Dynamic Prediction of Advanced Colorectal Neoplasia in Inflammatory Bowel Disease

Authors: van Bodegraven, Adriaan A., Fidder, Herma H., Hirdes, Meike M.C., Hoentjen, Frank, Jansen, Jeroen M., Mahmmod, Nofel, van der Meulen-de Jong, Andrea E., Ponsioen, Cyriel Y., van Schaik, Fiona D.M., van der Woude, C. Janneke, Wijnands, Anouk M., Penning de Vries, Bas B.L., Lutgens, Maurice W.M.D., Bakhshi, Zeinab, Al Bakir, Ibrahim, Beaugerie, Laurent, Bernstein, Charles N., Chang-ho Choi, Ryan, Coelho-Prabhu, Nayantara, Graham, Trevor A., Hart, Ailsa L., ten Hove, Joren R., Itzkowitz, Steven H., Kirchgesner, Julien, Mooiweer, Erik, Shaffer, Seth R., Shah, Shailja C., Elias, Sjoerd G., Oldenburg, Bas

Source: In Clinical Gastroenterology and Hepatology August 2024 22(8):1697-1708

Increased versus conventional adalimumab dose interval for patients with Crohn's disease in stable remission (LADI): a pragmatic, open-label, non-inferiority, randomised controlled trial

Authors: van Noord, Desirée, Hoekstra, Jildou, Kamphuis, Johannes T., Gorter, Moniek H.P., van Esch, Aura A.J., van Linschoten, Reinier C A ^*, Jansen, Fenna M ^*, Pauwels, Renske W M, Smits, Lisa J T, Atsma, Femke, Kievit, Wietske, de Jong, Dirk J, de Vries, Annemarie C, Boekema, Paul J, West, Rachel L, Bodelier, Alexander G L, Gisbertz, Ingrid A M, Wolfhagen, Frank H J, Römkens, Tessa E H, Lutgens, Maurice W M D, van Bodegraven, Adriaan A, Oldenburg, Bas, Pierik, Marieke J, Russel, Maurice G V M, de Boer, Nanne K, Mallant-Hent, Rosalie C, ter Borg, Pieter C J, van der Meulen-de Jong, Andrea E, Jansen, Jeroen M, Jansen, Sita V, Tan, Adrianus C I T L, van der Woude, C Janneke, Hoentjen, Frank ^*

Source: In The Lancet Gastroenterology & Hepatology April 2023 8(4):343-355

Superior Effectiveness of Tofacitinib Compared to Vedolizumab in Anti-TNF-experienced Ulcerative Colitis Patients: A Nationwide Dutch Registry Study

Authors: Schlotter, Malena, van Workum, Martine, de Jong, Dirk, van Dop, Willemijn, van der Marel, S., El Ghabzouri, Hayat, Talhaoui, Kamila, Oldenburg, Bas, Boontje, Nynke, Fidder, Herma, Hirdes, Meike, Creemers, Rob H., Hoekstra, J., Smid, Jael, Mujagic, Zlatan, François-Verweij, Marthe, Schakel- van den Berge, Toos, Maljaars, Jeroen, Theeuwen, Rosaline, van den Berg, Denise, Gerretsen, Suzanne, Yocarini, Xenia, D’Haens, Geert, Lowenberg, Mark, Grootjans, Joep, Gecse, Krisztina, Bouma, Gerd, Waaijenberg, Petra, Muskens, Bart, Straatmijer, Tessa, Biemans, Vince B.C., Visschedijk, Marijn, Hoentjen, Frank, de Vries, Annemarie, van Bodegraven, Adriaan A., Bodelier, Alexander, de Boer, Nanne K.H., Dijkstra, Gerard, Festen, Noortje, Horjus, Carmen, Jansen, Jeroen M., Jharap, Bindia, Mares, Wout, van Schaik, Fiona D.M., Ponsioen, Cyriel, Romkens, Tessa, Srivastava, Nidhi, van der Voorn, Michael M.P. J.A., West, Rachel, van der Woude, Janneke, Wolvers, Marije D.J., Pierik, Marieke, van der Meulen-de Jong, Andrea E., Duijvestein, Marjolijn

Source: In Clinical Gastroenterology and Hepatology January 2023 21(1):182-191

Predictive Algorithm for Thiopurine-Induced Hepatotoxicity in Inflammatory Bowel Disease Patients

Authors: van Moorsel, Sofia A. W., Deben, Debbie S., Creemers, Rob H., Winkens, Bjorn, Bus, Paul, Pierik, Marieke J., Simsek, Melek, de Boer, Nanne K. H., van Bodegraven, Adriaan A., Wong, Dennis R.

Source: Therapeutic drug monitoring. 44(6):747-754

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178786899.0x000001&indx=1&recIds=ETOCvdc_100178786899.0x000001

Classic drugs in the time of new drugs: real‐world, long‐term outcomes of thiopurine monotherapy in 1016 patients with inflammatory bowel disease

Authors: Rezazadeh Ardabili, Ashkan, Jeuring, Steven, Mujagic, Zlatan, Oostenbrug, Liekele, Romberg‐Camps, Mariëlle, Jonkers, Daisy, van Bodegraven, Adriaan, Pierik, Marieke

Source: Alimentary pharmacology & therapeutics. 56(6):1030-1043

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100158946924.0x000001&indx=1&recIds=ETOCvdc_100158946924.0x000001

Effects of processed meat and drinking water nitrate on oral and fecal microbial populations in a controlled feeding study

Authors: Sinha, Rashmi, Zhao, Ni, Goedert, James J., Byrd, Doratha A., Wan, Yunhu, Hua, Xing, Hullings, Autumn G., Knight, Rob, Breda, Simone van, Mathijs, Karen, de Kok, Theo M., Ward, Mary H., Pieters, Harm-Jan, Sági-Kiss, Virág, Kuhnle, Gunter G., Georgiadis, Panagiotis, Saccani, Giovanna, Parolari, Giovanni, Virgili, Roberta, Hemke, Gert, Hung, Yung, Verbeke, Wim, Masclee, Ad A., Vleugels-Simon, Carla B., van Bodegraven, Adriaan A., Dobbelaere, Dirk, Vandewynkel, Anneleen, Kruijk, Richard van der, Egberts, Frans, Helvoirt, Jan-Hein van

Source: In Environmental Research June 2021 197

Current status and future perspectives on the use of therapeutic drug monitoring of thiopurine metabolites in patients with inflammatory bowel disease

Authors: Deben, Debbie S., Wong, Dennis R., van Bodegraven, Adriaan A.

Source: Expert opinion on drug metabolism and toxicology. 17(12):1433-1444

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141709881.0x000001&indx=1&recIds=ETOCvdc_100141709881.0x000001

Early therapeutic drug monitoring helps to identify inflammatory bowel disease patients with a high risk to fail thiopurine treatment.

Authors: Deben, Debbie S., Winkens, Bjorn, van Moorsel, Sofia A. W., van Oijen, Brigit P. C., Bus, Paul, Pierik, Marieke J., Simsek, Melek, de Boer, Nanne K. H., Leers, Mathie P. G., Wong, Dennis R., van Bodegraven, Adriaan A.

Source: British Journal of Clinical Pharmacology; Dec2024, Vol. 90 Issue 12, p3296-3307, 12p

Subject Terms: INFLAMMATORY bowel diseases, DRUG monitoring, DRUG side effects, TERMINATION of treatment, BODY mass index, AZATHIOPRINE

Identification of spontaneous patient‐reported complaints related to perianal fistula in patients with Crohn's disease.

Authors: Bootsma, Lars, Vollebregt, Paul F., van Bodegraven, Adriaan A., van der Horst, Danielle, Han‐Geurts, Ingrid J. M., Felt‐Bersma, Richelle J. F.

Source: Colorectal Disease; Dec2024, Vol. 26 Issue 12, p2057-2068, 12p

Subject Terms: CROHN'S disease, PATIENT reported outcome measures, OLDER patients, SEXUAL intercourse, PSYCHOLOGICAL factors

Superior Effectiveness of Tofacitinib Compared to Vedolizumab in Anti-TNF-experienced Ulcerative Colitis Patients: A Nationwide Dutch Registry Study

Authors: Straatmijer, Tessa, Biemans, Vince B.C., Visschedijk, Marijn, Hoentjen, Frank, de Vries, Annemarie, van Bodegraven, Adriaan A., Bodelier, Alexander, de Boer, Nanne K.H., Dijkstra, Gerard, Festen, Noortje, Horjus, Carmen, Jansen, Jeroen M., Jharap, Bindia, Mares, Wout, van Schaik, Fiona D.M., Ponsioen, Cyriel, Romkens, Tessa, Srivastava, Nidhi, van der Voorn, Michael M.P. J.A., West, Rachel, van der Woude, Janneke, Wolvers, Marije D.J., Pierik, Marieke, van der Meulen-de Jong, Andrea E., Duijvestein, Marjolijn

Source: Clinical gastroenterology and hepatology. 21(1):182-191.e2

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100177913486.0x000001&indx=1&recIds=ETOCvdc_100177913486.0x000001

Bone loss in patients with inflammatory bowel disease: cause, detection and treatment

Authors: Bravenboer, Nathalie, Oostlander, Angela E., van Bodegraven, Adriaan A.

Source: Current opinion in gastroenterology. 37(2):128-134

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100115231052.0x000001&indx=1&recIds=ETOCvdc_100115231052.0x000001

Clinical Outcomes of Covid-19 in Patients With Inflammatory Bowel Disease: A Nationwide Cohort Study

Authors: Derikx, Lauranne A A P, Lantinga, Marten A, de Jong, Dirk J, van Dop, Willemijn A, Creemers, Rob H, Römkens, Tessa E H, Jansen, Jeroen M, Mahmmod, Nofel, West, Rachel L, Tan, Adriaan C I T L, Bodelier, Alexander G L, Gorter, Moniek H P, Boekema, Paul J, Halet, Eric R C, Horjus, Carmen S, van Dijk, Maarten A, Hirdes, Meike M C, Epping Stippel, Ludger S M, Jharap, Bindia, Lutgens, Maurice W M D, Russel, Maurice G, Gilissen, Lennard P L, Nauta, Sjoukje, van Bodegraven, Adriaan A, Hoentjen, Frank

Source: Journal of Crohn's and colitis. 15(4):529-539

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165587412.0x000001&indx=1&recIds=ETOCvdc_100165587412.0x000001

Finding hidden treasures in old drugs: the challenges and importance of licensing generics

Authors: Simsek, Melek, Meijer, Berrie, van Bodegraven, Adriaan A., de Boer, Nanne K.H., Mulder, Chris J.J.

Source: In Drug Discovery Today January 2018 23(1):17-21

Editorial: IBD cost evolution – transitioning from compensating lost productivity to escalating medication expenses

Authors: Rezazadeh Ardabili, Ashkan, Van Bodegraven, Adriaan A.

Source: Alimentary pharmacology & therapeutics. 58(8):832-833

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194537849.0x000001&indx=1&recIds=ETOCvdc_100194537849.0x000001

Key insights from therapeutic drug monitoring in Crohn's disease patients

Authors: Seinen, Margien L., De Boer, Nanne K., van Bodegraven, Adriaan A.

Source: Expert opinion on drug metabolism and toxicology. 15(5):399-406

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099078341.0x000001&indx=1&recIds=ETOCvdc_100099078341.0x000001

Limited relevance and progression of histological alterations in the liver during thioguanine therapy in inflammatory bowel disease patients

Authors: van Asseldonk, Dirk P., Simsek, Melek, de Boer, Nanne K. H., Jharap, Bindia, Bloemena, Elisabeth, den Hartog, Gijsbert, Westerveld, Dik B., Becx, Marco C., Russel, Maurice G., Lissenberg-Witte, Birgit I., van Nieuwkerk, Carin M., Mulder, Chris J. J., Verheij, Joanne, van Bodegraven, Adriaan A.

Source: Scandinavian journal of gastroenterology. 54(6):753-760

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087551055.0x000001&indx=1&recIds=ETOCvdc_100087551055.0x000001

Sustained effectiveness, safety and therapeutic drug monitoring of tioguanine in a cohort of 274 IBD patients intolerant for conventional therapies

Authors: Simsek, Melek, Deben, Debbie S., Horjus, Carmen S., Bénard, Melanie V., Lissenberg‐Witte, Birgit I., Buiter, Hans J. C., van Luin, Matthijs, Seinen, Margien L., Mulder, Chris J. J., Wong, Dennis R., de Boer, Nanne K. H., van Bodegraven, Adriaan A.

Source: Alimentary pharmacology & therapeutics. 50(1):54-65

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083979887.0x000001&indx=1&recIds=ETOCvdc_100083979887.0x000001

The effect of surgical fecal stream diversion of the healthy colon on the colonic microbiota

Authors: van der Sluis, Wouter B., Bouman, Mark-Bram, Mullender, Margriet G., Degen, Malieka C., Savelkoul, Paul H.M., Meijerink, Wilhelmus J.H.J., de Boer, Nanne K.H., van Bodegraven, Adriaan A., Budding, Andries E.

Source: European journal of gastroenterology & hepatology. 31(4):451-457

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100078349655.0x000001&indx=1&recIds=ETOCvdc_100078349655.0x000001

A Prediction Model for Successful Increase of Adalimumab Dose Intervals in Patients with Crohn's Disease: Secondary Analysis of the Pragmatic Open-Label Randomised Controlled Non-inferiority LADI Trial.

Authors: van Linschoten, Reinier C. A., Jansen, Fenna M., Pauwels, Renske W. M., Smits, Lisa J. T., Atsma, Femke, Kievit, Wietske, de Jong, Dirk J., de Vries, Annemarie C., Boekema, Paul J., West, Rachel L., Bodelier, Alexander G. L., Gisbertz, Ingrid A. M., Wolfhagen, Frank H. J., Römkens, Tessa E. H., Lutgens, Maurice W. M. D., van Bodegraven, Adriaan A., Oldenburg, Bas, Pierik, Marieke J., Russel, Maurice G. V. M., de Boer, Nanne K.

Source: Digestive Diseases & Sciences; Jun2024, Vol. 69 Issue 6, p2165-2174, 10p

Subject Terms: CROHN'S disease, PREDICTION models, SECONDARY analysis, ADALIMUMAB, INTESTINAL diseases, ENTEROSCOPY

Exploring the role of oxidative stress and the effect of N‐acetylcysteine in thiopurine‐induced liver injury in inflammatory bowel disease: A randomized crossover pilot study.

Authors: van Asseldonk, Dirk P., Crouwel, Femke, Seinen, Margien L., Scheffer, Peter G., Veldkamp, Agnes I., de Boer, Nanne K., Lissenberg‐Witte, Birgit, Peters, Godefridus J., van Bodegraven, Adriaan A.

Source: Basic & Clinical Pharmacology & Toxicology; Apr2024, Vol. 134 Issue 4, p507-518, 12p

Subject Terms: INFLAMMATORY bowel diseases, OXIDATIVE stress, LIVER injuries, ACETYLCYSTEINE, XANTHINE oxidase, AMINE oxidase