Tanshinone I Ameliorates Psoriasis-Like Dermatitis by Suppressing Inflammation and Regulating Keratinocyte Differentiation

Authors: Wang Q, Luo X, Su Y, Jin Y, Kuang Q, Li S, Shen W, Zhu Y

Source: Drug Design, Development and Therapy, Vol Volume 19, Pp 539-552 (2025)

Subject Terms: psoriasis, tanshinone i, immune modulation, keratinocyte, apoptosis., Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/tanshinone-i-ameliorates-psoriasis-like-dermatitis-by-suppressing-infl-peer-reviewed-fulltext-article-DDDT; https://doaj.org/toc/1177-8881

Access URL: https://doaj.org/article/ed392a0fa2cb486f8885670cbcadf9aa

Tan I modulates astrocyte inflammatory responses through enhanced NAD+–Sirt1 pathway: Insights from metabolomics studies

Authors: Zhao, Feng-Lun ^{a, b, 1}, Zhang, Jia-Rui ^{b, 1}, Liu, Man-Hua ^{c, 1}, Liu, Hui-Yi ^{a, b}, Mao, Cheng-Jie ^a, Wang, Fen ^{a, b}, Chen, Ju-Ping ^{c, ⁎}, Liu, Chun-Feng ^{a, b, ⁎⁎}

Source: In International Immunopharmacology 4 April 2025 151

Integrated identification and mechanism exploration of bioactive ingredients from Salvia miltiorrhiza to induce vascular normalization

Authors: Qian, Cheng ^{a, b, 1}, Huang, Ying ^{a, 1}, Zhang, Shan ^a, Yang, Chunmei ^{a, b}, Zheng, Weiwei ^{a, b}, Tang, Weiwei ^c, Wan, Guiping ^c, Wang, Aiyun ^{a, d, ⁎}, Lu, Yin ^{a, d, ⁎}, Zhao, Yang ^{a, b, ⁎}

Source: In Phytomedicine March 2025 138

Tanshinone I reprograms glycolysis metabolism to regulate histone H3 lysine 18 lactylation (H3K18la) and inhibits cancer cell growth in ovarian cancer

Authors: Jin, Zhou ^{a, b, 1}, Yun, Lin ^{c, 1}, Cheng, Peng ^{a, b, d, ⁎}

Source: In International Journal of Biological Macromolecules February 2025 291

Tanshinone I improves renal fibrosis by promoting gluconeogenesis through upregulation of peroxisome proliferator-activated receptor-γ coactivator 1α

Authors: Yanfang Bai, Hui Wen, Junyan Lin, Xinying Liu, Hua Yu, Ming Wu, Ling Wang, Dongping Chen

Source: Renal Failure, Vol 46, Iss 2 (2024)

Subject Terms: Tanshinone I, gluconeogenesis, PGC1α, renal fibrosis, chronic kidney disease, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: https://doaj.org/toc/0886-022X; https://doaj.org/toc/1525-6049

Access URL: https://doaj.org/article/99fa4e78c92749adb5813f8a213ac593

Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC

Authors: Jia Zhao, Hongbin Liu, Zhixian Hong, Wei Luo, Wenqing Mu, Xiaorong Hou, Guang Xu, Zhie Fang, Lutong Ren, Tingting Liu, Jincai Wen, Wei Shi, Ziying Wei, Yongping Yang, Wenjun Zou, Jun Zhao, Xiaohe Xiao, Zhaofang Bai, Xiaoyan Zhan

Source: Molecular Medicine, Vol 29, Iss 1, Pp 1-13 (2023)

Subject Terms: Tanshinone I, NLRP3 inflammasome, ASC, LPS-induced septic shock, NASH, Therapeutics. Pharmacology, RM1-950, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1528-3658

Access URL: https://doaj.org/article/0c601d467d784d07974ca8fb445f6416

Tanshinone-I for the treatment of uterine fibroids: Molecular docking, simulation, and density functional theory investigations

Authors: Abhishek Tiwari, Varsha Tiwari, Ajay Sharma, Deependra Singh, Manju Singh Rawat, Tarun Virmani, Reshu Virmani, Girish Kumar, Manish Kumar, Abdulsalam Alhalmi, Omar M. Noman, Ramzi A. Mothana, Mohammad Alali

Source: Saudi Pharmaceutical Journal, Vol 31, Iss 6, Pp 1061-1076 (2023)

Subject Terms: Uterine fibroids, Molecular modelling, Tanshinone-I, Progesterone blocker, Docking, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1319016423001202; https://doaj.org/toc/1319-0164

Access URL: https://doaj.org/article/5ebc74edaaef42e8ab9d825a7c346826

Tanshinone I alleviates steroid-induced osteonecrosis of femoral heads and promotes angiogenesis: in vivo and in vitro studies

Authors: Kai Sun, Yuman Xue, Xin Zhang, Xiaodong Li, Jun Zhao, Xilin Xu, Xiaofeng Zhang, Fubiao Yang

Source: Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-15 (2023)

Subject Terms: Steroid, Osteonecrosis of the femoral head, Tanshinone I, Angiogenesis, SRY-box transcription factor 11, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1749-799X

Access URL: https://doaj.org/article/1aa755eabcda4f51bff79529a7fc5299

Tanshinone I suppresses hepatocellular carcinoma cells growth through targeting DNA double-strand break repair

Authors: Zhen Qian, Nannan Feng, Anke Geng

Source: Cancer Biology & Therapy, Vol 24, Iss 1 (2023)

Subject Terms: tanshinone i, hepatocellular carcinoma (hcc), double strand break repair, homologous recombination, non-homologous end joining, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1538-4047; https://doaj.org/toc/1555-8576

Access URL: https://doaj.org/article/355daf3ee6844353ae498d5642c1ee3a

Effect of Harvest Time on Growth and Bioactive Compounds in Salvia miltiorrhiza

Authors: Zhiheng Xing, Guihong Bi, Tongyin Li, Qianwen Zhang, Patricia R. Knight

Source: Plants, Vol 13, Iss 13, p 1788 (2024)

Subject Terms: danshen, havest time, tanshinone I, tanshinone IIA, cryptotanshinone, salvianolic acid B, Botany, QK1-989

File Description: electronic resource

Relation: https://www.mdpi.com/2223-7747/13/13/1788; https://doaj.org/toc/2223-7747

Access URL: https://doaj.org/article/61c826d87d584687a527eb3fd65d3d70

Effect of Plant Density on Growth and Bioactive Compounds in Salvia miltiorrhiza

Authors: Zhiheng Xing, Guihong Bi, Tongyin Li, Qianwen Zhang, Patricia R. Knight

Source: Agronomy, Vol 14, Iss 6, p 1157 (2024)

Subject Terms: density, danshen, salvianolic acid B, tanshinone I, cryptotanshinone, tanshinone IIA, Agriculture

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4395/14/6/1157; https://doaj.org/toc/2073-4395

Access URL: https://doaj.org/article/07207205246d425d94e70f8840d51e62

Combined Treatment of Tanshinone I and Epirubicin Revealed Enhanced Inhibition of Hepatocellular Carcinoma by Targeting PI3K/AKT/HIF-1&alpha

Authors: Zhao J, Lin E, Cai C, Zhang M, Li D, Cai S, Zeng G, Yin Z, Wang B, Li P, Hong X, Chen J, Zou B, Li J

Source: Drug Design, Development and Therapy, Vol Volume 16, Pp 3197-3213 (2022)

Subject Terms: hepatocellular carcinoma, epirubicin, tanshinone i, hif-1α, resistance, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/combined-treatment-of-tanshinone-i-and-epirubicin-revealed-enhanced-in-peer-reviewed-fulltext-article-DDDT; https://doaj.org/toc/1177-8881

Access URL: https://doaj.org/article/0bf42c913a9f484c9cd9bd3fc2f14f7c

Tanshinone I attenuates fibrosis in fibrotic kidneys through down-regulation of inhibin beta-A

Authors: Ming Wu, Feng Yang, Di Huang, Chaoyang Ye

Source: BMC Complementary Medicine and Therapies, Vol 22, Iss 1, Pp 1-12 (2022)

Subject Terms: Tanshinone I, Renal fibrosis, INHBA, CKD, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://doaj.org/toc/2662-7671

Access URL: https://doaj.org/article/a6994e0e6f284970b629c7e8e872348e

Protective effects of tanshinone I against cisplatin-induced nephrotoxicity in mice

Authors: Yan Wang, Yun-hui Zhang, Yin-ru Tang, Jie Lan, Zhi-ying Huang, Wei Tian, Qian Huang, Yan Peng, Yuan Gao, Yue-qin Hu, Xue-nong Zhang

Source: Iranian Journal of Basic Medical Sciences, Vol 25, Iss 3, Pp 414-418 (2022)

Subject Terms: cisplatin, mice, nephrotoxicity, oxidative stress, tanshinone ⅰ, Medicine

File Description: electronic resource

Relation: https://ijbms.mums.ac.ir/article_19684_a82c570fe439519ce9ca957e32f72d43.pdf; https://doaj.org/toc/2008-3866; https://doaj.org/toc/2008-3874

Access URL: https://doaj.org/article/4a6ef5b1217c418b9de681913c8cf48e

Tanshinone I inhibited growth of human chronic myeloid leukemia cells via JNK/ERK mediated apoptotic pathways

Authors: Sun, Siya, Zhu, Lingyan, Lai, Mengru, Cheng, Rubin, Ge, Yuqing

Source: Brazilian Journal of Medical and Biological Research. January 2021 54(8)

Subject Terms: Tanshinone I, Chronic myeloid leukemia, K562, Apoptosis, JNK/ERK signaling pathway

File Description: text/html

Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2021000800611

Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathway

Authors: Youqiong Zhuo, Renyikun Yuan, Xinxin Chen, Jia He, Yangling Chen, Chenwei Zhang, Kaili Sun, Shilin Yang, Zhenjie Liu, Hongwei Gao

Source: Chinese Medicine, Vol 16, Iss 1, Pp 1-15 (2021)

Subject Terms: Tanshinone I, Oxidative stress, Necroptosis, Myocardial ischemia reperfusion, RIP1/RIP3/MLKL, Akt/Nrf2, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://doaj.org/toc/1749-8546

Access URL: https://doaj.org/article/21aa3805aab1455483d67bab35e40a77

Research and Development of Natural Product Tanshinone I: Pharmacology, Total Synthesis, and Structure Modifications

Authors: Xing Huang, Lili Jin, Hao Deng, Dan Wu, Qing-kun Shen, Zhe-shan Quan, Chang-hao Zhang, Hong-Yan Guo

Source: Frontiers in Pharmacology, Vol 13 (2022)

Subject Terms: tanshinone I, pharmacology, total synthesis, structure-modifications, danshen, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.920411/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/ff6b6ed158584c8cb0cbe185554b1918

Therapeutic and pharmacological potential of Tanshinones against lung cancer: A systematic review

Authors: Syed Sahajada Mahafujul Alam, Faizan Uddin, Farheen Badrealam Khan, Mohammad Amjad Kamal, Mehboob Hoque

Source: Phytomedicine Plus, Vol 2, Iss 1, Pp 100202- (2022)

Subject Terms: Tanshinones, Tanshinone I, Tanshinone IIA, Cryptotanshinone, Lung cancer, Systematic review, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2667031321001846; https://doaj.org/toc/2667-0313

Access URL: https://doaj.org/article/e88c17f86c1a4d24b69dd42fbd0cc5b9

Nitrogen Fertilization Improves Growth and Bioactive Compound Content for Salvia miltiorrhiza Bunge

Authors: Zhiheng Xing, Guihong Bi, Tongyin Li, Qianwen Zhang, Patricia R. Knight

Source: Horticulturae, Vol 9, Iss 2, p 254 (2023)

Subject Terms: danshen, nitrogen, tanshinone I, tanshinone IIA, cryptotanshinone, salvianolic acid, Plant culture, SB1-1110

File Description: electronic resource

Relation: https://www.mdpi.com/2311-7524/9/2/254; https://doaj.org/toc/2311-7524

Access URL: https://doaj.org/article/ef380c17afe747b69b2e859ed66d5f87

Plant Growth and the Contents of Major Bioactive Compounds of Salvia miltiorrhiza Bunge Grown in Mississippi, United States

Authors: Zhiheng Xing, Guihong Bi, Tongyin Li, Qianwen Zhang, Patricia R. Knight

Source: Horticulturae, Vol 9, Iss 3, p 310 (2023)

Subject Terms: danshen, roots, tanshinone I, tanshinone IIA, cryptotanshinone, salvianolic acid B, Plant culture, SB1-1110

File Description: electronic resource

Relation: https://www.mdpi.com/2311-7524/9/3/310; https://doaj.org/toc/2311-7524

Access URL: https://doaj.org/article/c200a8a066114007a5e61546d00410b6