Head and neck tumor organoid biobank for modelling individual responses to radiation therapy according to the TP53/HPV status

Authors: Christian Issing, Constantin Menche, Mara Romero Richter, Mohammed H. Mosa, Jens von der Grün, Maximilian Fleischmann, Philipp Thoenissen, Ria Winkelmann, Tahmineh Darvishi, Andreas G. Loth, Shahram Ghanaati, Franz Rödel, Peter J. Wild, Christian H. Brandts, Timo Stöver, Henner F. Farin

Source: Journal of Experimental & Clinical Cancer Research, Vol 44, Iss 1, Pp 1-18 (2025)

Subject Terms: Head and neck squamous cell carcinoma, Tumor organoid biobank, Preclinical model, In vitro therapy testing, Radioresistance, Genetic editing, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/13be7930db314c46b6d28d1841f82f37

Significance of mouse xenograft tumor model using patient-derived cancer organoids for clinical drug development

Authors: Hisataka Ogawa, Keiichi Yoshida, Shinichiro Hasegawa, Hiroshi Wada, Masayoshi Yasui, Hideaki Tahara

Source: Frontiers in Oncology, Vol 15 (2025)

Subject Terms: bile duct cancer, tumor organoid, drug screening, cell-line derived xenograft tumor model, organoid-derived xenograft tumor model, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: https://www.frontiersin.org/articles/10.3389/fonc.2025.1485886/full; https://doaj.org/toc/2234-943X

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Evolution of research models for malignant head and neck tumors

Authors: WANG Anxun, ZHOU Wanhang, CAO Congyuan

Source: 口腔疾病防治, Vol 32, Iss 9, Pp 653-663 (2024)

Subject Terms: malignancy, research model, 3d cultivation technology, tumor organoid culture, animal model, cell line derived xenograft, patient-derived xenograft, genetic testing, bioinformatics, digital oncology, intelligent oncology, Medicine

File Description: electronic resource

Relation: https://www.kqjbfz.com/fileup/2096-1456/PDF/2096-1456（2024）09-0653-11.pdf; https://doaj.org/toc/2096-1456

Access URL: https://doaj.org/article/be2ed146fff3431e84f189803a09880e

Preclinical translational research and application of tumor organoids

Authors: XIA Yujia, YANG Zhenli, LIU Yuqin

Source: Jichu yixue yu linchuang, Vol 44, Iss 9, Pp 1214-1218 (2024)

Subject Terms: tumor organoid, precise treatment, organoid biobank, Medicine

File Description: electronic resource

Relation: http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2024-44-9-1214.pdf; https://doaj.org/toc/1001-6325

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Deriving New Ideas for the Diagnosis and Treatment of Pancreatic Neuroendocrine Neoplasms from Basic Research

Authors: WANG Xianze, PING Lu, WU Wenming

Source: Xiehe Yixue Zazhi, Vol 15, Iss 4, Pp 734-739 (2024)

Subject Terms: pancreatic neuroendocrine neoplasm, precision medicine, tumor organoid, liquid biopsy, radiomics, immunotherapy, Medicine

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Relation: https://doaj.org/toc/1674-9081

Access URL: https://doaj.org/article/7ee3a6b22a9447cbab75fea62f7f3aaf

Spatial distribution and activation changes of T cells in pancreatic tumors according to KRAS mutation subtype

Authors: Jeong, Ji Hye ^{a, b, 1}, Shin, Dakyum ^{c, 1}, Kim, Sang-Yeob ^b, Bae, Dong-Jun ^d, Sung, Young Hoon ^{b, e}, Koh, Eun-Young ^{a, b}, Kim, Jinju ^b, Kim, Chong Jai ^f, Park, Jae Soon ^{g, h}, Choi, Jung Kyoon ^{g, h, ⁎}, Kim, Song Cheol ^{i, j, ⁎⁎}, Jun, Eunsung ^{a, b, f, i, ⁎⁎⁎}

Source: In Cancer Letters 28 May 2025 618

Facilitation of Tumor Stroma-Targeted Therapy: Model Difficulty and Co-Culture Organoid Method

Authors: Qiu-Shi Feng, Xiao-Feng Shan, Vicky Yau, Zhi-Gang Cai, Shang Xie

Source: Pharmaceuticals, Vol 18, Iss 1, p 62 (2025)

Subject Terms: stroma mimicry model, patient-derived tumor organoid, co-culture, stroma-related cell, stroma-targeted therapy, Medicine, Pharmacy and materia medica, RS1-441

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Relation: https://www.mdpi.com/1424-8247/18/1/62; https://doaj.org/toc/1424-8247

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Application status and optimization suggestions of tumor organoids and CAR-T cell co-culture models

Authors: Rong-Xuan Ning, Cun-Yu Liu, Shi-Qi Wang, Wen-Kai Li, Xia Kong, Zhi-Wei He

Source: Cancer Cell International, Vol 24, Iss 1, Pp 1-10 (2024)

Subject Terms: Tumor organoid, CAR-T therapy, Co-culture models, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

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Relation: https://doaj.org/toc/1475-2867

Access URL: https://doaj.org/article/08eccc812de0434c964aa529148a4c9c

Tumor-Specific CircRNA-Derived Antigen Peptide Identification for Hepatobiliary Tumors

Authors: Wenwen Wang, Lili Ma, Zheng Xing, Tinggan Yuan, Jinxia Bao, Yanjing Zhu, Xiaofang Zhao, Yan Zhao, Yali Zong, Yani Zhang, Siyun Shen, Xinyao Qiu, Shuai Yang, Hongyang Wang, Dong Gao, Peng Wang, Lei Chen

Source: Engineering, Vol 22, Iss , Pp 159-170 (2023)

Subject Terms: Tumor antigen, Patient-derived hepatobiliary tumor organoid, Circular RNA, Mass-spectrometry-based immunopeptidomics, Engineering (General). Civil engineering (General), TA1-2040

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2095809922004921; https://doaj.org/toc/2095-8099

Access URL: https://doaj.org/article/97991bc036094c10bdd557b331b2e273

A Convexity-Preserving Level-Set Method for the Segmentation of Tumor Organoids

Authors: Xiaoyi Lei, Luying Gui, Hairong Liu

Source: Bioengineering, Vol 11, Iss 6, p 601 (2024)

Subject Terms: convexity, image segmentation, tumor organoid, level set, Technology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2306-5354/11/6/601; https://doaj.org/toc/2306-5354

Access URL: https://doaj.org/article/d9d07a2df5c04510b0b1dc86195288d4

In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application

Contributors: Baiocchi, Marta, Zeuner, Ann

Subject Terms: colorectal cancer, organoids, 3D bioprinting, patient-derived xenograft, cancer-on-chip, drug combination, cancer stem cells, drug resistance, clinical trials, tumor-initiating cells, tumor heterogeneity, patient-derived cancer models, single-cell RNA-sequencing, tumor metabolism, transcriptional programs, tumor cell differentiation, immunotherapy, methods, chromosomal instability, DNA damage, targeted therapy, decitabine, colon cancer, DNA methylation, clinical translation study, machine learning, patient-derived tumor organoid, precision medicine, radiation response, rectal cancer, PDX model, CRC, mutation analysis, histological examination, animal models, in vitro culture, cancer stem cell methods, SATB2, colorectal carcinoma, prognosis, CDX2, circulating tumor cells, CTC cluster, size-based method, ScreenCell®, epithelial mesenchymal transition, hypoxia, HIF-1α, immunofluorescence analysis, sequential filtration, Research and information: general, Biology, life sciences, Microbiology (non-medical)

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Access URL: https://directory.doabooks.org/handle/20.500.12854/91229
https://mdpi.com/books/pdfview/book/5875

Review on Advanced Cancer Modeling for a Cancer Study

Authors: Yong-Hee Cho

Source: Current Issues in Molecular Biology, Vol 44, Iss 11, Pp 5352-5362 (2022)

Subject Terms: organoid, cancer organoid, patient-derived tumor organoid, drug screening, patient-derived tumor xenograft, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/44/11/362; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/255f40c8c5f74fb5b5745a0251141480

Flourishing tumor organoids: History, emerging technology, and application

Authors: Qian Yang, Mengmeng Li, Xinming Yang, Zian Xiao, Xinying Tong, Ayinuer Tuerdi, Shisheng Li, Lanjie Lei

Source: Bioengineering & Translational Medicine, Vol 8, Iss 5, Pp n/a-n/a (2023)

Subject Terms: CRISPR‐Cas9, drug screening, precision medicine, three‐dimensional culture, tumor organoid, Chemical engineering, TP155-156, Biotechnology, TP248.13-248.65, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2380-6761

Access URL: https://doaj.org/article/3cd5adf8e4bd4b258553208a0334117c

Establishment and optimization of air-liquid interface method cultured mouse-derived tumor organoids

Authors: LI Zhao-xuan, LUO Yun-ping, CHEN Chong

Source: Jichu yixue yu linchuang, Vol 42, Iss 5, Pp 782-787 (2022)

Subject Terms: air-liquid interaction method, tumor organoid, immune microenvironment, immune cells, interleukin-2 (il-2), Medicine

File Description: electronic resource

Relation: http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-5-782.pdf; https://doaj.org/toc/1001-6325

Access URL: https://doaj.org/article/a0926211564a4d61863bcbf93c1d5879

Identification of IRAK1BP1 as a candidate prognostic factor in lung adenocarcinoma

Authors: Lei Guo, Weiping Zhou, Ziwei Xu, Xiaoqing Cao, Shiya Wan, Ying Yi Zhang, Jie Zhang, Hezhe Lu

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: lung adenocarcinoma, LUAD, tumor organoid, biomarker, RNA-sequencing, DEG analysis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1132811/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/9812425b2e8b41ef8476188ede779aa0

Repurposing Metabolic Inhibitors in the Treatment of Colon Adenocarcinoma Patient-Derived Models

Authors: Bora Lee, ChuHee Lee, Hae-Min Moon, Se-Young Jo, Se Jin Jang, Young-Ah Suh

Source: Cells, Vol 12, Iss 24, p 2859 (2023)

Subject Terms: cancer metabolism, biguanide, colon tumor, tumor organoid, patient-derived xenograft, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/12/24/2859; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/4659c0894d9d40158f50f51a3cb7d9fe

Screening of an individualized treatment strategy for an advanced gallbladder cancer using patient-derived tumor xenograft and organoid models

Authors: Dengxu Tan, Jiaze An, Miaomiao Gong, Huihui Wang, Han Li, Han Meng, Caiqin Zhang, Yong Zhao, Xu Ge, Changhong Shi

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: gallbladder cancer, patient-derived tumor xenograft model, patient-derived tumor organoid model, individualized therapy, immune checkpoint inhibitors, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.1043479/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/505fc24f27d14857a6e8b1a3d49a0f22

3-Dimensional Model to Study Apoptosis Induction of Activated Natural Killer Cells Conditioned Medium Using Patient-Derived Colorectal Cancer Organoids

Authors: Benyamin Parseh, Ayyoob Khosravi, Abdolreza Fazel, Jafar Ai, Somayeh Ebrahimi-Barough, Javad Verdi, Majid Shahbazi

Source: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Subject Terms: tumor organoid, colon cancer, apoptosis, NK cells, conditioned medium, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2022.895284/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/3e0a0846965b44b29df0a3de37bb6e68

Patient-Derived Tumor Organoids: New Progress and Opportunities to Facilitate Precision Cancer Immunotherapy

Authors: Ji Wang, Chao Chen, Lu Wang, Mingjun Xie, Xinyang Ge, Sufan Wu, Yong He, Xiaozhou Mou, Chenyang Ye, Yi Sun

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: tumor organoid, tumor microenvironment (TME), precision medicine, multi-omics, exosome (vesicle), CRISPR, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.872531/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/eb110bb8630c4f498cc1aff9281a468f

Organoids: Construction and Application in Gastric Cancer

Authors: Chengdong Huo, Xiaoxia Zhang, Yanmei Gu, Daijun Wang, Shining Zhang, Tao Liu, Yumin Li, Wenting He

Source: Biomolecules, Vol 13, Iss 5, p 875 (2023)

Subject Terms: organoid, tumor organoid, stem cell, 3D cell culture, patient-derived organoids (PDO), Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/13/5/875; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/9c8d9f2711e5445bb56882cd959deb29