Borrelia burgdorferi sensu lato inhibits CIITA transcription through pSTAT3 activation and enhanced SOCS1 and SOCS3 expression leading to limited IFN-γ production

Authors: Brouwer, Michelle A.E. ^a, Karami, Zara ^a, Keating, Samuel T. ^{a, b}, Vrijmoeth, Hedwig ^a, Lemmers, Heidi L.M. ^a, Dijkstra, Helga ^a, van de Veerdonk, Frank L. ^a, Lupse, Mihaela ^c, ter Hofstede, Hadewych J.M. ^a, Netea, Mihai G. ^{a, d}, Joosten, Leo A.B. ^{a, e, ⁎}

Source: In Ticks and Tick-borne Diseases January 2025 16(1)

Regulation of plasma soluble receptors of TNF and IL-1 in patients with COVID-19 differs from that observed in sepsis

Authors: Aksu, Muhammed D., van der Ent, Tijmen, Zhang, Zhenhua, Riza, Anca L., de Nooijer, Aline H., Ricaño-Ponce, Isis, Janssen, Nico, Engel, Job J., Streata, Ioana, Dijkstra, Helga, Lemmers, Heidi, Grondman, Inge, Koeken, Valerie A.C.M., Antoniadou, Eleni, Antonakos, Nikolaos, van de Veerdonk, Frank L., Li, Yang, Giamarellos-Bourboulis, Evangelos J., Netea, Mihai G., Ziogas, Athanasios

Source: In Journal of Infection December 2024 89(6)

Clinical exome sequencing data from patients with inborn errors of immunity: Cohort level diagnostic yield and the benefit of systematic reanalysis

Authors: Arts, Rob J.W., Bijker, Else M., Bruno, Mariolina, Hobo, Willemijn, Hoppenreijs, Esther, de Jonge, Marien I., van Laarhoven, Arjan, van der Molen, Renate, Oud, Manon, Schatorje, Ellen J.H., Smeets, Ruben, Sprenkeler, Evelien G.G., Stol, Kim, Verhagen, Lilly M., Zonneveld-Huijssoon, Evelien, Vorsteveld, Emil E., Van der Made, Caspar I., Smeekens, Sanne P., Schuurs-Hoeijmakers, Janneke H., Astuti, Galuh, Diepstra, Heleen, Gilissen, Christian, Hoenselaar, Evelien, Janssen, Alice, van Roozendaal, Kees, Engelen, Jettie Sikkema-van, Steyaert, Wouter, Weiss, Marjan M., Yntema, Helger G., Mantere, Tuomo, AlZahrani, Mofareh S., van Aerde, Koen, Derfalvi, Beata, Faqeih, Eissa Ali, Henriet, Stefanie S.V., van Hoof, Elise, Idressi, Eman, Issekutz, Thomas B., Jongmans, Marjolijn C.J., Keski-Filppula, Riikka, Krapels, Ingrid, te Loo, Maroeska, Mulders-Manders, Catharina M., ten Oever, Jaap, Potjewijd, Judith, Sarhan, Nora Tarig, Slot, Marjan C., Terhal, Paulien A., Thijs, Herman, Vandersteen, Anthony, Vanhoutte, Els K., van de Veerdonk, Frank, van Well, Gijs, Netea, Mihai G., Simons, Annet, Hoischen, Alexander

Source: In Clinical Immunology November 2024 268

Damping excessive viral-induced IFN-γ rescues the impaired anti-Aspergillus host immune response in influenza-associated pulmonary aspergillosis

Authors: Seldeslachts, Laura, Staels, Frederik, Gkountzinopoulou, Marina, Jacobs, Cato, Tielemans, Birger, Vanhoffelen, Eliane, Reséndiz-Sharpe, Agustin, De Herdt, Lander, Haughton, Jeason, Prezzemolo, Teresa, Burton, Oliver, Feys, Simon, van de Veerdonk, Frank L., Carvalho, Agostinho, Naesens, Lieve, Matthys, Patrick, Lagrou, Katrien, Verbeken, Erik, Chamilos, Georgios, Wauters, Joost, Humblet-Baron, Stephanie, Vande Velde, Greetje

Source: In eBioMedicine October 2024 108

Influenza-associated and COVID-19-associated pulmonary aspergillosis in critically ill patients

Authors: Feys, Simon ^*, Carvalho, Agostinho, Clancy, Cornelius J, Gangneux, Jean-Pierre, Hoenigl, Martin, Lagrou, Katrien, Rijnders, Bart J A, Seldeslachts, Laura, Vanderbeke, Lore, van de Veerdonk, Frank L, Verweij, Paul E, Wauters, Joost

Source: In The Lancet Respiratory Medicine September 2024 12(9):728-742

Epigenetic, transcriptional, and functional characterization of myeloid cells in familial Mediterranean fever

Authors: Röring, Rutger J., Li, Wenchao, Liu, Ruiqi, Bruno, Mariolina, Zhang, Bowen, Debisarun, Priya A., Gaal, Orsolya, Badii, Medeea, Klück, Viola, Moorlag, Simone J.C.F.M., van de Veerdonk, Frank, Li, Yang, Joosten, Leo A.B., Netea, Mihai G.

Source: In iScience 19 April 2024 27(4)

Lower respiratory tract single-cell RNA sequencing and neutrophil extracellular trap profiling of COVID-19-associated pulmonary aspergillosis: a single centre, retrospective, observational study

Authors: Feys, Simon, Vanmassenhove, Sam, Kraisin, Sirima, Yu, Karen, Jacobs, Cato, Boeckx, Bram, Cambier, Seppe, Cunha, Cristina, Debaveye, Yves, Gonçalves, Samuel M, Hermans, Greet, Humblet-Baron, Stephanie, Jansen, Sander, Lagrou, Katrien, Meersseman, Philippe, Neyts, Johan, Peetermans, Marijke, Rocha-Pereira, Joana, Schepers, Rogier, Spalart, Valérie, Starick, Marick R, Thevissen, Karin, Van Brussel, Thomas, Van Buyten, Tina, Van Mol, Pierre, Vandenbriele, Christophe, Vanderbeke, Lore, Wauters, Els, Wilmer, Alexander, Van Weyenbergh, Johan, Van De Veerdonk, Frank L, Carvalho, Agostinho, Proost, Paul, Martinod, Kimberly, Lambrechts, Diether, Wauters, Joost

Source: In The Lancet Microbe March 2024 5(3):e247-e260

The impact of BNT162b2 mRNA vaccine on adaptive and innate immune responses

Authors: Föhse, Konstantin, Geckin, Büsra, Zoodsma, Martijn, Kilic, Gizem, Liu, Zhaoli, Röring, Rutger J., Overheul, Gijs J., van de Maat, Josephine, Bulut, Ozlem, Hoogerwerf, Jacobien J., ten Oever, Jaap, Simonetti, Elles, Schaal, Heiner, Adams, Ortwin, Müller, Lisa, Ostermann, Philipp Niklas, van de Veerdonk, Frank L., Joosten, Leo A.B., Haagmans, Bart L., van Crevel, Reinout, van Rij, Ronald P., GeurtsvanKessel, Corine, de Jonge, Marien I., Li, Yang, Domínguez-Andrés, Jorge, Netea, Mihai G.

Source: In Clinical Immunology October 2023 255

Transient anti-cytokine autoantibodies superimpose the hyperinflammatory response in Kawasaki disease and multisystem inflammatory syndrome in children: a comparative cohort study on correlates of disease

Authors: Hendriks, T., Felderhof, M.K., Weggelaar, N.M., Filippini, L., Rozendaal, L., Groeneweg, M., Nuboer, R., Bruijn, M., Dolman, K.M., Noordzij, J.G., de Winter, J.P., Vlieger, A.M., Plötz, F.B., Delemarre, L.C., Netea, Stejara A., Biesbroek, Giske, van Stijn, Diana, Ijspeert, Hanna, van der Made, Caspar I., Jansen, Machiel H., Geissler, Judy, van den Berg, J.M. (Merlijn), van der Kuip, Martijn, Gruppen, Mariken P., Schonenberg-Meinema, Dieneke, Kapitein, Berber, van Furth, A.M. (Marceline) Tutu, Nagelkerke, Sietse Q., Pajkrt, Dasja, Plötz, Frans B., den Boer, M.E.J. (Lisette), Landman, Gijs W., van Houten, Marlies A., Goetschalckx, Ines, Toonen, Erik J.M., van de Veerdonk, Frank L., Kuipers, Irene M., Dik, Willem A., Kuijpers, Taco W.

Source: In eBioMedicine September 2023 95

Incidence, risk factors and pre-emptive screening for COVID-19 associated pulmonary aspergillosis in an era of immunomodulant therapy

Authors: van Grootveld, Rebecca, van der Beek, Martha T., Janssen, Nico A.F., Ergün, Mehmet, van Dijk, Karin, Bethlehem, Carina, Stads, Susanne, van Paassen, Judith, Heunks, Leo M.A., Bouman, Catherine S.C., Reijers, Monique H.E., Brüggeman, Roger J., van de Veerdonk, Frank L., van Bree, Sjoerd H.W., van den Berg, Charlotte H.S.B., Kuindersma, Marnix, Wauters, Joost, Beishuizen, Albertus, Verweij, Paul E., Schouten, Jeroen A.

Source: In Journal of Critical Care August 2023 76

Dimethyl itaconate induces long-term innate immune responses and confers protection against infection

Authors: Ferreira, Anaísa V., Kostidis, Sarantos, Groh, Laszlo A., Koeken, Valerie A.C.M., Bruno, Mariolina, Baydemir, Ilayda, Kilic, Gizem, Bulut, Özlem, Andriopoulou, Theano, Spanou, Victoria, Synodinou, Kalliopi D., Gkavogianni, Theologia, Moorlag, Simone J.C.F.M., Charlotte de Bree, L., Mourits, Vera P., Matzaraki, Vasiliki, Koopman, Werner J.H., van de Veerdonk, Frank L., Renieris, Georgios, Giera, Martin, Giamarellos-Bourboulis, Evangelos J., Novakovic, Boris, Domínguez-Andrés, Jorge

Source: In Cell Reports 27 June 2023 42(6)

Bacillus Calmette-Guérin vaccine for prevention of COVID-19 and other respiratory tract infections in older adults with comorbidities: a randomized controlled trial

Authors: Aardenburg-van Huisstede, Astrid, Ammerlaan, Heidi S.M., Boersma, Willem G., Bonten, Marc J.M., van den Bosch, Maurice A.A.J., Brinkman, Kees, Bruijning-Verhagen, Patricia C.J., van Crevel, Reinout, Delsing, Corine, ten Doesschaten, Thijs, Dofferhoff, Anton S.M., Duijkers, Ruud, Fohse, Konstantin, Grobusch, Martin P., Groenwold, Rolf H.H., de Haas, Corine, Hassing, Robert-Jan, de Hoog, Marieke L.A., Hoogerwerf, Jacobien J., Huijts, Susanne M., van Hylckama-Vlieg, Astrid, Jong, Eefje, de Jong, Hanna K., Knap, Martijn, Koekenbier, Eva L., Koenders, Michael, Kouijzer, Ilse J.E., Kramer, Henk, van de Laar, Roel, Lalmohamed, Arief, Lensen, Karel-Jan D.F., Lijfering, Willem M., van de Maat, Josephine S., Magdelijns, Fabienne, Meek, Bob, Middelburg, Rutger A., Moeniralam, Hazra S., Mooijaart, Simon P., van Munster, Barbara C., Netea, Mihai G., van Nieuwkoop, Cees, ten Oever, Jaap, Oosterheert, Jan Jelrik, Goossens, Marc Padros, Peters, Vincent, Postma, Douwe F., Pouw, Niels, Reesink, Herre J., de Regt, Marieke J.A., van der Reijden, Anneli C.J., Rosendaal, Frits R., Schaakxs, R., Slieker, Kitty, Slingerland, Robbert J., van Sluis, Nicolette L.J., Stehouwer, Coen D.A., van de Veerdonk, Frank, Verbon, Annelies, van Werkhoven, C.H. (Henri), van de Wijgert, Janneke H.H., Werkhoven, C.H. (Henri) van

Source: In Clinical Microbiology and Infection June 2023 29(6):781-788

Lung epithelial and myeloid innate immunity in influenza-associated or COVID-19-associated pulmonary aspergillosis: an observational study

Authors: Feys, Simon, Gonçalves, Samuel M ^*, Khan, Mona ^*, Choi, Sumin ^*, Boeckx, Bram, Chatelain, Denis, Cunha, Cristina, Debaveye, Yves, Hermans, Greet, Hertoghs, Marjan, Humblet-Baron, Stephanie, Jacobs, Cato, Lagrou, Katrien, Marcelis, Lukas, Maizel, Julien, Meersseman, Philippe, Nyga, Rémy, Seldeslachts, Laura, Starick, Marick Rodrigues, Thevissen, Karin, Vandenbriele, Christophe, Vanderbeke, Lore, Vande Velde, Greetje, Van Regenmortel, Niels, Vanstapel, Arno, Vanmassenhove, Sam, Wilmer, Alexander, Van De Veerdonk, Frank L, De Hertogh, Gert, Mombaerts, Peter, Lambrechts, Diether, Carvalho, Agostinho, Van Weyenbergh, Johan, Wauters, Joost ^*

Source: In The Lancet Respiratory Medicine December 2022 10(12):1147-1159

Human variation in population-wide gene expression data predicts gene perturbation phenotype

Authors: Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Carraro, Caterina, Sun, Laura L., Reiz, Benedikt, Gemünd, Ioanna, Saglam, Adem, Rahmouni, Souad, Georges, Michel, Arts, Peer, Hoischen, Alexander, Joosten, Leo A.B., van de Veerdonk, Frank L., Netea, Mihai G., Händler, Kristian, Mukherjee, Sach, Ulas, Thomas, Schultze, Joachim L., Aschenbrenner, Anna C.

Source: In iScience 18 November 2022 25(11)

Immunological Effects of Anti‒IL-17/12/23 Therapy in Patients with Psoriasis Complicated by Candida Infections

Authors: Bruno, Mariolina, Davidson, Linda, Koenen, Hans J.P.M., van den Reek, Juul M.P.A., van Cranenbroek, Bram, de Jong, Elke M.G.J., van de Veerdonk, Frank L., Kullberg, Bart-Jan, Netea, Mihai G.

Source: In Journal of Investigative Dermatology November 2022 142(11):2929-2939

The Renin-Angiotensin System in Acute Lung Injury*

Authors: Lawler, Patrick R., Derde, Lennie P. G., McVerry, Bryan J., Russell, James A., van de Veerdonk, Frank L.

Source: Critical care medicine. 50(9):1411-1415

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195548216.0x000001&indx=1&recIds=ETOCvdc_100195548216.0x000001

Immunogenicity of the mRNA-1273 COVID-19 vaccine in adult patients with inborn errors of immunity

Authors: van Leeuwen, Leanne P.M., GeurtsvanKessel, Corine H., Ellerbroek, Pauline M., de Bree, Godelieve J., Potjewijd, Judith, Rutgers, Abraham, Jolink, Hetty, van de Veerdonk, Frank, van Gorp, Eric C.M., de Wilt, Faye, Bogers, Susanne, Gommers, Lennert, Geers, Daryl, Bruns, Anke H.W., Leavis, Helen L., van Haga, Jelle W., Lemkes, Bregtje A., van der Veen, Annelou, de Kruijf-Bazen, S.F.J., van Paassen, Pieter, de Leeuw, Karina, van de Ven, Annick A.J.M., Verbeek-Menken, Petra H., van Wengen, Annelies, Arend, Sandra M., Ruten-Budde, Anja J., van der Ent, Marianne W., van Hagen, P. Martin, Sanders, Rogier W., Grobben, Marloes, van der Straten, Karlijn, Burger, Judith A., Poniman, Meliawati, Nierkens, Stefan, van Gils, Marit J., de Vries, Rory D., Dalm, Virgil A.S.H.

Source: Journal of allergy and clinical immunology. 149(6):1949-1957

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164767535.0x000001&indx=1&recIds=ETOCvdc_100164767535.0x000001

Natural resistance against infections: focus on COVID-19

Authors: Netea, Mihai G., Domínguez-Andrés, Jorge, van de Veerdonk, Frank L., van Crevel, Reinout, Pulendran, Bali, van der Meer, Jos W.M.

Source: Trends in immunology. 43(2):106-116

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155014057.0x000001&indx=1&recIds=ETOCvdc_100155014057.0x000001

Genetic determinants of fungi-induced ROS production are associated with the risk of invasive pulmonary aspergillosis

Authors: Matzaraki, Vasiliki, Beno, Alexandra, Jaeger, Martin, Gresnigt, Mark S., Keur, Nick, Boahen, Collins, Cunha, Cristina, Gonçalves, Samuel M., Leite, Luis, Lacerda, João F., Campos, António, Jr., van de Veerdonk, Frank L., Joosten, Leo, Netea, Mihai G., Carvalho, Agostinho, Kumar, Vinod

Source: In Redox Biology September 2022 55

Risk of candidiasis associated with interleukin-17 inhibitors: A real-world observational study of multiple independent sources

Authors: Davidson, Linda, van den Reek, Juul M.P.A., Bruno, Mariolina, van Hunsel, Florence, Herings, Ron M.C., Matzaraki, Vasiliki, Boahen, Collins K., Kumar, Vinod, Groenewoud, Hans M.M., van de Veerdonk, Frank L., Netea, Mihai G., de Jong, Elke M.G.J., Kullberg, Bart Jan

Source: In The Lancet Regional Health - Europe February 2022 13