Soluble mannose receptor induces proinflammatory macrophage activation and metaflammation

Authors: Embgenbroich, Maria, van der Zande, Hendrik J. P., Hussaarts, Leonie, Schulte-Schrepping, Jonas, Pelgrom, Leonard R., García-Tardón, Noemí, Schlautmann, Laura, Stoetzel, Isabel, Händler, Kristian, Lambooij, Joost M., Zawistowska-Deniziak, Anna, Hoving, Lisa, de Ruiter, Karin, Wijngaarden, Marjolein A., Pijl, Hanno, van Dijk, Ko Willems, Everts, Bart, van Harmelen, Vanessa, Yazdanbakhsh, Maria, Schultze, Joachim L., Guigas, Bruno, Burgdorf, Sven

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Aug 01. 118(31), 1-10.

Access URL: https://www.jstor.org/stable/27052717

Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation.

Authors: Zhou, Enchen, Ge, Xiaoke, Nakashima, Hiroyuki, Li, Rumei, van der Zande, Hendrik J P, Liu, Cong, Li, Zhuang, Müller, Christoph, Bracher, Franz, Mohammed, Yassene, de Boer, Jan Freark, Kuipers, Folkert, Guigas, Bruno, Glass, Christopher K, Rensen, Patrick C N, Giera, Martin, Wang, Yanan

Source: EMBO Molecular Medicine; 8/7/2023, Vol. 15 Issue 8, p1-15, 15p

FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis.

Authors: Cong Liu, Schönke, Milena, Spoorenberg, Borah, Lambooij, Joost M., van der Zande, Hendrik J. P., Enchen Zhou, Tushuizen, Maarten E., Andreasson, Anne-Christine, Park, Andrew, Oldham, Stephanie, Uhrbom, Martin, Ahlstedt, Ingela, Yasuhiro Ikeda, Wallenius, Kristina, Xiao-Rong Peng, Guigas, Bruno, Boon, Mariëtte R., Yanan Wang, Rensen, Patrick C. N.

Source: eLife; 2/14/2023, p1-24, 24p

Dietary yeast-derived mannan oligosaccharides have immune-modulatory properties but do not improve high fat diet-induced obesity and glucose intolerance.

Authors: Hoving, Lisa R.^1,2 l.r.hoving@lumc.nl, van der Zande, Hendrik J. P.³, Pronk, Amanda^1,2, Guigas, Bruno^3,4, Willems van Dijk, Ko^1,2,5, van Harmelen, Vanessa^1,2

Source: PLoS ONE. 5/3/2018, Vol. 13 Issue 5, p1-17. 17p.

Subject Terms: *YEAST, *MANNANS, *GLUCOSE intolerance, *IMMUNE response, *HIGH-fat diet, *WHITE adipose tissue

The Mannose Receptor: From Endocytic Receptor and Biomarker to Regulator of (Meta)Inflammation.

Authors: van der Zande, Hendrik J. P., Nitsche, Dominik, Schlautmann, Laura, Guigas, Bruno, Burgdorf, Sven

Source: Frontiers in Immunology; 10/14/2021, Vol. 12, p1-13, 13p

Subject Terms: MANNOSE, ANTIGEN processing, MACROPHAGE activation, ANTIGEN presentation, BIOMARKERS

Effects of a novel polyphenol-rich plant extract on body composition, inflammation, insulin sensitivity, and glucose homeostasis in obese mice

Authors: van der Zande, Hendrik J. P., Lambooij, Joost M., Chavanelle, Vivien, Zawistowska-Deniziak, Anna, Otero, Yolanda, Otto, Frank, Lantier, Louise, McGuinness, Owen P., Le Joubioux, Florian, Giera, Martin, Maugard, Thierry, Peltier, Sébastien L., Sirvent, Pascal, Guigas, Bruno

Source: International Journal of Obesity (formerly International Journal of Obesity and Related Metabolic Disorders); 20210101, Issue: Preprints p1-12, 12p

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LKB1 expressed in dendritic cells governs the development and expansion of thymus-derived regulatory T cells

Authors: Pelgrom, Leonard R., Patente, Thiago A., Sergushichev, Alexey, Esaulova, Ekaterina, Otto, Frank, Ozir-Fazalalikhan, Arifa, van der Zande, Hendrik J. P., van der Ham, Alwin J., van der Stel, Stefan, Artyomov, Maxim N., Everts, Bart

Source: Cell Research; May 2019, Vol. 29 Issue: 5 p406-419, 14p

Weight cycling modifies the visceral adipose tissue and liver immune landscape without impacting whole-body insulin resistance in mice.

Authors: van der Zande, Hendrik J. P., Vrieling, Frank, Smeehuijzen, Lisa, Attema, Brecht, Jansen, Jenny, Kersten, Sander, Stienstra, Rinke

Source: Nederlands Tijdschrift voor Diabetologie (NTvD); Oct2023, Vol. 21 Issue 4, p52-52, 1/2p

The novel plant-based active principle Totum-448 decreases hepatic steatosis and inflammation in diet-induced NAFLD mice.

Authors: Lambooij, Joost M., Chavanelle, Vivien, van der Zande, Hendrik J. P., Otero, Yolanda F., Vallier, Marie, Otto, Frank, Schuurman, Robbie, Zaldumbide, Arnaud, Peltier, Sebastien L., Sirvent, Pascal, Guigas, Bruno

Source: Nederlands Tijdschrift voor Diabetologie (NTvD); Oct2023, Vol. 21 Issue 4, p34-34, 2/3p

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