Mogroside V enhances bone marrow mesenchymal stem cells osteogenesis under hyperglycemic conditions through upregulating miR-10b-5p and PI3K/Akt signaling.

Authors: Lan, Dongni^1,2, Li, Kongmei^1,2, Ye, Zhimao^1,2, Luo, Yicai^1,2, Li, Cuiping^1,2, Li, Hao^1,2 sherrylee2011@126.com

Source: Journal of Orthopaedic Surgery & Research. 3/14/2025, Vol. 20 Issue 1, p1-9. 9p.

Subject Terms: *TRITERPENES, *BONE marrow, *PHENOMENOLOGICAL biology, *PHOSPHORYLATION, *RESEARCH funding, *MESENCHYMAL stem cells, *BONE growth, *MICRORNA, *BIOCHEMISTRY, *CELLULAR signal transduction, *DESCRIPTIVE statistics, *HYPERGLYCEMIA, *MICE, *BIOINFORMATICS, *GENE expression, *ANIMAL experimentation, *TRANSFERASES

Phytochemical Analysis and Biological Activities of Perenniporia Fraxinea Extracts.

Authors: Tie Lu^1,2,3, Sijia Liu¹, Lihui Liang^2,4, Fumei Wang¹, Xiaoyu Zhang¹, Pengfei Duan¹, Zhaohui Xie¹, Xiaofeng Gao^2,3,4 xiaofenggao1981@163.com

Source: Current Topics in Nutraceutical Research. Nov2024, Vol. 22 Issue 4, p1126-1131. 6p.

Subject Terms: *Research funding, Triterpenes, Petroleum, Flavonoids, Phytochemicals, Biological products, Fungi, Functional foods, Hypoglycemic agents, Plant extracts, Sterols, Hyperglycemia, Antioxidants, Uric acid, Polyphenols

Deciphering the Phytochemical Potential of Hemp Hairy Roots: A Promising Source of Cannabisins and Triterpenes as Bioactive Compounds.

Authors: Kaminsky, Naomi¹ (AUTHOR) h.mailhac@sth-biotech.com, Hubert, Jane² (AUTHOR), Guerin, Cédric³ (AUTHOR), Mazlani, Malak¹ (AUTHOR), Kotland, Alexis² (AUTHOR), Pozzobon, Victor³ (AUTHOR), Marant, Blandine⁴ (AUTHOR), Mailhac, Héloïse¹ (AUTHOR), Poigny, Stéphane⁵ (AUTHOR)

Source: Molecules. Dec2024, Vol. 29 Issue 23, p5792. 22p.

Subject Terms: *TRITERPENES, *BIOACTIVE compounds, *MEDICINAL plants, *HERBACEOUS plants, *BIOTECHNOLOGY, *TERPENES

Cytotoxic Autophagy: A Novel Treatment Paradigm against Breast Cancer Using Oleanolic Acid and Ursolic Acid.

Authors: Gupta, Kunj Bihari¹ (AUTHOR) kugupta@augusta.edu, Gao, Jie^1,2 (AUTHOR) gaoj@uab.edu, Li, Xin^1,3 (AUTHOR) xli@cau.edu, Thangaraju, Muthusamy⁴ (AUTHOR) mthangaraju@augusta.edu, Panda, Siva S.^4,5 (AUTHOR) sipanda@augusta.edu, Lokeshwar, Bal L.¹ (AUTHOR) blokeshwar@augusta.edu

Source: Cancers. Oct2024, Vol. 16 Issue 19, p3367. 17p.

Subject Terms: *THERAPEUTIC use of antineoplastic agents, *TRITERPENES, *PROTEIN kinase inhibitors, *URSOLIC acid, *AUTOPHAGY, *RESEARCH funding, *PROTEIN kinases, *PHOSPHORYLATION, *BREAST tumors, *ANTINEOPLASTIC agents, *APOPTOSIS, *CELL proliferation, *CELLULAR signal transduction, *CELL lines, *PARADIGMS (Social sciences), *GENE expression, *DRUG efficacy, *CELL survival, *PHARMACODYNAMICS

Tubeimoside-1 Inhibits Pancreatic Tumor Cell Growth and Enhances Tumor Cell Sensitivity to Gemcitabine.

Authors: Jun Wang¹, Shi Wang¹, Xiaopeng Fan¹, Hailin Ye¹ yehailin4030501@163.com

Source: Current Topics in Nutraceutical Research. Aug2024, Vol. 22 Issue 3, p861-867. 7p.

Subject Terms: *Research funding, Triterpenes, Drug resistance in cancer cells, Chalones, Antineoplastic agents, Apoptosis, Biological products, Tumor markers, Treatment effectiveness, Pancreatic tumors, Cell lines, Cancer chemotherapy, Plant extracts, Gene expression, Gemcitabine, Glycosides, Medicinal plants, mTOR inhibitors, Rapamycin, Pharmacodynamics

Engineered poplar for bioproduction of the triterpene squalene.

Authors: Bibik, Jacob D.^1,2,3 (AUTHOR), Sahu, Abira^4,5 (AUTHOR), Kim, Boeun^2,6 (AUTHOR), Unda, Faride^2,7 (AUTHOR), Andersen, Trine B.^2,3 (AUTHOR), Mansfield, Shawn D.^2,7,8 (AUTHOR), Maravelias, Christos T.^6,9 (AUTHOR), Sharkey, Thomas D.^3,4,5 (AUTHOR), Hamberger, Björn R.^1,2,3 (AUTHOR) hamberge@msu.edu

Source: Plant Biotechnology Journal. Aug2024, Vol. 22 Issue 8, p2301-2311. 11p.

Subject Terms: *SQUALENE, *TRITERPENES, *POPLARS, *SPECIALTY chemicals, *ROOT formation, *FOSSIL fuels

The Pharmacological Mechanisms Underlying the Protective Effect of Ginsenoside Rg3 against Heart Failure.

Authors: Jia, Yanan¹ (AUTHOR), Gong, Miao¹ (AUTHOR), Ke, Zunping¹ (AUTHOR) kzprenmin@163.com, Luo, Zhiwen¹ (AUTHOR)

Source: Cardiology Research & Practice. 7/30/2024, Vol. 2024, p1-9. 9p.

Subject Terms: *TRITERPENES, *ADIPOKINES, *ANTI-inflammatory agents, *RESEARCH funding, *CARDIOTONIC agents, *PHARMACEUTICAL chemistry, *POLYMERASE chain reaction, *HEART failure, *CELLULAR signal transduction, *GENE expression, *GLYCOSIDES, *MOLECULAR structure, *ONTOLOGIES (Information retrieval), *INFLAMMATION, *CYTOKINES, *STAT proteins, *INTERLEUKINS, *TUMOR necrosis factors, *CASPASES, *PHARMACODYNAMICS

Triterpenoids from Juglans mandshurica with anti-hyaluronidase activities.

Authors: Qi, Ze-Chen¹, Chen, Qiu-Han², Xu, Zeng¹, Yang, Chen² yangchenczspine@163.com

Source: Journal of Asian Natural Products Research. Jul2024, Vol. 26 Issue 7, p773-779. 7p.

Subject Terms: *TRITERPENES, *WALNUT, *IN vitro studies, *STATISTICAL correlation, *NUCLEAR magnetic resonance spectroscopy, *COLORIMETRY, *PHYTOCHEMICALS, *MEDICINAL plants, *MASS spectrometry, *MOLECULAR structure, *RESEARCH, *GLYCOSIDASES, *CHROMATOGRAPHIC analysis, *CHEMICAL inhibitors

Geographic Terms: CHINA

Unraveling the Impact of Six Pentacyclic Triterpenes Regulating Metabolic Pathways on Lung Carcinoma Cells.

Authors: Torres-Sanchez, Anamaris^1,2 (AUTHOR) anamaris.torres@upr.edu, Torres, Grace³ (AUTHOR) daraishkapc@sanjuanbautista.edu, Estrada, Sthephanie⁴ (AUTHOR) sthephanie.estrada@upr.edu, Perez, Daraishka³ (AUTHOR) eddianva@sanjuanbautista.edu, Garcia, Carlos⁵ (AUTHOR), Milian, Melissa³ (AUTHOR) valeriemp@sanjuanbautista.edu, Velazquez, Eddian³ (AUTHOR), Molina, Valerie³ (AUTHOR), Delgado, Yamixa³ (AUTHOR) ydelgado@sanjuanbautista.edu

Source: Pharmaceuticals (14248247). Jun2024, Vol. 17 Issue 6, p694. 19p.

Subject Terms: *LUNGS, *TRITERPENES, *BETULINIC acid, *POISONS, *RIBONUCLEOSIDE diphosphate reductase, *BETULIN

Triterpenoids from the hook-bearing stems of Uncaria rhynchophylla.

Authors: Liu, Xin-Yu¹, Tong, Xin-Nuo¹, Liang, Xiao-Min¹, Guo, Qiang², Tu, Peng-Fei¹, Zhang, Qing-Ying¹ qyzhang@bjmu.edu.cn

Source: Journal of Asian Natural Products Research. Jun2024, Vol. 26 Issue 6, p747-755. 9p.

Subject Terms: *ORGANIC compound analysis, *TRITERPENES, *IN vitro studies, *HIGH performance liquid chromatography, *RESEARCH funding, *PLANT stems, *HYDROCARBONS, *PHYTOCHEMICALS, *DESCRIPTIVE statistics, *MEDICINAL plants, *MOLECULAR structure, *CELL death, *MASS spectrometry, *ANALYTICAL chemistry

Antibacterial lanostane triterpenoids from Ganoderma tsugae.

Authors: Hu, Jiang¹, Li, Guo-Fen², Xu, Feng-Ming³, Li, Qiang¹, Lv, Tao¹, Peng, Tian-Feng¹, Yin, Si¹, Gong, Wei⁴ gongwei142857@163.com

Source: Journal of Asian Natural Products Research. May2024, Vol. 26 Issue 5, p541-547. 7p.

Subject Terms: *TRITERPENES, *PLANT anatomy, *IN vitro studies, *TRADITIONAL medicine, *NUCLEAR magnetic resonance spectroscopy, *FUNCTIONAL foods, *PHYTOCHEMICALS, *PLANTS, *PLANT extracts, *ANTI-infective agents, *EXPERIMENTAL design, *MOLECULAR structure, *GRAM-positive bacteria, *PHARMACODYNAMICS

Determination of Chlorogenic Acid, Geniposide, Total Flavonoids and Total Triterpenes in Wulan-13.

Authors: Xiaohua WU¹, Burenbatu²

Source: Medicinal Plant. Apr2024, Vol. 15 Issue 2, p6-9. 4p.

Subject Terms: *CHLOROGENIC acid, *TRITERPENES, *FLAVONOIDS

Phytochemical and Metabolomic Investigation of a Popular Traditional Plant from La Réunion: Psiloxylon mauritianum.

Authors: Ozga, Théo¹, patrick.carriere-richez@univ-reunion.frtheo.ozga@univ-reunion.fr, Herbette, Gaëtan^2,3, gaetan.herbette@cnrs.frjerome.bignon@cnrs.fr, Carriere Richez, Patrick^1,4, juliano_haddad@outlook.compatricia.clerc@univ-reunion.fr, Clerc, Patricia¹, jacqueline.smadja@univ-reunion.fr, Haddad, Juliano⁴, chaker.el-kalamouni@univ-reunion.fr, El Kalamouni, Chaker⁴, Bignon, Jérôme³, Marcellin-Gros, Rémy^5,6, remy.marcellin-gros@unige.ch, Ferreira Queiroz, Emerson^5,6, emerson.ferreira@unige.ch, Wolfender, Jean-Luc^5,6, jean-luc.wolfender@unige.ch, Smadja, Jacqueline¹, Gauvin-Bialecki, Anne¹, theo.ozga@univ-reunion.fr

Source: Applied Sciences (2076-3417); Jan2025, Vol. 15 Issue 2, p496, 17p

Pseudoamaolide P, a 1,2:3,4:9,10:9,19-tetraseco-cycloartane triterpene spiroketal lactone from seeds of Pseudolarix amabilis.

Authors: Zhu, Yu-Xun¹, Wang, Shang-Yi¹, Yang, Cheng-Shuo¹, Zhang, Zhao-Xin¹, Zhang, Huan-Ping¹, Chai, Li-Sha¹, Su, Guo-Zhu¹, Li, Yong¹ liyong@imm.ac.cn

Source: Journal of Asian Natural Products Research. Feb2024, Vol. 26 Issue 2, p195-203. 9p.

Subject Terms: *TRITERPENES, *NF-kappa B, *STATISTICAL correlation, *NUCLEAR magnetic resonance spectroscopy, *RESEARCH funding, *CELLULAR signal transduction, *DESCRIPTIVE statistics, *PLANT extracts, *SEEDS, *MASS spectrometry, *CHROMATOGRAPHIC analysis

Two new baccharane triterpenes isolated from Rhus chinensis.

Authors: Wang, Hong-Qing¹, Lai, Sheng-Tian¹, Liu, Jian-Bo¹, Shao, Hong-Jie¹, Chen, Ruo-Yun¹, Kang, Jie¹ jiekang@imm.ac.cn

Source: Journal of Asian Natural Products Research. Feb2024, Vol. 26 Issue 2, p189-194. 6p.

Subject Terms: *TRITERPENES, *NUCLEAR magnetic resonance spectroscopy, *RESEARCH funding, *PLANT extracts, *RATS, *MEDICINAL plants, *X-rays, *MOLECULAR structure, *ANIMAL experimentation

Analysis of vitamin D receptor binding affinities of enzymatically synthesized triterpenes including ambrein and unnatural onoceroids.

Authors: Ueda, Daijiro¹ (AUTHOR), Matsuda, Natsu¹ (AUTHOR), Takaba, Yuka¹ (AUTHOR), Hirai, Nami¹ (AUTHOR), Inoue, Mao¹ (AUTHOR), Kameya, Taichi¹ (AUTHOR), Abe, Tohru¹ (AUTHOR), Tagaya, Nao² (AUTHOR), Isogai, Yasuhiro² (AUTHOR), Kakihara, Yoshito³ (AUTHOR), Bartels, Florian⁴ (AUTHOR), Christmann, Mathias⁴ (AUTHOR), Shinada, Tetsuro⁵ (AUTHOR), Yasuda, Kaori² (AUTHOR) kyasuda@pu-toyama.ac.jp, Sato, Tsutomu¹ (AUTHOR) satot@agr.niigata-u.ac.jp

Source: Scientific Reports. 1/16/2024, Vol. 14 Issue 1, p1-10. 10p.

Subject Terms: *VITAMIN D receptors, *TRITERPENES, *BACILLUS megaterium, *VITAMIN D, *BIOMOLECULES, *STRUCTURE-activity relationships

Structurally diverse triterpenoid alkaloids from Buxus rugulosa.

Authors: Wang, Yu-Huan¹, Cui, Le-Tian¹, Sun, Yu-Jin¹, Li, Yong-Yi¹, Luo, Jun¹, Kong, Ling-Yi¹ cpu_lykong@126.com

Source: Journal of Asian Natural Products Research. Jan2024, Vol. 26 Issue 1, p18-25. 8p.

Subject Terms: *TRITERPENES, *IN vitro studies, *ALKALOIDS, *NUCLEAR magnetic resonance spectroscopy, *RESEARCH funding, *ETHANOL, *PLANT stems, *PLANT extracts, *CELL lines, *MOLECULAR structure, *ELECTROSPRAY ionization mass spectrometry, *LEAVES

New triterpenoids from the aerial parts of the Uygur medicine Salvia deserta.

Authors: Ren, Xue¹, Yuan, Xin¹, Chen, Yu-Ying¹, Zhang, Qiao-Zhuo¹, Tan, Chun-Lin¹, Kang, Juan-Juan¹, Luo, Shi-Hong², Liu, Yan¹, Guo, Kai¹ guokai@cdutcm.edu.cn, Li, Sheng-Hong^1,3 shli@cdutcm.edu.cn

Source: Journal of Asian Natural Products Research. Jan2024, Vol. 26 Issue 1, p78-90. 13p.

Subject Terms: *DRUG therapy for angina pectoris, *TRITERPENES, *PLANT anatomy, *CHINESE medicine, *IN vitro studies, *MACROPHAGES, *CORONARY disease, *RESEARCH funding, *HYPERTENSION, *HYDROCARBONS, *FLAVONOIDS, *PLANT extracts, *MOLECULAR structure, *CYTOKINES, *TUMOR necrosis factors, *INTERLEUKINS, *IMMUNOSUPPRESSION

Ursolic Acid Inhibited Cholesterol Esterase and Pancreatic Lipase Activities and Decreased Micellar Cholesterol Solubility In Vitro.

Authors: Jiang, Wenjing¹ (AUTHOR), Huang, Qun² (AUTHOR), Meng, Xiangxing¹ (AUTHOR), Rehman, Rizwan-ur³ (AUTHOR), Qian, Kun¹ (AUTHOR), Yang, Xu⁴ (AUTHOR), Liu, Xiaozhi⁵ (AUTHOR), Chen, Jingnan⁶ (AUTHOR), Zhang, Ye¹ (AUTHOR), Li, Jing¹ (AUTHOR), Wang, Jilite⁷ (AUTHOR), Guo, Qingbin¹ (AUTHOR), Liu, Suwen⁸ (AUTHOR), Wang, Hao¹ (AUTHOR)

Source: Journal of Food Biochemistry. 12/27/2023, p1-16. 16p.

Subject Terms: Ursolic acid, Triterpenes, Van der Waals forces, Hydrophobic interactions, Cholesterol, Lipases, Binding sites

Health Benefits of Olive Leaf: The Focus on Efficacy of Antiglycation Mechanisms.

Authors: Demirer, Büşra¹, Samur, Gülhan²

Source: Nutrition Reviews. Mar2025, Vol. 83 Issue 3, p551-561. 11p.

Subject Terms: *FOLIAR diagnosis, *TRITERPENES, *ANTI-inflammatory agents, *LIGANDS (Biochemistry), *OLIVE, *FLAVONOIDS, *ANTINEOPLASTIC agents, *HYPOGLYCEMIC agents, *ANTIHYPERTENSIVE agents, *PLANT extracts, *PHENOLS, *ANTIOXIDANTS, *DRUG efficacy, *ANTIGLYCATION agents, *ORGANIC compounds