Cerebral white matter hyperintensity volumes: Normative age- and sex-specific values from 15 population-based cohorts comprising 14,876 individuals

Authors: de Kort, Floor A.S., Vinke, Elisabeth J., van der Lelij, Ewoud J., Anblagan, Devasuda, Bastin, Mark E., Beiser, Alexa, Brodaty, Henry, Chaturvedi, Nishi, Cheng, Bastian, Cox, Simon R., DeCarli, Charles, Enzinger, Christian, Fletcher, Evan, Frayne, Richard, de Groot, Marius, Huang, Felicia, Ikram, M. Arfan, Jiang, Jiyang, Lam, Bonnie Y.K., Maillard, Pauline, Mayer, Carola, McCreary, Cheryl R., Mok, Vincent, Maniega, Susana Muñoz, Petersen, Marvin, Roshchupkin, Genady, Sachdev, Perminder S., Schmidt, Reinhold, Seiler, Stephan, Seshadri, Sudha, Sudre, Carole H., Thomalla, Götz, Twerenbold, Raphael, Valdés Hernández, Maria, Vernooij, Meike W., Wardlaw, Joanna M., Wen, Wei, Kuijf, Hugo J., Biessels, Geert Jan, Biesbroek, J. Matthijs

Source: In Neurobiology of Aging February 2025 146:38-47

Detection and localization of early- and late-stage cancers using platelet RNA

Authors: In ’t Veld, Sjors G.J.G., Arkani, Mohammad, Post, Edward, Antunes-Ferreira, Mafalda, D’Ambrosi, Silvia, Vessies, Daan C.L., Vermunt, Lisa, Vancura, Adrienne, Muller, Mirte, Niemeijer, Anna-Larissa N., Tannous, Jihane, Meijer, Laura L., Le Large, Tessa Y.S., Mantini, Giulia, Wondergem, Niels E., Heinhuis, Kimberley M., van Wilpe, Sandra, Smits, A. Josien, Drees, Esther E.E., Roos, Eva, Leurs, Cyra E., Tjon Kon Fat, Lee-Ann, van der Lelij, Ewoud J., Dwarshuis, Govert, Kamphuis, Maarten J., Visser, Lisanne E., Harting, Romee, Gregory, Annemijn, Schweiger, Markus W., Wedekind, Laurine E., Ramaker, Jip, Zwaan, Kenn, Verschueren, Heleen, Bahce, Idris, de Langen, Adrianus J., Smit, Egbert F., van den Heuvel, Michel M., Hartemink, Koen J., Kuijpers, Marijke J.E., oude Egbrink, Mirjam G.A., Griffioen, Arjan W., Rossel, Rafael, Hiltermann, T. Jeroen N., Lee-Lewandrowski, Elizabeth, Lewandrowski, Kent B., De Witt Hamer, Philip C., Kouwenhoven, Mathilde, Reijneveld, Jaap C., Leenders, William P.J., Hoeben, Ann, Verdonck-de Leeuw, Irma M., Leemans, C. René, Baatenburg de Jong, Robert J., Terhaard, Chris H.J., Takes, Robert P., Langendijk, Johannes A., de Jager, Saskia C., Kraaijeveld, Adriaan O., Pasterkamp, Gerard, Smits, Minke, Schalken, Jack A., Łapińska-Szumczyk, Sylwia, Łojkowska, Anna, Żaczek, Anna J., Lokhorst, Henk, van de Donk, Niels W.C.J., Nijhof, Inger, Prins, Henk-Jan, Zijlstra, Josée M., Idema, Sander, Baayen, Johannes C., Teunissen, Charlotte E., Killestein, Joep, Besselink, Marc G., Brammen, Lindsay, Bachleitner-Hofmann, Thomas, Mateen, Farrah, Plukker, John T.M., Heger, Michal, de Mast, Quirijn, Lisman, Ton, Pegtel, D. Michiel, Bogaard, Harm-Jan, Jassem, Jacek, Supernat, Anna, Mehra, Niven, Gerritsen, Winald, de Kroon, Cornelis D., Lok, Christianne A.R., Piek, Jurgen M.J., Steeghs, Neeltje, van Houdt, Winan J., Brakenhoff, Ruud H., Sonke, Gabe S., Verheul, Henk M., Giovannetti, Elisa, Kazemier, Geert, Sabrkhany, Siamack, Schuuring, Ed, Sistermans, Erik A., Wolthuis, Rob, Meijers-Heijboer, Hanne, Dorsman, Josephine, Oudejans, Cees, Ylstra, Bauke, Westerman, Bart A., van den Broek, Daan, Koppers-Lalic, Danijela, Wesseling, Pieter, Nilsson, R. Jonas A., Vandertop, W. Peter, Noske, David P., Tannous, Bakhos A., Sol, Nik, Best, Myron G., Wurdinger, Thomas

Source: In Cancer Cell 12 September 2022 40(9):999-1009

Multi-omics analyses of MEN1 missense mutations identify disruption of menin–MLL and menin–JunD interactions as critical requirements for molecular pathogenicity.

Authors: Dreijerink, Koen M. A., Ozyerli-Goknar, Ezgi, Koidl, Stefanie, van der Lelij, Ewoud J., van den Heuvel, Priscilla, Kooijman, Jeffrey J., Biniossek, Martin L., Rodenburg, Kees W., Nizamuddin, Sheikh, Timmers, H. T. Marc

Source: Epigenetics & Chromatin; 8/9/2022, Vol. 15 Issue 1, p1-16, 16p

Subject Terms: MISSENSE mutation, MUTANT proteins, TRANSCRIPTION factors, AP-1 transcription factor, MASS spectrometry, GENETIC mutation