Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline HbA1c levels (STEP-HFpEF DM): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial

Authors: Davies, Melanie J ^{a, b, †}, van der Meer, Peter ^{c, †}, Verma, Subodh ^d, Patel, Shachi ^e, Chinnakondepalli, Khaja M ^e, Borlaug, Barry A ^f, Butler, Javed ^{g, h}, Kitzman, Dalane W ⁱ, Shah, Sanjiv J ^j, Harring, Signe ^k, Salsali, Afshin ^k, Rasmussen, Søren ^k, von Lewinski, Dirk ^l, Abhayaratna, Walter ^m, Petrie, Mark C ⁿ, Kosiborod, Mikhail N ^{e, *}

Source: In The Lancet Diabetes & Endocrinology March 2025 13(3):196-209

Inflammation in Obesity-Related HFpEF: The STEP-HFpEF Program

Authors: Verma, Subodh ^{a, ∗}, Petrie, Mark C. ^{b, ∗}, Borlaug, Barry A. ^c, Butler, Javed ^{d, e}, Davies, Melanie J. ^{f, g}, Kitzman, Dalane W. ^h, Shah, Sanjiv J. ⁱ, Rönnbäck, Cecilia ^j, Abildstrøm, Steen Z. ^j, Liisberg, Karoline ^j, Wolf, Dennis ^k, von Lewinski, Dirk ^l, Lelonek, Malgorzata ^m, Melenovsky, Vojtech ⁿ, Senni, Michele ^o, Kosiborod, Mikhail N. ^{p, ∗}

Source: In Journal of the American College of Cardiology 22 October 2024 84(17):1646-1662

Semaglutide versus placebo in people with obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF DM randomised trials

Authors: Butler, Javed ^*, Shah, Sanjiv J ^*, Petrie, Mark C, Borlaug, Barry A, Abildstrøm, Steen Z, Davies, Melanie J, Hovingh, G Kees, Kitzman, Dalane W, Møller, Daniél Vega, Verma, Subodh, Einfeldt, Mette Nygaard, Lindegaard, Marie L, Rasmussen, Søren, Abhayaratna, Walter, Ahmed, Fozia Z, Ben-Gal, Tuvia, Chopra, Vijay, Ezekowitz, Justin A, Fu, Michael, Ito, Hiroshi, Lelonek, Małgorzata, Melenovský, Vojtěch, Merkely, Bela, Núñez, Julio, Perna, Eduardo, Schou, Morten, Senni, Michele, Sharma, Kavita, van der Meer, Peter, Von Lewinski, Dirk, Wolf, Dennis, Kosiborod, Mikhail N ^*

Source: In The Lancet 27 April-3 May 2024 403(10437):1635-1648

The interaction between non-coding RNAs and SGLT2: A review

Authors: Jarosz-Popek, Joanna, Eyileten, Ceren, Gager, Gloria M., Nowak, Anna, Szwed, Piotr, Wicik, Zofia, Palatini, Jeff, von Lewinski, Dirk, Sourij, Harald, Siller-Matula, Jolanta M., Postula, Marek

Source: In International Journal of Cardiology 1 March 2024 398

Effects of empagliflozin in women and men with acute myocardial infarction: An analysis from the EMMY trial

Authors: Sourij, Caren, Aziz, Faisal, Tripolt, Norbert J., Siller-Matula, Jolanta, Pferschy, Peter N., Kolesnik, Ewald, Wallner, Markus, Eyileten, Ceren, Postula, Marek, Oulhaj, Abderrahim, Sourij, Harald, von Lewinski, Dirk

Source: In Hellenic Journal of Cardiology January-February 2024 75:3-8

Automated external defibrillator delivery by drone in mountainous regions to support basic life support – A simulation study

Authors: Fischer, Philip, Rohrer, Ursula, Nürnberger, Patrick, Manninger, Martin, Scherr, Daniel, von Lewinski, Dirk, Zirlik, Andreas, Wankmüller, Christian, Kolesnik, Ewald

Source: In Resuscitation Plus June 2023 14

Association of branched-chain amino acids with mortality-the Ludwigshafen Risk and Cardiovascular Health (LURIC) study

Authors: Moissl, Angela P. ^{1, 2, 3}, Lorkowski, Stefan ^{1, 2}, Meinitzer, Andreas ⁶, Pilz, Stefan ⁸, Scharnagl, Hubert ⁶, Delgado, Graciela E. ^{3, 4}, Kleber, Marcus E. ^{2, 3, 12}, Krämer, Bernhard K. ^{3, 4, 5}, Pieske, Burkert ^{9, 10}, Grübler, Martin R. ⁸, Brussee, Helmut ⁸, von Lewinski, Dirk ¹¹, Toplak, Hermann ⁸, Fahrleitner-Pammer, Astrid ⁸, März, Winfried ^{2, 3, 6, 13, 14, 15, ∗}, Tomaschitz, Andreas ^{7, 14}

Source: In iScience 21 April 2023 26(4)

Ertugliflozin to reduce arrhythmic burden in ICD/CRT patients (ERASe-trial) – A phase III study

Authors: von Lewinski, Dirk, Tripolt, Norbert J, Sourij, Harald, Pferschy, Peter N, Oulhaj, Abderrahim, Alber, Hannes, Gwechenberger, Marianne, Martinek, Martin, Seidl, Sebastian, Moertl, Deddo, Nürnberg, Michael, Roithinger, Franz Xaver, Steinwender, Clemens, Stühlinger, Markus, Zirlik, Andreas, Benedikt, Martin, Kolesnik, Ewald, Wallner, Markus, Rohrer, Ursula, Manninger, Martin, Scherr, Daniel

Source: In American Heart Journal April 2022 246:152-160

Myofilament glycation in diabetes reduces contractility by inhibiting tropomyosin movement, is rescued by cMyBPC domains

Authors: Papadaki, Maria, Kampaengsri, Theerachat, Barrick, Samantha K., Campbell, Stuart G., von Lewinski, Dirk, Rainer, Peter P., Harris, Samantha P., Greenberg, Michael J., Kirk, Jonathan A.

Source: In Journal of Molecular and Cellular Cardiology January 2022 162:1-9

Effects of SGLT2 Inhibitors on Ion Homeostasis and Oxidative Stress associated Mechanisms in Heart Failure

Authors: Gager, Gloria M., von Lewinski, Dirk, Sourij, Harald, Jilma, Bernd, Eyileten, Ceren, Filipiak, Krzysztof, Hülsmann, Martin, Kubica, Jacek, Postula, Marek, Siller-Matula, Jolanta M.

Source: In Biomedicine & Pharmacotherapy November 2021 143

Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline HbA1clevels (STEP-HFpEF DM): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial

Authors: Davies, Melanie J, van der Meer, Peter, Verma, Subodh, Patel, Shachi, Chinnakondepalli, Khaja M, Borlaug, Barry A, Butler, Javed, Kitzman, Dalane W, Shah, Sanjiv J, Harring, Signe, Salsali, Afshin, Rasmussen, Søren, von Lewinski, Dirk, Abhayaratna, Walter, Petrie, Mark C, Kosiborod, Mikhail N

Source: The Lancet Diabetes & Endocrinology; March 2025, Vol. 13 Issue: 3 p196-209, 14p

Impact of comorbidities on mortality in hospitalized influenza patients with diabetes – Analysis of the Austrian Health Insurance

Authors: Aziz, Faisal, Aberer, Felix, Moser, Othmar, Sourij, Caren, von Lewinski, Dirk, Kaser, Susanne, Reichardt, Berthold, Sourij, Harald

Source: In Diabetes Research and Clinical Practice April 2021 174

Timing of SGLT2i initiation after acute myocardial infarction.

Authors: von Lewinski, Dirk¹ (AUTHOR) dirk.von-lewinski@medunigraz.at, Kolesnik, Ewald¹ (AUTHOR), Aziz, Faisal^2,3 (AUTHOR), Benedikt, Martin¹ (AUTHOR), Tripolt, Norbert J.^2,3 (AUTHOR), Wallner, Markus¹ (AUTHOR), Pferschy, Peter N.^2,3 (AUTHOR), von Lewinski, Friederike^2,3 (AUTHOR), Schwegel, Nora¹ (AUTHOR), Holman, Rury R.⁴ (AUTHOR), Oulhaj, Abderrahim⁵ (AUTHOR), Moertl, Deddo^6,7 (AUTHOR), Siller-Matula, Jolanta⁸ (AUTHOR), Sourij, Harald^3,9 (AUTHOR)

Source: Cardiovascular Diabetology. 9/30/2023, Vol. 22 Issue 1, p1-7. 7p.

Subject Terms: *MYOCARDIAL infarction, *CORONARY care units, *TYPE 2 diabetes, *SODIUM-glucose cotransporter 2 inhibitors

Homoarginine concentrations correlate with early depressive symptoms and the reduction in physical functioning within the first days after myocardial infarction.

Authors: Baranyi, Andreas, Meinitzer, Andreas, von Lewinski, Dirk, Wagner-Skacel, Jolana, Garcia, Sabrina Leal, Rothenhäusler, Hans-Bernd, Amouzadeh-Ghadikolai, Omid, Harpf, Leonhard, Schweinzer, Melanie, Enko, Dietmar

Source: Scientific Reports; 1/9/2025, Vol. 15 Issue 1, p1-9, 9p

Subject Terms: MYOCARDIAL infarction, PHYSICAL mobility, MENTAL depression, MEDICAL sciences, BLOOD flow

Timing of veno‐arterial extracorporeal membrane oxygenation support in patients with cardiogenic shock.

Authors: Sundermeyer, Jonas, Kellner, Caroline, Beer, Benedikt N., Dettling, Angela, Besch, Lisa, Blankenberg, Stefan, Eitel, Ingo, Frank, Derk, Frey, Norbert, Graf, Tobias, Kirchhof, Paulus, Krais, Jannis, von Lewinski, Dirk, Mangner, Norman, Möbius‐Winkler, Sven, Nordbeck, Peter, Orban, Martin, Pauschinger, Matthias, Sag, Can Martin, Scherer, Clemens

Source: European Journal of Heart Failure; Jan2025, Vol. 27 Issue 1, p40-50, 11p

Subject Terms: ARTIFICIAL blood circulation, CARDIOGENIC shock, AUTOMATIC timers, PATIENTS' attitudes, LOGISTIC regression analysis

Air Pollution and Myocardial Infarction—A New Smoker's Paradox?

Authors: von Lewinski, Friederike, Quehenberger, Franz, Sacherer, Michael, Taucher, Valentin, Strohhofer, Christoph, Ablasser, Klemens, Verheyen, Nicolas, Sourij, Caren, Kainz, Andreas, Wünsch, Gerit, Berghold, Andrea, Berghaus, Thomas M., Kanoun Schnur, Sadeek Sidney, Zirlik, Andreas, von Lewinski, Dirk

Source: Journal of Clinical Medicine; Dec2024, Vol. 13 Issue 23, p7324, 13p

Subject Terms: AIR pollutants, AIR pollution, CHRONIC obstructive pulmonary disease, MYOCARDIAL infarction, ACUTE coronary syndrome

Long-term efficacy and safety of drug-coated balloons versus drug-eluting stents for small coronary artery disease (BASKET-SMALL 2): 3-year follow-up of a randomised, non-inferiority trial

Authors: Ammann, Peter, Awad, Belal, Baumgartner, Margarete, Boehm, Michael, Bohl, Steffen, Bruch, Leonhard, Buckert, Dominik, Buser, Peter, Butter, Christian, Clever, Yvonne P., Cremers, Bodo, Cuculi, Florim, Dannberg, Gudrun, Erne, Paul, Ewen, Sebastian, Fahrni, Gregor, Franz, Marcus, Haager, Philipp, Harder-Allgoewer, Andrea, Hoffmann, Andreas, Höllriegel, Robert, Hölschermann, Frank, Jerichow, Timo, Joerg, Lucas, Kapos, Ioannis, Keweloh, Boris, Kherad, Behrouz, Kühne, Michael, Lauer, Bernward, Lenk, Karsten, Lenz, Corinna, Von Lewinski, Dirk, Linke, Axel, Luha, Olev, Maeder, Micha, Mahfoud, Felix, Mueller, Christian, Neuss, Michael, Niederl, Ella, Noutsias, Michel, Nuessli, Dominique, Oenal, Ismet, Otto, Sylvia, Paliskyte, Rima, Perl, Sabine, Pieske, Burkert, Plicht, Bjoern, Poerner, Tudor C, Richter, Stefan, Rickli, Hans, Riede, Florian, Roelli, Hans, Roettgen, Alexandra, Rohner, Franziska, Schirmer, Stephan, Schmidt, Albrecht, Schreiber, Matthias, Seidel, Mirko, Stephan, Frank-Peter, Sticherling, Christian, Struck, Berthold, Surber, Ralf, Tambor, Grit, Toggweiler, Stefan, Trachsel, Lukas, Twerenbold, Raphael, Wagner, Andreas, Wein, Bastian, Winkler, Sebastian, Winzer, Ephraim, Wolf, Alexander, Zellweger, Michael, Krackhardt, Florian, Zweiker, Robert, Jeger, Raban V ^*, Farah, Ahmed, Ohlow, Marc-Alexander, Mangner, Norman, Möbius-Winkler, Sven, Weilenmann, Daniel, Wöhrle, Jochen, Stachel, Georg, Markovic, Sinisa, Leibundgut, Gregor, Rickenbacher, Peter, Osswald, Stefan, Cattaneo, Marco, Gilgen, Nicole, Kaiser, Christoph, Scheller, Bruno

Source: In The Lancet 7-13 November 2020 396(10261):1504-1510

Empagliflozin protects heart from inflammation and energy depletion via AMPK activation

Authors: Koyani, Chintan N. ^*, Plastira, Ioanna, Sourij, Harald, Hallström, Seth, Schmidt, Albrecht, Rainer, Peter P., Bugger, Heiko, Frank, Saša, Malle, Ernst, von Lewinski, Dirk ^*

Source: In Pharmacological Research August 2020 158

Impact of EMpagliflozin on cardiac function and biomarkers of heart failure in patients with acute MYocardial infarction—The EMMY trial

Authors: Tripolt, Norbert J, Kolesnik, Ewald, Pferschy, Peter N, Verheyen, Nicolas, Ablasser, Klemens, Sailer, Sandra, Alber, Hannes, Berger, Rudolf, Kaulfersch, Carl, Leitner, Katharina, Lichtenauer, Michael, Mader, Arthur, Moertl, Deddo, Oulhaj, Abderrahim, Reiter, Christian, Rieder, Thomas, Saely, Christoph H., Siller-Matula, Jolanta, Weidinger, Franz, Zechner, Peter M, von Lewinski, Dirk, Sourij, Harald

Source: In American Heart Journal March 2020 221:39-47

A pragmatic approach to the use of inotropes for the management of acute and advanced heart failure: An expert panel consensus

Authors: Farmakis, Dimitrios, Agostoni, Piergiuseppe, Baholli, Loant, Bautin, Andrei, Comin-Colet, Josep, Crespo-Leiro, Maria G., Fedele, Francesco, García-Pinilla, Jose Manuel, Giannakoulas, George, Grigioni, Francesco, Gruchała, Marcin, Gustafsson, Finn, Harjola, Veli-Pekka, Hasin, Tal, Herpain, Antoine, Iliodromitis, Efstathios K., Karason, Kristjan, Kivikko, Matti, Liaudet, Lucas, Ljubas-Maček, Jana, Marini, Marco, Masip, Josep, Mebazaa, Alexandre, Nikolaou, Maria, Ostadal, Petr, Põder, Pentti, Pollesello, Piero, Polyzogopoulou, Eftihia, Pölzl, Gerhard, Tschope, Carsten, Varpula, Marjut, von Lewinski, Dirk, Vrtovec, Bojan, Yilmaz, Mehmet Birhan, Zima, Endre, Parissis, John

Source: In International Journal of Cardiology 15 December 2019 297:83-90