Simeprevir induces ferroptosis through β-TrCP/Nrf2/GPX4 axis in triple-negative breast cancer cells

Authors: Lin, Zhirong ^{a, 1}, Liu, Zifei ^{a, 1}, Yang, Xinyu ^{a, 1}, Pan, Zhilong ^a, Feng, Yaxin ^a, Zhang, Yunyi ^a, Chen, Huiping ^a, Lao, Liyan ^a, Chen, Jianing ^a, Shi, Fujun ^{b, ⁎}, Gong, Chang ^{a, ⁎}, Zeng, Wenfeng ^{a, ⁎}

Source: In Biomedicine & Pharmacotherapy November 2024 180

Simeprevir restores the anti-Staphylococcus activity of polymyxins

Authors: Yuan Wu, Pingyun Wu, Ruolan Wu, Huilong Li, Yao Duan, Chaoni Cai, Zixin Liu, Pengfei She, Di Zhang

Source: AMB Express, Vol 13, Iss 1, Pp 1-14 (2023)

Subject Terms: Staphylococcus aureus, Simeprevir, Polymyxins, Antimicrobial, Drug repurposing, Persister cells, Biotechnology, TP248.13-248.65, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2191-0855

Access URL: https://doaj.org/article/084e7f24b017455b9efcf31ddc022643

Mathematical processing of absorption as green smart spectrophotometric methods for concurrent assay of hepatitis C antiviral drugs, Sofosbuvir and Simeprevir: application to combined pharmaceutical dosage forms and evaluation of the method greenness

Authors: Sayed M. Derayea, Ahmed A. Abu-hassan, Ahmed A. Hamad, Walid E. Eltoukhi, Amal E. Hamad, Bassam Shaaban Mohammed

Source: BMC Chemistry, Vol 17, Iss 1, Pp 1-10 (2023)

Subject Terms: Simeprevir, Sofosbuvir, Iso-absorptive point method, Ratio subtraction method, Dual wavelength method, Combined pharmaceutical dosage forms, Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2661-801X

Access URL: https://doaj.org/article/e1241db116a54fa0a77ffcbe42fcb6d8

DAA - directly acting antivirals - as a new, more efficient solution of the chronic hepatitis C treatment and theirs various application.

Authors: Kamila Abram, Patryk Banaś, Justyna Adamus, Jakub Rafał Pierzchała, Katarzyna Bednarz, Natalia Sobańska, Aleksandra Paulina Banasiak, Rafał Teichman, Jakub Kasprowicz, Michał Hyjek

Source: Journal of Education, Health and Sport, Vol 13, Iss 3 (2023)

Subject Terms: simeprevir, sofosbuvir, velpatasvir, telaprevir, chronic hepatitis C, Education, Sports, GV557-1198.995, Medicine

File Description: electronic resource

Relation: https://apcz.umk.pl/JEHS/article/view/41811; https://doaj.org/toc/2391-8306

Access URL: https://doaj.org/article/79d969a0fd414b9188e61612d6eb13d1

Remission of long-term hepatic and renal disease induced by HCV after direct-acting antivirals therapy

Authors: Arruda, Raissa M, Batista, Andrea D, Filgueira, Norma A, Moura, Izolda F, Sette, Luis H, Lopes, Edmundo P

Source: Brazilian Journal of Nephrology. March 2021 43(1)

Subject Terms: Hepacivirus, Glomerulonephritis, Sofosbuvir, Simeprevir, Cryoglobulinemia

File Description: text/html

Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000100117

Evaluation of the genetic toxicity of sofosbuvir and simeprevir with and without ribavirin in a human-derived liver cell line

Authors: LIBRELOTTO, CARINA S., SOUZA, ANA PAULA DE, ÁLVARES-DA-SILVA, MÁRIO R., SIMON, DANIEL, DIHL, RAFAEL R.

Source: Anais da Academia Brasileira de Ciências. January 2021 93(4)

Subject Terms: direct-acting antiviral, micronucleus test, sofosbuvir (CAS 1190307-88-0), simeprevir (CAS 923604-59-5), ribavirin (CAS 36791–04–5)

File Description: text/html

Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652021000700601

Remission of long-term hepatic and renal disease induced by HCV after direct-acting antivirals therapy

Authors: Raissa M Arruda, Andrea D Batista, Norma A Filgueira, Izolda F Moura, Luis H Sette, Edmundo P Lopes

Source: Brazilian Journal of Nephrology, Vol 43, Iss 1, Pp 117-120 (2020)

Subject Terms: Hepacivirus, Glomerulonephritis, Sofosbuvir, Simeprevir, Cryoglobulinemia, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000100117&tlng=pt; http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000100117&tlng=en; https://doaj.org/toc/2175-8239

Access URL: https://doaj.org/article/c3671f0bc489489cb6411c9dc7015602

Safety and efficacy of the combination simeprevir-sofosbuvir in HCV genotype 1- and 4-mono-infected patients from the French ANRS CO22 hepather cohort

Authors: Anne Laurain, Sophie Metivier, Georges Haour, Dominique Larrey, Céline Dorival, Christophe Hezode, Fabien Zoulim, Patrick Marcellin, Marc Bourliere, Jean-Pierre Zarski, Dominique Thabut, Laurent Alric, Nathalie Ganne-Carrie, Paul Cales, Jean-Pierre Bronowicki, Ghassan Riachi, Claire Geist, Xavier Causse, Armand Abergel, Olivier Chazouilleres, Philippe Mathurin, Dominique Guyader, Didier Samuel, Albert Tran, Véronique Loustaud-Ratti, Ventzislava Petrov-Sanchez, Alpha Diallo, Clovis Luzivika-Nzinga, Hélène Fontaine, Fabrice Carrat, Stanislas Pol, on behalf of the ANRS/AFEF HEPATHER study group

Source: BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-12 (2019)

Subject Terms: Direct acting antivirals, Hepatitis C virus, Real life cohort, Simeprevir, Sofosbuvir, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12879-019-3923-5; https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/7d26ddf8a567415e8bf3ac4e315b2fa7

Evaluation of the genetic toxicity of sofosbuvir and simeprevir with and without ribavirin in a human-derived liver cell line

Authors: CARINA S. LIBRELOTTO, ANA PAULA DE SOUZA, MÁRIO R. ÁLVARES-DA-SILVA, DANIEL SIMON, RAFAEL R. DIHL

Source: Anais da Academia Brasileira de Ciências, Vol 93, Iss 4 (2021)

Subject Terms: direct-acting antiviral, micronucleus test, sofosbuvir (CAS 1190307-88-0), simeprevir (CAS 923604-59-5), ribavirin (CAS 36791–04–5), Science

File Description: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652021000700601&tlng=en; https://doaj.org/toc/1678-2690

Access URL: https://doaj.org/article/c22e7178303c4ee4b48e809517429bfe

Effectiveness of chronic hepatitis C treatment with direct-acting antivirals in the Public Health System in Brazil

Authors: Holzmann, Iandra, Tovo, Cristiane V., Minmé, Roseline, Leal, Mônica P., Kliemann, Michele P., Ubirajara, Camila, Aquino, Amanda A., Araujo, Bruna, Almeida, Paulo R.L.

Source: Brazilian Journal of Infectious Diseases. August 2018 22(4)

Subject Terms: Sofosbuvir, Daclatasvir, Simeprevir, DAA, Sustained virological response

File Description: text/html

Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000400317

Simeprevir, daclatasvir, and sofosbuvir for hepatitis C virus‐infected patients: Long‐term follow‐up results from the open‐label, Phase II IMPACT study

Authors: Eric Lawitz, Fred Poordad, Julio A. Gutierrez, Maria Beumont, Greet Beets, Ann Vandevoorde, Pieter Van Remoortere, Donghan Luo, Leen Vijgen, Veerle Van Eygen, Mohamed Gamil

Source: Health Science Reports, Vol 3, Iss 2, Pp n/a-n/a (2020)

Subject Terms: decompensation, hepatitis C, portal hypertension, simeprevir, sofosbuvir, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2398-8835

Access URL: https://doaj.org/article/61e6a0119abd4699b62cba409899ce21

Multicenter Experience using Ledipasvir/Sofosbuvir ± RBV to Treat HCV GT 1 Relapsers after Simeprevir and Sofosbuvir Treatment

Authors: Bashar Aqel, Michael Leise, Hugo E. Vargas, Kymberly D. Watt, Andrew P. Keaveny, Nan Zhang, Surakit Pungpapong

Source: Annals of Hepatology, Vol 17, Iss 5, Pp 815-821 (2018)

Subject Terms: Hepatitis C, Direct acting antiviral agents (DAA), Simeprevir, Sofosbuvir, Ledipasvir, Relapser, Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1665268119302601; https://doaj.org/toc/1665-2681

Access URL: https://doaj.org/article/3b8d6d4b01af49f395471913ce51f926

The Observed Effect of Gastric Bypass Surgery on Direct-acting Antiviral Treatment: a Case Report

Authors: Elise J. Smolders, Sophie B. Willemse, Omar El-Sherif, Saye Khoo, David M. Burger

Source: Annals of Hepatology, Vol 17, Iss 3, Pp 525-529 (2018)

Subject Terms: Chronic hepatitis C virus infection, Gastric bypass surgery, Direct-acting antivirals, Simeprevir, Pharmacokinetics, Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1665268119302091; https://doaj.org/toc/1665-2681

Access URL: https://doaj.org/article/5ce426b503bb407685976d044e455a3a

Safety and efficacy of combination therapy (Simeprevir/Sofosbuvir) in the treatment of chronic HCV genotype IV patients

Authors: Engy A. Wahsh, Amal K. Hussein, Ahmed A. Gomaa, Mohamed A. Baraka, Mohie Al-deen Abead

Source: Medicine Science, Vol 7, Iss 1, Pp 122-126 (2018)

Subject Terms: Chronic hepatitis C, genotype IV, simeprevir, sofosbuvir, Medicine

File Description: electronic resource

Relation: http://www.ejmanager.com/fulltextpdf.php?mno=272628; https://doaj.org/toc/2147-0634

Access URL: https://doaj.org/article/7f0e991305d544c1863e1ef88d6d4d39

A 3-year follow-up study after treatment with simeprevir in combination with pegylated interferon-α and ribavirin for chronic hepatitis C virus infection

Authors: Fabien Zoulim, Christophe Moreno, Samuel S. Lee, Peter Buggisch, Andrzej Horban, Eric Lawitz, Chris Corbett, Oliver Lenz, Bart Fevery, Thierry Verbinnen, Umesh Shukla, Wolfgang Jessner

Source: Virology Journal, Vol 15, Iss 1, Pp 1-11 (2018)

Subject Terms: Direct-acting antivirals, Hepatitis C virus, Pegylated interferon, Simeprevir, Sustained virologic response, NS3 amino acid substitutions, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12985-018-0936-4; https://doaj.org/toc/1743-422X

Access URL: https://doaj.org/article/12546fb5318c449181ab2d29342193b1

Simeprevir-Based Triple Therapy with Reduced Doses of Pegylated Interferon α-2a Plus Ribavirin for Interferon Ineligible Patients with Genotype 1b Hepatitis C Virus

Authors: Hideyuki Tamai, Yoshiyuki Ida, Akira Kawashima, Naoki Shingaki, Ryo Shimizu, Kosaku Moribata, Tetsushi Nasu, Takao Maekita, Mikitaka Iguchi, Jun Kato, Taisei Nakao, Masayuki Kitano

Source: Gut and Liver, Vol 11, Iss 4, Pp 551-558 (2017)

Subject Terms: hepacivirus, pegylated interferon, ribavirin, simeprevir, interleukin-28b, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://gutnliver.org/journal/view.html?doi=10.5009/gnl16525; https://doaj.org/toc/1976-2283

Access URL: https://doaj.org/article/02fe17e2acce4576aa847db69b8c990f

Simeprevir with peginterferon α-2a/ribavirin for chronic hepatitis C virus genotype 1 infection in treatment-experienced patients: an open-label, rollover study

Authors: Edward J. Gane, Edwin DeJesus, Ewa Janczewska, Jacob George, Moises Diago, Mariliza Hendrique Da Silva, Henk Reesink, Igor Nikitin, Holger Hinrichsen, Stefan Bourgeois, Peter Ferenci, Umesh Shukla, Ronald Kalmeijer, Oliver Lenz, Bart Fevery, Chris Corbett, Maria Beumont, Wolfgang Jessner

Source: BMC Infectious Diseases, Vol 17, Iss 1, Pp 1-13 (2017)

Subject Terms: Chronic hepatitis C, Direct-acting antiviral therapy, Peginterferon, Ribavirin, Safety, Simeprevir, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12879-017-2444-3; https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/3cfa6244d4a94f6ba954c69bc057268c

Virology analysis in HCV genotype 1-infected patients treated with the combination of simeprevir and TMC647055/ritonavir, with and without ribavirin, and JNJ-56914845

Authors: Leen Vijgen, Kim Thys, An Vandebosch, Pieter Van Remoortere, René Verloes, Sandra De Meyer

Source: Virology Journal, Vol 14, Iss 1, Pp 1-10 (2017)

Subject Terms: Hepatitis C virus, Genotype 1, Simeprevir, TMC647055/ritonavir, JNJ-56914845, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12985-017-0760-2; https://doaj.org/toc/1743-422X

Access URL: https://doaj.org/article/b8e56cc302c3411a9f7452c4760b97dc

PROTEASE INHIBITOR NARLAPREVIR IN THERAPY OF HEPATITIS C VIRUS GENOTYPE 1 INFECTION IN TREATMENT-NAÏVE PATIENTS WITHOUT CIRRHOSIS: PHARMACOECONOMIC EVALUATION

Authors: A. V. Rudakova, D. A. Gusev, A. N. Uskov, L. N. Konovalova, Yu. V. Lobzin

Source: Журнал инфектологии, Vol 9, Iss 1, Pp 100-103 (2017)

Subject Terms: chronic hepatitis c, naive patients, simeprevir, narlaprevir, cost, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://journal.niidi.ru/jofin/article/view/568; https://doaj.org/toc/2072-6732

Access URL: https://doaj.org/article/4097a9b5a42043f2badc5e133361a618

Optimizing choice of oral interferon-free treatment for genotype 1 hepatitis C virus using testing for NS5A resistance: a cost-utility analysis from the perspective of the Italian National Health Service

Authors: Westerhout KY, Bouwmeester W, Duchesne I, Pisini M, Piena MA, Damele F, Gueron B, Treur M, Belsey J

Source: ClinicoEconomics and Outcomes Research, Vol Volume 9, Pp 163-172 (2017)

Subject Terms: Hepatitis C, NS5A inhibitor, simeprevir, sofosbuvir, ledipasvir, health economics., Medicine (General), R5-920, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/optimizing-choice-of-oral-interferon-free-treatment-for-genotype-1-hep-peer-reviewed-article-CEOR; https://doaj.org/toc/1178-6981

Access URL: https://doaj.org/article/70954e8a69ac45de8250beaa1b1a7449