Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions.
| Title: | Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions. |
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| Authors: | Machaea, Sello1 (AUTHOR), Chitnis, Milind1 (AUTHOR), Nongena, Phumza2 (AUTHOR) |
| Source: | African Journal of Paediatric Surgery. Jan-Mar2023, Vol. 20 Issue 1, p46-50. 5p. 1 Diagram, 2 Charts, 2 Graphs. |
| Subject Terms: | *NEONATAL mortality, *GASTROSCHISIS, *MIDDLE-income countries, *LOW-income countries, *NEONATAL intensive care |
| Geographic Terms: | EASTERN Cape (South Africa), SOUTH Africa |
| Abstract: | Context: Gastroschisis is a common abdominal wall defect faced by paediatric surgeons worldwide. Early gastroschisis detection, access to improved neonatal intensive care, parenteral nutrition and surgical techniques have led to a reported improvement in mortality of between 4% and 8% in high-income countries. In low to middle income countries, such as in Southern Africa, however, there is as much as 84% mortality among patients with gastroschisis. This is thought to be due to factors such as lack of antenatal screening, access to neonatal intensive care services and parenteral nutrition. Aims: The purpose of this study was to calculate the prevalence of gastroschisis and report on its neonatal mortality in the Eastern Cape Province of South Africa. Settings and Design: A retrospective observational study on all neonates with gastroschisis, presenting to a tertiary facility offering paediatric surgical services within the Eastern Cape Province from 1 January 2016 to 31 December 2018. Subjects and Methods: A convenience sampling method was used in retrieving patient files for the study period. Statistical analysis used: Stata version 13. Results: Thirty-seven neonates were included in the study. The prevalence of gastroschisis ranged from 0.07% to 0.18% throughout the 3-year study. The majority (81%) of the neonates were outborn and delivered by mode of caesarean section. Nearly 60% (n = 22) were female. 54% (n = 20) of neonates died within the neonatal period. Conclusions: The majority of the neonates in this study were outborn and female. Although their mortality rate was higher than reported in high-income countries, it was much improved from what is reported in the low to middle income countries. [ABSTRACT FROM AUTHOR] |
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| Items | – Name: Title Label: Title Group: Ti Data: Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Machaea%2C+Sello%22">Machaea, Sello</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chitnis%2C+Milind%22">Chitnis, Milind</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nongena%2C+Phumza%22">Nongena, Phumza</searchLink><relatesTo>2</relatesTo> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22African+Journal+of+Paediatric+Surgery%22">African Journal of Paediatric Surgery</searchLink>. Jan-Mar2023, Vol. 20 Issue 1, p46-50. 5p. 1 Diagram, 2 Charts, 2 Graphs. – Name: Subject Label: Subject Terms Group: Su Data: *<searchLink fieldCode="DE" term="%22NEONATAL+mortality%22">NEONATAL mortality</searchLink><br />*<searchLink fieldCode="DE" term="%22GASTROSCHISIS%22">GASTROSCHISIS</searchLink><br />*<searchLink fieldCode="DE" term="%22MIDDLE-income+countries%22">MIDDLE-income countries</searchLink><br />*<searchLink fieldCode="DE" term="%22LOW-income+countries%22">LOW-income countries</searchLink><br />*<searchLink fieldCode="DE" term="%22NEONATAL+intensive+care%22">NEONATAL intensive care</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22EASTERN+Cape+%28South+Africa%29%22">EASTERN Cape (South Africa)</searchLink><br /><searchLink fieldCode="DE" term="%22SOUTH+Africa%22">SOUTH Africa</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Context: Gastroschisis is a common abdominal wall defect faced by paediatric surgeons worldwide. Early gastroschisis detection, access to improved neonatal intensive care, parenteral nutrition and surgical techniques have led to a reported improvement in mortality of between 4% and 8% in high-income countries. In low to middle income countries, such as in Southern Africa, however, there is as much as 84% mortality among patients with gastroschisis. This is thought to be due to factors such as lack of antenatal screening, access to neonatal intensive care services and parenteral nutrition. Aims: The purpose of this study was to calculate the prevalence of gastroschisis and report on its neonatal mortality in the Eastern Cape Province of South Africa. Settings and Design: A retrospective observational study on all neonates with gastroschisis, presenting to a tertiary facility offering paediatric surgical services within the Eastern Cape Province from 1 January 2016 to 31 December 2018. Subjects and Methods: A convenience sampling method was used in retrieving patient files for the study period. Statistical analysis used: Stata version 13. Results: Thirty-seven neonates were included in the study. The prevalence of gastroschisis ranged from 0.07% to 0.18% throughout the 3-year study. The majority (81%) of the neonates were outborn and delivered by mode of caesarean section. Nearly 60% (n = 22) were female. 54% (n = 20) of neonates died within the neonatal period. Conclusions: The majority of the neonates in this study were outborn and female. Although their mortality rate was higher than reported in high-income countries, it was much improved from what is reported in the low to middle income countries. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of African Journal of Paediatric Surgery is the property of Wolters Kluwer India Pvt Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.4103/ajps.ajps_178_21 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 46 Subjects: – SubjectFull: EASTERN Cape (South Africa) Type: general – SubjectFull: SOUTH Africa Type: general – SubjectFull: NEONATAL mortality Type: general – SubjectFull: GASTROSCHISIS Type: general – SubjectFull: MIDDLE-income countries Type: general – SubjectFull: LOW-income countries Type: general – SubjectFull: NEONATAL intensive care Type: general Titles: – TitleFull: Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Machaea, Sello – PersonEntity: Name: NameFull: Chitnis, Milind – PersonEntity: Name: NameFull: Nongena, Phumza IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan-Mar2023 Type: published Y: 2023 Identifiers: – Type: issn-print Value: 01896725 Numbering: – Type: volume Value: 20 – Type: issue Value: 1 Titles: – TitleFull: African Journal of Paediatric Surgery Type: main |
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