Exploration of the plasma proteomic profile of patients at risk of thromboembolic events

Authors: Arbous, M. Sesmu, van den Berg, Bernard M., Cannegieter, Suzanne, Cobbaert, Christa M., van der Does, Anne M., van Dongen, Jacques J.M., Eikenboom, Jeroen, Feltkamp, Mariet C.W., Geluk, Annemieke, Goeman, Jelle J., Giera, Martin, Hankemeier, Thomas, Heemskerk, Mirjam H.M., Hiemstra, Pieter S., Hokke, Cornelis H., Janse, Jacqueline J., Jochems, Simon P., Joosten, Simone A., Kikkert, Marjolein, Lamont, Lieke, Manniën, Judith, Ottenhoff, Tom H.M., Pongracz, T., del Prado, Michael R., Roestenberg, Meta, Roukens, Anna H.E., Smits, Hermelijn H., Snijder, Eric J., Staal, Frank J.T., Trouw, Leendert A., Tsonaka, Roula, Verhoeven, Aswin, Visser, Leo G., de Vries, Jutte J.C., van Westerloo, David J., Wigbers, Jeanette, van der Wijk, Henk J., van Wissen, Robin C., Wuhrer, Manfred, Yazdanbakhsh, Maria, Zlei, Mihaela, Smit, Eva R. ¹, Kreft, Iris C. ¹, Camilleri, Eleonora ², Burggraaf-van Delft, J. Louise I. ², van Rein, Nienke ^{2, 3}, van Vlijmen, Bart J.M. ⁴, Hulshof, Anne-Marije ^{5, 6}, van Bussel, Bas C.T. ^{5, 7}, van Rosmalen, Frank ^{5, 7}, van der Zwaan, Carmen ¹, van de Berg, Tom ^{5, 8}, Henskens, Yvonne ^{5, 6}, Cate, Hugo ten ^{5, 8}, Coutinho, Jonathan M. ⁹, Kruip, Marieke J.H.A. ^{10, 11}, Eikenboom, Jeroen J.C. ⁴, Hoogendijk, Arie J. ¹, Cannegieter, Suzanne C. ^{2, 4}, van den Biggelaar, Maartje ^{1, ∗}

Source: In Research and Practice in Thrombosis and Haemostasis December 2024

Silencing of the von Willebrand factor gene in proatherothrombotic APOE∗3-Leiden.CETP transgenic mice

Authors: Jongejan, Yvonne K. ¹, Dirven, Richard J. ¹, Schrader Echeverri, Elisa ², de Jong, Anke J.L. ¹, Pronk, Amanda C.M. ³, Kooijman, Sander ³, Rensen, Patrick C.N. ³, Dahlman, James E. ², Eikenboom, Jeroen C.J. ¹, van Vlijmen, Bart J.M. ^{1, ∗}

Source: In Research and Practice in Thrombosis and Haemostasis January 2025 9(1)

The effects of an aggressive breast tumor on thrombosis after antithrombin downregulation in a hypercoagulable mouse model

Authors: Ünlü, Betül, Heestermans, Marco, Laghmani, El Houari, Buijs, Jeroen T., van den Akker, Rob F.P., van Vlijmen, Bart J.M., Versteeg, Henri H. ^⁎

Source: In Thrombosis Research December 2024 244

Quantitative protein mass spectrometry for multiplex measurement of coagulation and fibrinolytic proteins towards clinical application: What, why and how?

Authors: Camilleri, Eleonora, Kruijt, Mirjam, den Exter, Paul L., Cannegieter, Suzanne C., van Rein, Nienke, Cobbaert, Christa M., van Vlijmen, Bart J.M., Ruhaak, L. Renee

Source: In Thrombosis Research September 2024 241

Impact of allele-selective silencing of von Willebrand factor in mice based on a single nucleotide allelic difference in von Willebrand factor

Authors: Jongejan, Yvonne K., Linthorst, Noa A., Schrader Echeverri, Elisa, Laan, Sebastiaan N.J., Dirven, Richard J., Dahlman, James E., van Vlijmen, Bart J.M., Denis, Cécile V., Eikenboom, Jeroen C.J.

Source: In Thrombosis Research April 2024 236:201-208

Influence of rosuvastatin on apolipoproteins and coagulation factor levels: Results from the STAtin Reduce Thrombophilia trial

Authors: Camilleri, Eleonora, van Rein, Nienke, van Vlijmen, Bart J.M., Biedermann, Joseph S., Kruip, Marieke J.H.A., Leebeek, Frank W., van der Meer, Felix J., Cobbaert, Christa M., Cannegieter, Suzanne C., Lijfering, Willem M.

Source: In Research and Practice in Thrombosis and Haemostasis February 2023 7(2)

Absence of COVID-19-associated changes in plasma coagulation proteins and pulmonary thrombosis in the ferret model

Authors: Kreft, Iris C., Winiarczyk, Roy R.A., Tanis, Fric J., van der Zwaan, Carmen, Schmitz, Katharina S., Hoogendijk, Arie J., de Swart, Rik L., Moscona, Anne, Porotto, Matteo, Salvatori, Daniela C.F., de Vries, Rory D., de Maat, Moniek P.M., van den Biggelaar, Maartje, van Vlijmen, Bart J.M.

Source: Thrombosis research. 210:6-11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154778664.0x000001&indx=1&recIds=ETOCvdc_100154778664.0x000001

The future of siRNA-mediated approaches to treat von Willebrand disease.

Authors: Linthorst, Noa A., van Vlijmen, Bart J.M, Eikenboom, Jeroen C.J

Source: Expert Review of Hematology; Feb2025, Vol. 18 Issue 2, p109-122, 14p

Impaired adhesion of neutrophils expressing Slc44a2/HNA-3b to VWF protects against NETosis under venous shear rates

Authors: Zirka, Gaïa, Robert, Philippe, Tilburg, Julia, Tishkova, Victoria, Maracle, Chrissta X., Legendre, Paulette, van Vlijmen, Bart J.M., Alessi, Marie-Christine, Lenting, Peter J., Morange, Pierre-Emmanuel, Thomas, Grace M. ^*

Source: In Blood 22 April 2021 137(16):2256-2266

Novel biomarkers to detect occult cancer in patients with unprovoked venous thromboembolism: Rationale and design of the PLATO-VTE study

Authors: Kraaijpoel, Noémie, Mulder, Frits I., Carrier, Marc, van Lieshout, Annabel, Würdinger, Tom, Best, Myron G., van Vlijmen, Bart J.M., Mohammed, Yassene, Jara-Palomares, Luis, Kamphuisen, Pieter W., Di Nisio, Marcello, Ageno, Walter, Beyer-Westendorf, Jan, Vanassche, Thomas, Klokm, Frederikus A., Otten, Hans-Martin, Peters, Mike J.L., Cosmi, Benilde, Wolde, Marije ten, Bossuyt, Patrick M.M., Büller, Harry R., van Es, Nick

Source: In Thrombosis Update 2021 2

SLC44A2 deficient mice have a reduced response in stenosis but not in hypercoagulability driven venous thrombosis

Authors: Tilburg, Julia, Coenen, Daniëlle M., Zirka, Gaia, Dólleman, Sophie, van Oeveren‐Rietdijk, Annemarie M., Karel, Mieke F.A., de Boer, Hetty C., Cosemans, Judith M.E.M., Versteeg, Henri H., Morange, Pierre E., van Vlijmen, Bart J.M. ^*, Maracle, Chrissta X., Thomas, Grace M.

Source: In Journal of Thrombosis and Haemostasis July 2020 18(7):1714-1727

Mouse venous thrombosis upon silencing of anticoagulants depends on tissue factor and platelets, not FXII or neutrophils

Authors: Heestermans, Marco, Salloum-Asfar, Salam, Streef, Tom, Laghmani, El Houari, Salvatori, Daniela, Luken, Brenda M., Zeerleder, Sacha S., Spronk, Henri M.H., Korporaal, Suzanne J., Kirchhofer, Daniel, Wagenaar, Gerry T.M., Versteeg, Henri H., Reitsma, Pieter H., Renné, Thomas, van Vlijmen, Bart J.M. ^*

Source: In Blood 9 May 2019 133(19):2090-2099

Characterization of hemostasis in mice lacking the novel thrombosis susceptibility gene Slc44a2

Authors: Tilburg, Julia, Adili, Reheman, Nair, Thankam S., Hawley, Megan E., Tuk, David C., Jackson, Madeline, Spronk, Henri M., Versteeg, Henri H., Carey, Thomas E., van Vlijmen, Bart J.M., Maracle, Chrissta X., Holinstat, Michael

Source: In Thrombosis Research November 2018 171:155-159

Use of 'C9/11 Mismatch' Control siRNA Reveals Sequence-Related Off-Target Effect on Coagulation of an siRNA Targeting Mouse Coagulation Factor XII

Authors: Heestermans, Marco, de Jong, Annika, van Tilburg, Sander, Reitsma, Pieter H., Versteeg, Henri H., Spronk, Henri M., van Vlijmen, Bart J.M.

Source: Nucleic acid therapeutics. 29(4):218-223

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100086280821.0x000001&indx=1&recIds=ETOCvdc_100086280821.0x000001

Role of platelets, neutrophils, and factor XII in spontaneous venous thrombosis in mice

Authors: Heestermans, Marco, Salloum-Asfar, Salam, Salvatori, Daniela, Laghmani, El Houari, Luken, Brenda M., Zeerleder, Sacha S., Spronk, Henri M.H., Korporaal, Suzanne J., Wagenaar, Gerry T.M., Reitsma, Pieter H., van Vlijmen, Bart J.M. ^*

Source: In Blood 26 May 2016 127(21):2630-2637

Oligonucleotides targeting coagulation factor mRNAs: use in thrombosis and hemophilia research and therapy

Authors: Heestermans, Marco, van Vlijmen, Bart J.M.

Source: Thrombosis journal. 15(1):1-8

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111693425.0x000001&indx=1&recIds=ETOCvdc_100111693425.0x000001

Silencing of Anticoagulant Protein C Evokes Low-Incident but Spontaneous Atherothrombosis in Apolipoprotein E–Deficient Mice—Brief Report

Authors: Ouweneel, Amber B., Heestermans, Marco, Verwilligen, Robin A.F., Gijbels, Marion J.J., Reitsma, Pieter H., Van Eck, Miranda, van Vlijmen, Bart J.M.

Source: Arteriosclerosis, thrombosis, and vascular biology. 37(5):782-785

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100043785677.0x000001&indx=1&recIds=ETOCvdc_100043785677.0x000001

Circulating nucleosomes and elastase α1-antitrypsin complexes and the novel thrombosis susceptibility locus SLC44A2

Authors: Heestermans, Marco, Cunha, Marisa L.R., Reitsma, Pieter H., Zeerleder, Sacha S., Middeldorp, Saskia, van Vlijmen, Bart J.M.

Source: Thrombosis research. 142:8-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100031955741.0x000001&indx=1&recIds=ETOCvdc_100031955741.0x000001

Macrophage p53 controls macrophage death in atherosclerotic lesions of apolipoprotein E deficient mice

Authors: Boesten, Lianne S.M., Zadelaar, A. Susanne M., van Nieuwkoop, Anita, Hu, Lihui, Teunisse, Amina F.A.S., Jochemsen, Aart G., Evers, Bastiaan, van de Water, Bob, Gijbels, Marion J.J., van Vlijmen, Bart J.M., Havekes, Louis M., de Winther, Menno P.J.

Source: In Atherosclerosis 2009 207(2):399-404

The hepatic uptake of VLDL in lrp−ldlr−/−vldlr−/− mice is regulated by LPL activity and involves proteoglycans and SR-BI

Authors: Hu, Lihui ^*, van der Hoogt, Caroline C. ^*, Espirito Santo, Sonia M.S. ^*, Out, Ruud, Kypreos, Kyriakos E. ^**, van Vlijmen, Bart J.M. ^*, Van Berkel, Theo J.C., Romijn, Johannes A., Havekes, Louis M. ^*, van Dijk, Ko Willems, Rensen, Patrick C.N. ^*

Source: In Journal of Lipid Research July 2008 49(7):1553-1561