Academic Journal
View in EDS
HTML Full Text

Prediction of complex gastroschisis: The evolution of therapeutic techniques and their relation with fetal sonographic features.

Bibliographic Details
Title: Prediction of complex gastroschisis: The evolution of therapeutic techniques and their relation with fetal sonographic features.
Authors: Mazzoni, Giorgia1 (AUTHOR) giorgiamazzoni89@gmail.com, Alberti, Daniele2 (AUTHOR), Torri, Fabio2 (AUTHOR), Motta, Mario3 (AUTHOR), Platto, Chiara1 (AUTHOR), Franceschetti, Laura1 (AUTHOR), Sartori, Enrico1 (AUTHOR), Signorelli, Marino1 (AUTHOR)
Source: Journal of Neonatal - Perinatal Medicine. 2022, Vol. 15 Issue 1, p137-145. 9p.
Subject Terms: *SHORT bowel syndrome, *GASTROSCHISIS, *FETAL growth retardation, *NEONATAL sepsis, *ENTERAL feeding, *PARENTERAL feeding
Abstract: BACKGROUND: To analyze prenatal ultrasound (US) markers to predict treatment and adverse neonatal outcome in fetal gastroschisis. METHODS: It was conducted a retrospective single-center study considering all pregnancies with isolated gastroschisis that were treated in our department between 2008 and 2020. 17 US markers were analyzed. Moreover, the association between prenatal ultrasound signs and neonatal outcomes was analyzed: need of bowel resection, techniques of reduction, type of closure, adverse neonatal outcomes, time to full enteral feeding, length of total parenteral nutrition and length of hospitalization. RESULTS: The analysis included 21 cases. We found significant associations between intestinal dilation (≥10 mm) appeared before 30 weeks of gestation and the need of bowel resection (p = 0.001), the length of total parenteral nutrition (p = 0,0013) and the length of hospitalization (p = 0,0017). Intrauterine growth restriction (IUGR) is a risk factor for serial reduction (p = 0,035). There were no signs significantly associated with the type of closure. Hyperbilirubinemia is related with gestational age (GA) at the diagnosis of intra-abdominal bowel dilation (IABD) (p = 0.0376) and maximum IABD (p = 0.05). All newborns with sepsis had echogenic loops in uterus (p = 0.026). The relation between the GA at delivery and the GA at the extra-abdominal bowel dilation (EABD)≥10 mm was r = 0.70. CONCLUSION: We showed the significant role of the early presence of bowel dilation in predicting intestinal resection and adverse outcomes. All IUGR fetuses needed staged reduction through the silo-bag technique. The echogenic bowel was related to neonatal sepsis, while IABD was associated with hyperbilirubinemia. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Neonatal - Perinatal Medicine is the property of IOS Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Academic Search Complete
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
CustomLinks:
  – Url: https://resolver.ebsco.com/c/xy5jbn/result?sid=EBSCO:a9h&genre=article&issn=19345798&ISBN=&volume=15&issue=1&date=20220101&spage=137&pages=137-145&title=Journal of Neonatal - Perinatal Medicine&atitle=Prediction%20of%20complex%20gastroschisis%3A%20The%20evolution%20of%20therapeutic%20techniques%20and%20their%20relation%20with%20fetal%20sonographic%20features.&aulast=Mazzoni%2C%20Giorgia&id=DOI:10.3233/NPM-210746
    Name: Full Text Finder (for New FTF UI) (s8985755)
    Category: fullText
    Text: Find It @ SCU Libraries
    MouseOverText: Find It @ SCU Libraries
Header DbId: a9h
DbLabel: Academic Search Complete
An: 156138975
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Prediction of complex gastroschisis: The evolution of therapeutic techniques and their relation with fetal sonographic features.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Mazzoni%2C+Giorgia%22">Mazzoni, Giorgia</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> giorgiamazzoni89@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Alberti%2C+Daniele%22">Alberti, Daniele</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Torri%2C+Fabio%22">Torri, Fabio</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Motta%2C+Mario%22">Motta, Mario</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Platto%2C+Chiara%22">Platto, Chiara</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Franceschetti%2C+Laura%22">Franceschetti, Laura</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sartori%2C+Enrico%22">Sartori, Enrico</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Signorelli%2C+Marino%22">Signorelli, Marino</searchLink><relatesTo>1</relatesTo> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Journal+of+Neonatal+-+Perinatal+Medicine%22">Journal of Neonatal - Perinatal Medicine</searchLink>. 2022, Vol. 15 Issue 1, p137-145. 9p.
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: *<searchLink fieldCode="DE" term="%22SHORT+bowel+syndrome%22">SHORT bowel syndrome</searchLink><br />*<searchLink fieldCode="DE" term="%22GASTROSCHISIS%22">GASTROSCHISIS</searchLink><br />*<searchLink fieldCode="DE" term="%22FETAL+growth+retardation%22">FETAL growth retardation</searchLink><br />*<searchLink fieldCode="DE" term="%22NEONATAL+sepsis%22">NEONATAL sepsis</searchLink><br />*<searchLink fieldCode="DE" term="%22ENTERAL+feeding%22">ENTERAL feeding</searchLink><br />*<searchLink fieldCode="DE" term="%22PARENTERAL+feeding%22">PARENTERAL feeding</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: BACKGROUND: To analyze prenatal ultrasound (US) markers to predict treatment and adverse neonatal outcome in fetal gastroschisis. METHODS: It was conducted a retrospective single-center study considering all pregnancies with isolated gastroschisis that were treated in our department between 2008 and 2020. 17 US markers were analyzed. Moreover, the association between prenatal ultrasound signs and neonatal outcomes was analyzed: need of bowel resection, techniques of reduction, type of closure, adverse neonatal outcomes, time to full enteral feeding, length of total parenteral nutrition and length of hospitalization. RESULTS: The analysis included 21 cases. We found significant associations between intestinal dilation (≥10 mm) appeared before 30 weeks of gestation and the need of bowel resection (p = 0.001), the length of total parenteral nutrition (p = 0,0013) and the length of hospitalization (p = 0,0017). Intrauterine growth restriction (IUGR) is a risk factor for serial reduction (p = 0,035). There were no signs significantly associated with the type of closure. Hyperbilirubinemia is related with gestational age (GA) at the diagnosis of intra-abdominal bowel dilation (IABD) (p = 0.0376) and maximum IABD (p = 0.05). All newborns with sepsis had echogenic loops in uterus (p = 0.026). The relation between the GA at delivery and the GA at the extra-abdominal bowel dilation (EABD)≥10 mm was r = 0.70. CONCLUSION: We showed the significant role of the early presence of bowel dilation in predicting intestinal resection and adverse outcomes. All IUGR fetuses needed staged reduction through the silo-bag technique. The echogenic bowel was related to neonatal sepsis, while IABD was associated with hyperbilirubinemia. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Neonatal - Perinatal Medicine is the property of IOS Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://login.libproxy.scu.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=a9h&AN=156138975
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3233/NPM-210746
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 9
        StartPage: 137
    Subjects:
      – SubjectFull: SHORT bowel syndrome
        Type: general
      – SubjectFull: GASTROSCHISIS
        Type: general
      – SubjectFull: FETAL growth retardation
        Type: general
      – SubjectFull: NEONATAL sepsis
        Type: general
      – SubjectFull: ENTERAL feeding
        Type: general
      – SubjectFull: PARENTERAL feeding
        Type: general
    Titles:
      – TitleFull: Prediction of complex gastroschisis: The evolution of therapeutic techniques and their relation with fetal sonographic features.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Mazzoni, Giorgia
      – PersonEntity:
          Name:
            NameFull: Alberti, Daniele
      – PersonEntity:
          Name:
            NameFull: Torri, Fabio
      – PersonEntity:
          Name:
            NameFull: Motta, Mario
      – PersonEntity:
          Name:
            NameFull: Platto, Chiara
      – PersonEntity:
          Name:
            NameFull: Franceschetti, Laura
      – PersonEntity:
          Name:
            NameFull: Sartori, Enrico
      – PersonEntity:
          Name:
            NameFull: Signorelli, Marino
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Text: 2022
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-print
              Value: 19345798
          Numbering:
            – Type: volume
              Value: 15
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Journal of Neonatal - Perinatal Medicine
              Type: main
ResultId 1