, is empirically effective as a hair growth agent, it is an unstable substance. Nanostructured Lipid Carrier (NLC) is a delivery system that is proven to increase the effectiveness and stability of the material, and the usage of solid lipid combination: beeswax-oleum cacao can produce good NLC characteristics. Objective: To determine the effectiveness of NLC_AMS oil with different combination of beeswax-oleum cacao (100:0; 50:50; 25:75; and 0:100) as a hair growth agent, using rats as subjects. Methods: NLC-AMS oil was made using 20% of total lipid with 5% AMS oil as liquid lipid and 15% solid lipid; combinations of beeswax-oleum cacao were of different ratios (100:0; 50:50; 25:75; and 0:100). NLC was made by High Shear Homogenization (HPH) method. Hair growth activity test carried out on male white rats using the research methods of Yoon (2010). Results: The addition of oleum cacao as a solid lipid did not affect the pH, but increased the consistency and decreased the particle size of NLC-AMS oil. There was a relationship between the characteristic of NLC and the hair growth activity test: the small particle size and low viscosity had greater hair growth activity. Conclusion: The usage of solid lipid combination: beeswaxoleum cacao can produce better NLC characteristics and had higher hair growth activity than the formulas that used single lipid. [ABSTRACT FROM AUTHOR] |
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| Items | – Name: Title Label: Title Group: Ti Data: The activity of candlenut oil in the nanostructured lipid carrier system on hair growth in rats. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Erawati%2C+Tristiana+Munandar%22">Erawati, Tristiana Munandar</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Rosita%2C+Noorma%22">Rosita, Noorma</searchLink><relatesTo>1</relatesTo><i> noorma-r@ff.unair.ac.id</i><br /><searchLink fieldCode="AR" term="%22Rachmania%2C+Intan%22">Rachmania, Intan</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Public+Health+in+Africa%22">Journal of Public Health in Africa</searchLink>. Suppliment2023, Vol. 14, p1-5. 5p. – Name: Subject Label: Subject Terms Group: Su Data: *<searchLink fieldCode="DE" term="%22HAIR+growth%22">HAIR growth</searchLink><br />*<searchLink fieldCode="DE" term="%22PETROLEUM%22">PETROLEUM</searchLink><br />*<searchLink fieldCode="DE" term="%22LIPIDS%22">LIPIDS</searchLink><br />*<searchLink fieldCode="DE" term="%22RATS%22">RATS</searchLink><br />*<searchLink fieldCode="DE" term="%22CACAO%22">CACAO</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Background: Candlenut oil (Aleurites moluccana L. Willd), which is also called Aleurites moluccana Seed (AMS) oil, is empirically effective as a hair growth agent, it is an unstable substance. Nanostructured Lipid Carrier (NLC) is a delivery system that is proven to increase the effectiveness and stability of the material, and the usage of solid lipid combination: beeswax-oleum cacao can produce good NLC characteristics. Objective: To determine the effectiveness of NLC_AMS oil with different combination of beeswax-oleum cacao (100:0; 50:50; 25:75; and 0:100) as a hair growth agent, using rats as subjects. Methods: NLC-AMS oil was made using 20% of total lipid with 5% AMS oil as liquid lipid and 15% solid lipid; combinations of beeswax-oleum cacao were of different ratios (100:0; 50:50; 25:75; and 0:100). NLC was made by High Shear Homogenization (HPH) method. Hair growth activity test carried out on male white rats using the research methods of Yoon (2010). Results: The addition of oleum cacao as a solid lipid did not affect the pH, but increased the consistency and decreased the particle size of NLC-AMS oil. There was a relationship between the characteristic of NLC and the hair growth activity test: the small particle size and low viscosity had greater hair growth activity. Conclusion: The usage of solid lipid combination: beeswaxoleum cacao can produce better NLC characteristics and had higher hair growth activity than the formulas that used single lipid. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Public Health in Africa is the property of PAGEPress and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.4081/jphia.2023.2519 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 1 Subjects: – SubjectFull: HAIR growth Type: general – SubjectFull: PETROLEUM Type: general – SubjectFull: LIPIDS Type: general – SubjectFull: RATS Type: general – SubjectFull: CACAO Type: general Titles: – TitleFull: The activity of candlenut oil in the nanostructured lipid carrier system on hair growth in rats. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Erawati, Tristiana Munandar – PersonEntity: Name: NameFull: Rosita, Noorma – PersonEntity: Name: NameFull: Rachmania, Intan IsPartOfRelationships: – BibEntity: Dates: – D: 02 M: 01 Text: Suppliment2023 Type: published Y: 2023 Identifiers: – Type: issn-print Value: 20389922 Numbering: – Type: volume Value: 14 Titles: – TitleFull: Journal of Public Health in Africa Type: main |
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