HCoV-229E Mpro Suppresses RLR-Mediated Innate Immune Signalling Through Cleavage of NEMO and Through Other Mechanisms.

Authors: Martiáñez-Vendrell, Xavier¹ (AUTHOR) x.vendrell@lumc.nl, van Kasteren, Puck B.¹ (AUTHOR), Myeni, Sebenzile K.¹ (AUTHOR), Kikkert, Marjolein¹ (AUTHOR) m.kikkert@lumc.nl

Source: International Journal of Molecular Sciences. Feb2025, Vol. 26 Issue 3, p1197. 24p.

Subject Terms: *PATTERN perception receptors, *INTERFERON gamma, *COMMON cold, *RNA viruses, *IMMUNE response, *CORONAVIRUSES

The role of respiratory syncytial virus G protein in immune cell infection and pathogenesis

Authors: Anderson, Jeremy, Do, Lien Anh Ha, van Kasteren, Puck B., Licciardi, Paul V.

Source: In eBioMedicine September 2024 107

Characterization of SARS-CoV-2 replication in human H1299/ACE2 cells: A versatile and practical infection model for antiviral research and beyond

Authors: Salgado-Benvindo, Clarisse, Tas, Ali, Zevenhoven-Dobbe, Jessika C., van der Meer, Yvonne, Sidorov, Igor A., Leijs, Anouk A., Wanningen, Patrick, Gelderloos, Anne T., van Kasteren, Puck B., Snijder, Eric J., van Hemert, Martijn J.

Source: In Antiviral Research July 2024 227

Development of an inhalable antiviral powder formulation against respiratory syncytial virus

Authors: Heida, Rick, Akkerman, Renate, Jacob Silva, Paulo H., Lakerveld, Anke J., Ortiz, Daniel, Bigogno, Chiara, Gasbarri, Matteo, van Kasteren, Puck B., Stellacci, Francesco, Frijlink, Henderik W., Huckriede, Anke L.W., Hinrichs, Wouter L.J.

Source: Journal of controlled release. 357:264-273

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195222499.0x000001&indx=1&recIds=ETOCvdc_100195222499.0x000001

Decline of RSV-specific antibodies during the COVID-19 pandemic

Authors: den Hartog, Gerco, van Kasteren, Puck B, Schepp, Rutger M, Teirlinck, Anne C, van der Klis, Fiona R M, van Binnendijk, Robert S

Source: Lancet infectious diseases. 23(1):23-25

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178000234.0x000001&indx=1&recIds=ETOCvdc_100178000234.0x000001

Comparison of air-liquid interface transwell and airway organoid models for human respiratory virus infection studies.

Authors: Ekanger, Camilla T., Dinesh Kumar, Nilima, Koutstaal, Rosanne W., Zhou, Fan, Beukema, Martin, Waldock, Joanna, Jochems, Simon P., Mulder, Noa, van Els, Cécile A. C. M., Engelhardt, Othmar G., Mantel, Nathalie, Buno, Kevin P., Brokstad, Karl Albert, Engelsen, Agnete S. T., Cox, Rebecca J., Melgert, Barbro N., Huckriede, Anke L. W., van Kasteren, Puck B.

Source: Frontiers in Immunology; 2025, p1-16, 16p

Subject Terms: VIRUS diseases, AIRWAY (Anatomy), INFLUENZA A virus, RESPIRATORY infections, VIRAL replication

Inno4Vac Workshop Report Part 1: Controlled Human Influenza Virus Infection Model (CHIVIM) Strain Selection and Immune Assays for CHIVIM Studies, November 2021, MHRA, UK.

Authors: Waldock, Joanna, Cox, Rebecca J., Chiu, Christopher, Subbarao, Kanta, Wildfire, Adrian, Barclay, Wendy, van Kasteren, Puck B., McCauley, John, Russell, Colin A., Smith, Derek, Thwaites, Ryan S., Tregoning, John S., Engelhardt, Othmar G.

Source: Influenza & Other Respiratory Viruses; Nov2024, Vol. 18 Issue 11, p1-9, 9p

Subject Terms: RESPIRATORY syncytial virus, VIRUS diseases, INFLUENZA viruses, CLOSTRIDIOIDES difficile, COMMUNICABLE diseases

Comparison of seven commercial RT-PCR diagnostic kits for COVID-19

Authors: van Kasteren, Puck B., van der Veer, Bas, van den Brink, Sharon, Wijsman, Lisa, de Jonge, Jørgen, van den Brandt, Annemarie, Molenkamp, Richard, Reusken, Chantal B.E.M., Meijer, Adam ^*

Source: In Journal of Clinical Virology July 2020 128

Respiratory Syncytial Virus Infects Primary Neonatal and Adult Natural Killer Cells and Affects Their Antiviral Effector Function

Authors: van Erp, Elisabeth A., Feyaerts, Dorien, Duijst, Maxime, Mulder, H. Lie, Wicht, Oliver, Luytjes, Willem, Ferwerda, Gerben, van Kasteren, Puck B.

Source: The Journal of Infectious Diseases, 2019 Mar 01. 219(5), 723-733.

Access URL: https://www.jstor.org/stable/26748987

Repeated COVID-19 mRNA vaccination results in IgG4 class switching and decreased NK cell activation by S1-specific antibodies in older adults.

Authors: Gelderloos, Anne T., Verheul, Marije K., Middelhof, Irene, de Zeeuw-Brouwer, Mary-Lène, van Binnendijk, Robert S., Buisman, Anne-Marie, van Kasteren, Puck B.

Source: Immunity & Ageing; 9/14/2024, Vol. 21 Issue 1, p1-14, 14p

Subject Terms: IMMUNOGLOBULIN class switching, KILLER cells, VACCINE effectiveness, OLDER people, COVID-19 vaccines

Primary SARS‐CoV‐2 infection in children and adults results in similar Fc‐mediated antibody effector function patterns.

Authors: Gelderloos, Anne T, Lakerveld, Anke J, Schepp, Rutger M, Nicolaie, Mioara Alina, van Beek, Josine, Beckers, Lisa, van Binnendijk, Robert S, Rots, Nynke Y, van Kasteren, Puck B

Source: Clinical & Translational Immunology; 2024, Vol. 13 Issue 8, p1-16, 16p

Subject Terms: KILLER cells, IMMUNE response, ANTIBODY formation, MULTIPLE comparisons (Statistics), VIRUS diseases

Prevalence of human respiratory pathogens and associated mucosal cytokine levels in young children and adults: a cross-sectional observational study in the Netherlands during the winter of 2012/2013.

Authors: van Kasteren, Puck B¹ (AUTHOR), Gelderloos, Anne T¹ (AUTHOR), Nicolaie, Mioara Alina¹ (AUTHOR), den Hartog, Gerco¹ (AUTHOR), Vissers, Marloes¹ (AUTHOR), Luytjes, Willem¹ (AUTHOR), Rots, Nynke Y¹ (AUTHOR), van Beek, Josine¹ (AUTHOR)

Source: Pathogens & Disease. 2024, Vol. 82, p1-13. 13p.

Subject Terms: *MEDICAL personnel, *RESPIRATORY syncytial virus, *PREVENTIVE medicine, *MEDICAL care, *PARENTS

Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression

Authors: Bailey-Elkin, Ben A., Knaap, Robert C.M., Johnson, Garrett G., Dalebout, Tim J., Ninaber, Dennis K., van Kasteren, Puck B., Bredenbeek, Peter J., Snijder, Eric J., Kikkert, Marjolein, Mark, Brian L.

Source: In Journal of Biological Chemistry 12 December 2014 289(50):34667-34682

Difference in respiratory syncytial virus-specific Fc-mediated antibody effector functions between children and adults.

Authors: Lakerveld, Anke J, Gelderloos, Anne T, Schepp, Rutger M, de Haan, Cornelis A M, van Binnendijk, Robert S, Rots, Nynke Y, van Beek, Josine, van Els, Cécile A C M, van Kasteren, Puck B

Source: Clinical & Experimental Immunology; Oct2023, Vol. 214 Issue 1, p79-93, 15p, 1 Diagram, 1 Chart, 7 Graphs

Subject Terms: IMMUNE response, RESPIRATORY syncytial virus infections, KILLER cells, PHAGOCYTOSIS, IMMUNOGLOBULINS, RESPIRATORY syncytial virus

Response to letter of concern by Oladimeji and Pickford of PrimerDesign

Authors: van Kasteren, Puck B., van der Veer, Bas, Reusken, Chantal B.E.M., Meijer, Adam

Source: Journal of clinical virology. 129

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116682049.0x000001&indx=1&recIds=ETOCvdc_100116682049.0x000001

Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells

Authors: van Kasteren, Puck B., Bailey-Elkin, Ben A., James, Terrence W., Ninaber, Dennis K., Beugeling, Corrine, Khajehpour, Mazdak, Snijder, Eric J., Mark, Brian L., Kikkert, Marjolein

Source: Proceedings of the National Academy of Sciences of the United States of America, 2013 Feb . 110(9), 3220-3220.

Access URL: https://www.jstor.org/stable/42583574

Rescue and in vitro characterization of a divergent TBEV-Eu strain from the Netherlands.

Authors: Hoornweg, Tabitha E., Godeke, Gert-Jan, Hoogerwerf, Marieke N., van Kasteren, Puck B., de Vries, Ankje, Sprong, Hein, Verjans, Georges M. G. M., van Riel, Debby, Reimerink, Johan H. J., Rockx, Barry, Reusken, Chantal B. E. M.

Source: Scientific Reports; 2/18/2023, Vol. 13 Issue 1, p1-14, 14p

Subject Terms: TYPE I interferons, CENTRAL nervous system infections, TICK-borne encephalitis viruses, TICK-borne encephalitis

Geographic Terms: NETHERLANDS

Pathology and Immunity After SARS-CoV-2 Infection in Male Ferrets Is Affected by Age and Inoculation Route.

Authors: van de Ven, Koen, van Dijken, Harry, Wijsman, Lisa, Gomersbach, Angéla, Schouten, Tanja, Kool, Jolanda, Lenz, Stefanie, Roholl, Paul, Meijer, Adam, van Kasteren, Puck B., de Jonge, Jørgen

Source: Frontiers in Immunology; 10/21/2021, Vol. 12, p1-15, 15p

Subject Terms: SARS-CoV-2, FERRET, VACCINATION, COVID-19, PATHOLOGY, INFECTION, HERD immunity, HUMORAL immunity

Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.

Authors: Zhang, Wei¹, Bailey-Elkin, Ben A.², Knaap, Robert C. M.³, Khare, Baldeep², Dalebout, Tim J.³, Johnson, Garrett G.², van Kasteren, Puck B.³, McLeish, Nigel J.², Gu, Jun¹, He, Wenguang², Kikkert, Marjolein³, m.kikkert@lumc.nl, Mark, Brian L.², brian.mark@umanitoba.ca, Sidhu, Sachdev S.¹, sachdev.sidhu@utoronto.ca

Source: PLoS Pathogens; 5/18/2017, Vol. 13 Issue 5, p1-21, 21p

Viral OTU Deubiquitinases: A Structural and Functional Comparison.

Authors: Bailey-Elkin, Ben A.¹, van Kasteren, Puck B.², Snijder, Eric J.², Kikkert, Marjolein² m.kikkert@lumc.nl, Mark, Brian L.¹ brian_mark@umanitoba.ca

Source: PLoS Pathogens. Mar2014, Vol. 10 Issue 3, p1-6. 6p.

Subject Terms: *PROTEOLYTIC enzymes, *RNA viruses, *OVARIAN tumors, *VIRUS-induced enzymes, *PROTEOLYSIS