A pan-cancer analysis of the microbiome in metastatic cancer

Authors: Battaglia, Thomas W., Mimpen, Iris L., Traets, Joleen J.H., van Hoeck, Arne, Zeverijn, Laurien J., Geurts, Birgit S., de Wit, Gijs F., Noë, Michaël, Hofland, Ingrid, Vos, Joris L., Cornelissen, Sten, Alkemade, Maartje, Broeks, Annegien, Zuur, Charlotte L., Cuppen, Edwin, Wessels, Lodewyk, van de Haar, Joris, Voest, Emile

Source: In Cell 25 April 2024 187(9):2324-2335

Identifying Epistasis in Cancer Genomes: A Delicate Affair

Authors: van de Haar, Joris, Canisius, Sander, Yu, Michael K., Voest, Emile E., Wessels, Lodewyk F.A., Ideker, Trey

Source: In Cell 30 May 2019 177(6):1375-1383

Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids

Authors: Dijkstra, Krijn K., Cattaneo, Chiara M., Weeber, Fleur, Chalabi, Myriam, van de Haar, Joris, Fanchi, Lorenzo F., Slagter, Maarten, van der Velden, Daphne L., Kaing, Sovann, Kelderman, Sander, van Rooij, Nienke, van Leerdam, Monique E., Depla, Annekatrien, Smit, Egbert F., Hartemink, Koen J., de Groot, Rosa, Wolkers, Monika C., Sachs, Norman, Snaebjornsson, Petur, Monkhorst, Kim, Haanen, John, Clevers, Hans, Schumacher, Ton N., Voest, Emile E.

Source: In Cell 6 September 2018 174(6):1586-1598

MHC-I Genotype Restricts the Oncogenic Mutational Landscape

Authors: Marty, Rachel, Kaabinejadian, Saghar, Rossell, David, Slifker, Michael J., van de Haar, Joris, Engin, Hatice Billur, de Prisco, Nicola, Ideker, Trey, Hildebrand, William H., Font-Burgada, Joan, Carter, Hannah

Source: In Cell 30 November 2017 171(6):1272-1283

Multi-omic analysis identifies hypoalbuminemia as independent biomarker of poor outcome upon PD-1 blockade in metastatic melanoma.

Authors: Leek, Lindsay V. M., Notohardjo, Jessica C. L., de Joode, Karlijn, Velker, Eline L., Haanen, John B. A. G., Suijkerbuijk, Karijn P. M., Aarts, Maureen J. B., de Groot, Jan Willem B., Kapiteijn, Ellen, van den Berkmortel, Franchette W. P. J., Westgeest, Hans M., de Gruijl, Tanja D., Retel, Valesca P., Cuppen, Edwin, van der Veldt, Astrid A. M., Labots, Mariette, Voest, Emile E., van de Haar, Joris, van den Eertwegh, Alfons J. M.

Source: Scientific Reports; 5/16/2024, Vol. 14 Issue 1, p1-11, 11p

Subject Terms: MELANOMA, PROGRAMMED cell death 1 receptors, LIVER metastasis, BIOMARKERS, METASTASIS, PROGRESSION-free survival

Neoadjuvant atezolizumab plus chemotherapy in gastric and gastroesophageal junction adenocarcinoma: the phase 2 PANDA trial

Authors: Verschoor, Yara L., van de Haar, Joris, van den Berg, José G., van Sandick, Johanna W., Kodach, Liudmila L., van Dieren, Jolanda M., Balduzzi, Sara, Grootscholten, Cecile, IJsselsteijn, Marieke E., Veenhof, Alexander A. F. A., Hartemink, Koen J., Vollebergh, Marieke A., Jurdi, Adham, Sharma, Shruti, Spickard, Erik, Owers, Emilia C., Bartels-Rutten, Annemarieke, den Hartog, Peggy, de Miranda, Noel F. C. C., van Leerdam, Monique E., Haanen, John B. A. G., Schumacher, Ton N., Voest, Emile E., Chalabi, Myriam

Source: Nature Medicine; 20240101, Issue: Preprints p1-12, 12p

γδ T cells are effectors of immunotherapy in cancers with HLA class I defects.

Authors: de Vries, Natasja L., van de Haar, Joris, Veninga, Vivien, Chalabi, Myriam, Ijsselsteijn, Marieke E., van der Ploeg, Manon, van den Bulk, Jitske, Ruano, Dina, van den Berg, Jose G., Haanen, John B., Zeverijn, Laurien J., Geurts, Birgit S., de Wit, Gijs F., Battaglia, Thomas W., Gelderblom, Hans, Verheul, Henk M. W., Schumacher, Ton N., Wessels, Lodewyk F. A., Koning, Frits, de Miranda, Noel F. C. C.

Source: Nature; Jan2023, Vol. 613 Issue 7945, p743-750, 8p

Functional precision oncology using patient-derived assays: bridging genotype and phenotype

Authors: van Renterghem, Allard W. J., van de Haar, Joris, Voest, Emile E.

Source: Nature Reviews Clinical Oncology; May 2023, Vol. 20 Issue: 5 p305-317, 13p

Codon-specific KRASmutations predict survival benefit of trifluridine/tipiracil in metastatic colorectal cancer

Authors: van de Haar, Joris, Ma, Xuhui, Ooft, Salo N., van der Helm, Pim W., Hoes, Louisa R., Mainardi, Sara, Pinato, David J., Sun, Kristi, Salvatore, Lisa, Tortora, Giampaolo, Zurlo, Ina Valeria, Leo, Silvana, Giampieri, Riccardo, Berardi, Rossana, Gelsomino, Fabio, Merz, Valeria, Mazzuca, Federica, Antonuzzo, Lorenzo, Rosati, Gerardo, Stavraka, Chara, Ross, Paul, Rodriquenz, Maria Grazia, Pavarana, Michele, Messina, Carlo, Iveson, Timothy, Zoratto, Federica, Thomas, Anne, Fenocchio, Elisabetta, Ratti, Margherita, Depetris, Ilaria, Cergnul, Massimiliano, Morelli, Cristina, Libertini, Michela, Parisi, Alessandro, De Tursi, Michele, Zanaletti, Nicoletta, Garrone, Ornella, Graham, Janet, Longarini, Raffaella, Gobba, Stefania Maria, Petrillo, Angelica, Tamburini, Emiliano, La Verde, Nicla, Petrelli, Fausto, Ricci, Vincenzo, Wessels, Lodewyk F. A., Ghidini, Michele, Cortellini, Alessio, Voest, Emile E., Valeri, Nicola

Source: Nature Medicine; March 2023, Vol. 29 Issue: 3 p605-614, 10p

Patient-Derived Organoid Models of Human Neuroendocrine Carcinoma.

Authors: Dijkstra, Krijn K., van den Berg, José G., Weeber, Fleur, van de Haar, Joris, Velds, Arno, Kaing, Sovann, Peters, Dennis D. G. C., Eskens, Ferry A. L. M., de Groot, Derk-Jan A., Tesselaar, Margot E. T., Voest, Emile E.

Source: Frontiers in Endocrinology; 3/11/2021, Vol. 11, pN.PAG-N.PAG, 11p

Subject Terms: CELL culture, CARCINOMA, THERAPEUTICS, ANIMAL models in research, NUCLEOTIDE sequence

Limited evolution of the actionable metastatic cancer genome under therapeutic pressure

Authors: van de Haar, Joris, Hoes, Louisa R., Roepman, Paul, Lolkema, Martijn P., Verheul, Henk M. W., Gelderblom, Hans, de Langen, Adrianus J., Smit, Egbert F., Cuppen, Edwin, Wessels, Lodewyk F. A., Voest, Emile E.

Source: Nature Medicine; September 2021, Vol. 27 Issue: 9 p1553-1563, 11p

Caring for patients with cancer in the COVID-19 era

Authors: van de Haar, Joris, Hoes, Louisa R., Coles, Charlotte E., Seamon, Kenneth, Fröhling, Stefan, Jäger, Dirk, Valenza, Franco, de Braud, Filippo, De Petris, Luigi, Bergh, Jonas, Ernberg, Ingemar, Besse, Benjamin, Barlesi, Fabrice, Garralda, Elena, Piris-Giménez, Alejandro, Baumann, Michael, Apolone, Giovanni, Soria, Jean Charles, Tabernero, Josep, Caldas, Carlos, Voest, Emile E.

Source: Nature Medicine; May 2020, Vol. 26 Issue: 5 p665-671, 7p

Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients.

Authors: Ooft, Salo N., Weeber, Fleur, Dijkstra, Krijn K., McLean, Chelsea M., Kaing, Sovann, van Werkhoven, Erik, Schipper, Luuk, Hoes, Louisa, Vis, Daniel J., van de Haar, Joris, Prevoo, Warner, Snaebjornsson, Petur, van der Velden, Daphne, Klein, Michelle, Chalabi, Myriam, Boot, Henk, van Leerdam, Monique, Bloemendal, Haiko J., Beerepoot, Laurens V., Wessels, Lodewyk

Source: Science Translational Medicine; 10/9/2019, Vol. 11 Issue 513, p1-9, 9p

Subject Terms: COLORECTAL cancer, CANCER patients, METASTASIS, CANCER chemotherapy, ORGANOIDS

Advancing molecular tumour boards: highly needed to maximise the impact of precision medicine

Authors: van de Haar, Joris, Hoes, Louisa, Voest, Emile

Source: In ESMO Open 2019 4(2)

Author Correction: Neoadjuvant atezolizumab plus chemotherapy in gastric and gastroesophageal junction adenocarcinoma: the phase 2 PANDA trial

Authors: Verschoor, Yara L., van de Haar, Joris, van den Berg, José G., van Sandick, Johanna W., Kodach, Liudmila L., van Dieren, Jolanda M., Balduzzi, Sara, Grootscholten, Cecile, IJsselsteijn, Marieke E., Veenhof, Alexander A. F. A., Hartemink, Koen J., Vollebergh, Marieke A., Jurdi, Adham, Sharma, Shruti, Spickard, Erik, Owers, Emilia C., Bartels-Rutten, Annemarieke, den Hartog, Peggy, de Miranda, Noel F. C. C., van Leerdam, Monique E., Haanen, John B. A. G., Schumacher, Ton N., Voest, Emile E., Chalabi, Myriam

Source: Nature Medicine; 20240101, Issue: Preprints p1-1, 1p

Third-Line Therapy in Metastatic Colorectal Cancer.

Authors: van de Haar, Joris¹ j.vd.haar@nki.nl, Valeri, Nicola², Voest, Emile E.¹

Source: New England Journal of Medicine. 7/13/2023, Vol. 389 Issue 2, p190-190. 2/3p.

Subject Terms: *COLORECTAL cancer, *METASTASIS

Efficacy and predictors of response of nivolumab in treatment-refractory MSI solid tumors: Results of a tumor-agnostic DRUP cohort.

Authors: Geurts, Birgit, Zeverijn, Laurien Joanna, Battaglia, Thomas W., van de Haar, Joris, van Berge Henegouwen, Jade M., Hoes, Louisa Rose, van der Wijngaart, Hanneke, Roepman, Paul, de Leng, Wendy W.J., Jansen, Anne M.L., van der Noort, Vincent, Chalabi, Myriam, Devriese, Lot A., Van Herpen, Carla M.L.-, Gelderblom, Hans, Verheul, Henk M.W., Voest, Emile E.

Source: Journal of Clinical Oncology; 2023 Supplement 16, Vol. 41, p2590-2590, 1p

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Author Correction: Caring for patients with cancer in the COVID-19 era

Authors: van de Haar, Joris, Hoes, Louisa R., Coles, Charlotte E., Seamon, Kenneth, Fröhling, Stefan, Jäger, Dirk, Valenza, Franco, de Braud, Filippo, De Petris, Luigi, Bergh, Jonas, Ernberg, Ingemar, Besse, Benjamin, Barlesi, Fabrice, Garralda, Elena, Piris-Giménez, Alejandro, Baumann, Michael, Apolone, Giovanni, Soria, Jean Charles, Tabernero, Josep, Caldas, Carlos, Voest, Emile E.

Source: Nature Medicine; July 2020, Vol. 26 Issue: 7 p1146-1146, 1p

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