Rebalancing of mitochondrial homeostasis through an NAD+-SIRT1 pathway preserves intestinal barrier function in severe malnutrition

Authors: Ling, Catriona, Versloot, Christian J., Arvidsson Kvissberg, Matilda E., Hu, Guanlan, Swain, Nathan, Horcas-Nieto, José M., Miraglia, Emily, Thind, Mehakpreet K., Farooqui, Amber, Gerding, Albert, van Eunen, Karen, Koster, Mirjam H., Kloosterhuis, Niels J., Chi, Lijun, ChenMi, YueYing, Langelaar-Makkinje, Miriam, Bourdon, Celine, Swann, Jonathan, Smit, Marieke, de Bruin, Alain, Youssef, Sameh A., Feenstra, Marjon, van Dijk, Theo H., Thedieck, Kathrin, Jonker, Johan W., Kim, Peter K., Bakker, Barbara M., Bandsma, Robert H.J.

Source: In eBioMedicine October 2023 96

FGF1 and insulin control lipolysis by convergent pathways

Authors: Sancar, Gencer, Liu, Sihao, Gasser, Emanuel, Alvarez, Jacqueline G., Moutos, Christopher, Kim, Kyeongkyu, van Zutphen, Tim, Wang, Yuhao, Huddy, Timothy F., Ross, Brittany, Dai, Yang, Zepeda, David, Collins, Brett, Tilley, Emma, Kolar, Matthew J., Yu, Ruth T., Atkins, Annette R., van Dijk, Theo H., Saghatelian, Alan, Jonker, Johan W., Downes, Michael, Evans, Ronald M.

Source: In Cell Metabolism 4 January 2022 34(1):171-183

Increased insulin sensitivity and diminished pancreatic beta-cell function in DNA repair deficient Ercc1d/− mice

Authors: Huerta Guevara, Ana P., McGowan, Sara J., Kazantzis, Melissa, Stallons, Tania Rozgaja, Sano, Tokio, Mulder, Niels L., Jurdzinski, Angelika, van Dijk, Theo H., Eggen, Bart J.L., Jonker, Johan W., Niedernhofer, Laura J., Kruit, Janine K.

Source: In Metabolism April 2021 117

Effect of mulberry fruit extract on glucose fluxes after a wheat porridge meal: a dual isotope study in healthy human subjects.

Authors: Boers, Hanny M.¹ (AUTHOR) hanny.boers@unilever.com, van Dijk, Theo H.² (AUTHOR), Duchateau, Guus S.¹ (AUTHOR), Mela, David J.¹ (AUTHOR) djmela@djmela.eu, Hiemstra, Harry¹ (AUTHOR), Hoogenraad, Anne-Roos¹ (AUTHOR), Priebe, Marion G.³ (AUTHOR)

Source: European Journal of Clinical Nutrition. Jul2023, Vol. 77 Issue 7, p741-747. 7p.

Short‐term protein restriction at advanced age stimulates FGF21 signalling, energy expenditure and browning of white adipose tissue

Authors: Dommerholt, Marleen B., Blankestijn, Maaike, Vieira‐Lara, Marcel A., van Dijk, Theo H., Wolters, Henk, Koster, Mirjam H., Gerding, Albert, van Os, Ronald P., Bloks, Vincent W., Bakker, Barbara M., Kruit, Janine K., Jonker, Johan W.

Source: FEBS journal. 288(7):2257-2277

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121208431.0x000001&indx=1&recIds=ETOCvdc_100121208431.0x000001

Efficient reabsorption of transintestinally excreted cholesterol is a strong determinant for cholesterol disposal in mice

Authors: van de Peppel, Ivo P. ^*, Bertolini, Anna ^*, van Dijk, Theo H. ^†, Groen, Albert K. ^{*, §}, Jonker, Johan W. ^*, Verkade, Henkjan J. ^*

Source: In Journal of Lipid Research September 2019 60(9):1562-1572

FXR overexpression alters adipose tissue architecture in mice and limits its storage capacity leading to metabolic derangements

Authors: van Zutphen, Tim ^{*, †}, Stroeve, Johanna H.M. ^*, Yang, Jiufang ^*, Bloks, Vincent W. ^*, Jurdzinski, Angelika ^*, Roelofsen, Han ^§, Huijkman, Nicolette C.A. ^*, van Dijk, Theo H. ^{*, **}, Vonk, Roel J. ^§, van Deursen, Jan ^††, Staels, Bart ^§§, Groen, Albert K. ^{*, **, ***}, Kuipers, Folkert ^{*, **}

Source: In Journal of Lipid Research September 2019 60(9):1547-1561

Intestinal Farnesoid X Receptor Modulates Duodenal Surface Area but Does Not Control Glucose Absorption in Mice.

Authors: Yang, Jiufang¹ (AUTHOR), van Dijk, Theo H.¹ (AUTHOR), Koehorst, Martijn² (AUTHOR), Havinga, Rick¹ (AUTHOR), de Boer, Jan Freark¹ (AUTHOR), Kuipers, Folkert^1,2,3 (AUTHOR) f.kuipers@umcg.nl, van Zutphen, Tim^1,4 (AUTHOR) f.kuipers@umcg.nl

Source: International Journal of Molecular Sciences. Feb2023, Vol. 24 Issue 4, p4132. 19p.

Subject Terms: *FARNESOID X receptor, *GLUCOSE, *SURFACE area, *INTESTINES, *MICE, *INTESTINAL absorption

Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice

Authors: de Boer, Jan Freark, Schonewille, Marleen, Boesjes, Marije, Wolters, Henk, Bloks, Vincent W., Bos, Trijnie, van Dijk, Theo H., Jurdzinski, Angelika, Boverhof, Renze, Wolters, Justina C., Kuivenhoven, Jan A., van Deursen, Jan M., Oude Elferink, Ronald P.J., Moschetta, Antonio, Kremoser, Claus, Verkade, Henkjan J., Kuipers, Folkert, Groen, Albert K.

Source: In Gastroenterology April 2017 152(5):1126-1138

Transintestinal Cholesterol Transport Is Active in Mice and Humans and Controls Ezetimibe-Induced Fecal Neutral Sterol Excretion

Authors: Jakulj, Lily, van Dijk, Theo H., de Boer, Jan Freark, Kootte, Ruud S., Schonewille, Marleen, Paalvast, Yared, Boer, Theo, Bloks, Vincent W., Boverhof, Renze, Nieuwdorp, Max, Beuers, Ulrich H.W., Stroes, Erik S.G., Groen, Albert K.

Source: In Cell Metabolism 13 December 2016 24(6):783-794

VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications

Authors: Robciuc, Marius R., Kivelä, Riikka, Williams, Ian M., de Boer, Jan Freark, van Dijk, Theo H., Elamaa, Harri, Tigistu-Sahle, Feven, Molotkov, Dmitry, Leppänen, Veli-Matti, Käkelä, Reijo, Eklund, Lauri, Wasserman, David H., Groen, Albert K., Alitalo, Kari

Source: In Cell Metabolism 12 April 2016 23(4):712-724

Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4

Authors: Out, Carolien, Patankar, Jay V., Doktorova, Marcela, Boesjes, Marije, Bos, Trijnie, de Boer, Sanna, Havinga, Rick, Wolters, Henk, Boverhof, Renze, van Dijk, Theo H., Smoczek, Anna, Bleich, André, Sachdev, Vinay, Kratky, Dagmar, Kuipers, Folkert, Verkade, Henkjan J., Groen, Albert K.

Source: In Journal of Hepatology September 2015 63(3):697-704

Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA

Authors: Kootte, Ruud S. ^*, Smits, Loek P. ^*, van der Valk, Fleur M. ^*, Dasseux, Jean-Louis ^†, Keyserling, Constance H. ^†, Barbaras, Ronald ^†, Paolini, John F. ^†, Santos, Raul D. ^§, van Dijk, Theo H. ^**, Dallinga-van Thie, Geesje M. ^*, Nederveen, Aart J. ^††, Mulder, WillemJ.M. ^*, Hovingh, G.Kees ^*, Kastelein, JohnJ.P. ^*, Groen, Albert K. ^**, Stroes, ErikS. ^*

Source: In Journal of Lipid Research March 2015 56(3):703-712

Endogenous Glucose Production in Patients With Glycogen Storage Disease Type Ia Estimated by Oral D-[6,6-2H2]-glucose

Authors: Rossi, Alessandro, Oosterveer, Maaike H, van Dijk, Theo H, Bleeker, Aycha, Koehorst, Martijn, Weinstein, David A, Bakker, Barbara M, Derks, Terry G J

Source: The Journal of Clinical Endocrinology & Metabolism; February 2024, Vol. 109 Issue: 2 p389-401, 13p

Lactate increases hepatic secretion of VLDL-triglycerides in humans

Authors: Sondermeijer, Brigitte M., Battjes, Suzanne, van Dijk, Theo H., Ackermans, Mariëtte T., Serlie, Mireille J., Nieuwdorp, Max, Groen, Albert K., Dallinga-Thie, Geesje M., Stroes, Erik S.G.

Source: In Atherosclerosis June 2013 228(2):443-450

Plasma plant sterols serve as poor markers of cholesterol absorption in man

Authors: Jakulj, Lily ^*, Mohammed, Hussein ^†, van Dijk, Theo H. ^{§, **}, Boer, Theo ^**, Turner, Scott ^†, Groen, Albert K. ^{§, **}, Vissers, Maud N. ^*, Stroes, Erik S.G. ^*

Source: In Journal of Lipid Research April 2013 54(4):1144-1150

Bile Acid Sequestration via Colesevelam Reduces Bile Acid Hydrophobicity and Improves Liver Pathology in Cyp2c70 −/− Mice with a Human-like Bile Acid Composition.

Authors: Palmiotti, Anna, de Vries, Hilde D., Hovingh, Milaine V., Koehorst, Martijn, Mulder, Niels L., Verkade, Esther, Veentjer, Melany K., van Dijk, Theo H., Bloks, Vincent W., Havinga, Rick, Verkade, Henkjan J., de Boer, Jan Freark, Kuipers, Folkert

Source: Biomedicines; Sep2023, Vol. 11 Issue 9, p2495, 15p

Subject Terms: BILE acids, HEPATIC fibrosis, MICE, LIVER, INSULIN sensitivity

Age and Diet Modulate the Insulin-Sensitizing Effects of Exercise: A Tracer-Based Oral Glucose Tolerance Test.

Authors: Vieira-Lara, Marcel A., Reijne, Aaffien C., Koshian, Serj, Ciapaite, Jolita, Abegaz, Fentaw, Talarovicova, Alzbeta, van Dijk, Theo H., Versloot, Christian J., Bandsma, Robert H.J., Wolters, Justina C., Groen, Albert K., Reijngoud, Dirk-Jan, van Dijk, Gertjan, Bakker, Barbara M.

Source: Diabetes; Jul2023, Vol. 72 Issue 7, p872-883, 12p

Subject Terms: GLUCOSE tolerance tests, HIGH-fat diet, LOW-fat diet, DIET, INSULIN sensitivity

Kwashiorkor and marasmus are both associated with impaired glucose clearance related to pancreatic β-cell dysfunction

Authors: Spoelstra, Martijn N., Mari, Andrea, Mendel, Marijke, Senga, Edward, van Rheenen, Patrick, van Dijk, Theo H., Reijngoud, Dirk-Jan, Zegers, Remco G.T., Heikens, Geert Tom, Bandsma, Robert H.J.

Source: In Metabolism September 2012 61(9):1224-1230

Sex-Dependent Programming of Glucose and Fatty Acid Metabolism in Mouse Offspring by Maternal Protein Restriction

Authors: van Straten, Esther M.E., Bloks, Vincent W., van Dijk, Theo H., Baller, Julius F.W., Huijkman, Nicolette C.A., Kuipers, Irma, Verkade, Henkjan J., Plösch, Torsten

Source: In Gender Medicine June 2012 9(3):166-179