Late-Onset Ocular Hypotensive Effect of Ripasudil on Primary Open-Angle Glaucoma

Authors: Sano K, Terauchi R, Fukai K, Ogawa S, Noro T, Tatemichi M, Nakano T

Source: Clinical Ophthalmology, Vol Volume 18, Pp 3905-3912 (2024)

Subject Terms: ripasudil, rock-inhibitor, glaucoma, ocular hypertension, intraocular pressure, Ophthalmology, RE1-994

File Description: electronic resource

Relation: https://www.dovepress.com/late-onset-ocular-hypotensive-effect-of-ripasudil-on-primary-open-angl-peer-reviewed-fulltext-article-OPTH; https://doaj.org/toc/1177-5483

Access URL: https://doaj.org/article/10e01ca7272248cb8b37489b0aad07af

The Protective Effect of Rho-Associated Kinase Inhibitor Eye Drops (Ripasudil) on Corneal Endothelial Cells After Cataract Surgery: A Prospective Comparative Study

Authors: Majed Alkharashi, Mohammed M. Abusayf, Wael Otaif, Abdullah Alkharashi

Source: Ophthalmology and Therapy, Vol 13, Iss 6, Pp 1773-1781 (2024)

Subject Terms: Cataract surgery, Rho-associated kinase inhibitor, Ripasudil, Corneal endothelial cells, Central corneal thickness, Endothelial cell density, Ophthalmology, RE1-994

File Description: electronic resource

Relation: https://doaj.org/toc/2193-8245; https://doaj.org/toc/2193-6528

Access URL: https://doaj.org/article/f2d2c819899247d09805e9759f3ff303

Drug- and Cell-Type-Specific Effects of ROCK Inhibitors as a Potential Cause of Reticular Corneal Epithelial Edema

Authors: Ursula Schlötzer-Schrehardt, Andreas Gießl, Matthias Zenkel, Alexander Bartsch, Naoki Okumura, Noriko Koizumi, Shigeru Kinoshita, Theofilos Tourtas, Friedrich E. Kruse

Source: Cells, Vol 14, Iss 4, p 258 (2025)

Subject Terms: reticular bullous corneal epithelial edema, honeycomb epithelial edema, Rho kinase inhibitor, ROCK inhibitor, ripasudil, netarsudil, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/14/4/258; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/ec412591f1bc4bf08b7e8f520b5fec70

Switching to Brimonidine/Ripasudil Fixed Combination from Brimonidine + Ripasudil

Authors: Inoue K, Shiokawa M, Kunimatsu-Sanuki S, Tomita G, Ishida K

Source: Clinical Ophthalmology, Vol Volume 18, Pp 423-430 (2024)

Subject Terms: adverse reactions, brimonidine/ripasudil, intraocular pressure, fixed combination, switching, usability, Ophthalmology, RE1-994

File Description: electronic resource

Relation: https://www.dovepress.com/switching-to-brimonidineripasudil-fixed-combination-from-brimonidine---peer-reviewed-fulltext-article-OPTH; https://doaj.org/toc/1177-5483

Access URL: https://doaj.org/article/1cd9300e9c4a444b9066928d23855a8a

Evaluating the efficacy of Rho kinase inhibitor eye drops in the management of corneal edema: A single-center retrospective cohort study

Authors: Itay Lavy, Nir Erdinest, Jamel Corredores, Denise Wajnsztajn, David Smadja

Source: Taiwan Journal of Ophthalmology, Vol 14, Iss 1, Pp 88-94 (2024)

Subject Terms: corneal edema, rho kinase inhibitor, ripasudil, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://www.e-tjo.org/article.asp?issn=2211-5056;year=2024;volume=14;issue=1;spage=88;epage=94;aulast=Lavy; https://doaj.org/toc/2211-5056; https://doaj.org/toc/2211-5072

Access URL: https://doaj.org/article/9924ae7f6c5e4585ae1922449cc97d9d

The Challenges and Therapeutic Prospects in Eye Disease

Contributors: Tsai, Chieh-Chih

Subject Terms: hyperthyroidism, strabismus, orbital decompression surgery, artificial intelligence, blepharoptosis, general practitioners, computer-aided diagnosis (CAD), optical coherence tomography, diabetic macular edema, antivascular endothelial growth factors, vitreomacular interface abnormality, eye, optometry, sEMG, eyeball length, retinal, choroidal, intraocular pressure, USG, masticatory muscles, myopia, hydrogel scleral buckles, retinal detachment, glaucoma, anterior orbitotomy, orbital muscle volume, increased orbital muscle, orbital muscle enlargement, orbit volumetry, Graves’ orbitopathy, Graves’ disease, dysthyroid optic neuropathy, orbital decompression, OCT-A, neovascularization, AMD, anti-VEGF, vascular remodeling, personalized, approach, glaucomatous optic neuropathy, glutamate, optic nerve protection, infectious keratitis, corneal ulcer, Photoactivated Chromophore Corneal Collagen Cross-Linking, PACK-CXL, IgG4-related ophthalmic disease, IgG4-related disease, serum IgG4, corticosteroids, balloon dacryocystoplasty, monocanalicular intubation, Masterka tube, nasolacrimal duct obstruction, silicone tube intubation, circadian IOP fluctuation, contact lens sensor, ripasudil, achromatopsia, cone, low vision aids, quality of life, personalised ophthalmology, Research and information: general, Biology, life sciences

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/114000
https://mdpi.com/books/pdfview/book/7845

Additive Intraocular Pressure Lowering Effects of Ripasudil in Patients with Primary Open Angle Glaucoma and Ocular Hypertension

Authors: Asma Jabeen, Ashok K Sharma, Hans Raj Sharma

Source: JK Science, Vol 26, Iss 1 (2024)

Subject Terms: Ripasudil, ROCK Inhibitors, Glaucoma, Ocular Hypertension, Medicine (General), R5-920, Internal medicine, RC31-1245

File Description: electronic resource

Relation: https://journal.jkscience.org/index.php/JK-Science/article/view/237; https://doaj.org/toc/0972-1177

Access URL: https://doaj.org/article/c01a95152fc94ab4973e990351f56082

Role of ripasudil as an adjunct treatment in the management of pseudoexfoliative glaucoma

Authors: Sumita Mohapatra, Subhodeep Thakur, Bijnya B Panda, Priti Das

Source: Indian Journal of Ophthalmology, Vol 71, Iss 7, Pp 2756-2759 (2023)

Subject Terms: intraocular pressure, pseudoexfoliative glaucoma, rho kinase inhibitor, ripasudil, rock inhibitor, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=7;spage=2756;epage=2759;aulast=Mohapatra; https://doaj.org/toc/0301-4738; https://doaj.org/toc/1998-3689

Access URL: https://doaj.org/article/7c78ef60e13d49cf891a8834bffbab41

Recent Clinical Research on Glaucoma

Contributors: Garcia-Medina, Jose Javier, Pinazo-Duran, Maria Dolores

Subject Terms: ripasudil, suture trabeculotomy ab interno, Schlemm’s canal incision, aqueous outflow, open-angle glaucoma, glaucoma, inflammation, oxidative stress, phenotype, polymorphism, susceptibility, intraocular pressure, ocular inflammation, cornea biomechanics, Corvis® ST, subclinical keratoconus, ocular hypertension, tears, miRNAs, next generation sequencing, biomarkers, genes, signaling pathways, apoptosis, neurodegeneration, glaucoma suspect, lamina cribrosa, optical coherence tomography angiography, peripapillary vessel density, OCTA, vessel density, disc, peripapillary, NTG, BRVO, corneal hysteresis, corneal biomechanics, ocular biomarkers, deep learning, perimetry, optic nerve, obesity, risk factor, young adults, multifocal visual evoked potentials, mfVEP, physical exercise, sport, acrobatic gymnastics, baseline intraocular pressure, central corneal thickness, ocular health, tumbling skills, hand balance, cytokines, BDNF, VEGF, fractalkine, microglia, saffron, crocin, retinal glial cells, microperimetry, OCT, macula, structure, function, correlation, retina, inner, outer, macular segmentation, optical coherence tomography-angiography, vascular density, blood flow, biomarker, myopia, Medicine and Nursing

File Description: image/jpeg

Access URL: https://directory.doabooks.org/handle/20.500.12854/81034
https://mdpi.com/books/pdfview/book/5376

Effect of the rho-kinase inhibitor ripasudil in needling with mitomycin C for the failure of filtering bleb after trabeculectomy: a cross-sectional study

Authors: Yu Mizuno, Naoki Okada, Hiromitsu Onoe, Kana Tokumo, Hideaki Okumichi, Kazuyuki Hirooka, Yoshiaki Kiuchi

Source: BMC Ophthalmology, Vol 22, Iss 1, Pp 1-8 (2022)

Subject Terms: Needling, Ripasudil, Rho-associated protein kinase inhibitor, Trabeculectomy, Glaucoma, Mitomycin C, Ophthalmology, RE1-994

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2415

Access URL: https://doaj.org/article/2402732827be4ec88a03ea527e0a6cf9

A multicenter phase II study on the safety of rho-kinase inhibitor (ripasudil) with needling for the patients after trabeculectomy

Authors: Yu Mizuno, Kaori Komatsu, Kana Tokumo, Naoki Okada, Hiromitsu Onoe, Hideaki Okumichi, Kazuyuki Hirooka, Yukiko Miura, Yoshiaki Kiuchi

Source: Contemporary Clinical Trials Communications, Vol 33, Iss , Pp 101160- (2023)

Subject Terms: Glaucoma, Trabeculectomy, Needling, A rho-associated protein kinase inhibitor, Ripasudil, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2451865423001060; https://doaj.org/toc/2451-8654

Access URL: https://doaj.org/article/d3ddb02e6836432d94568db18fba45d5

Effectiveness of Ripasudil, a Rho-Associated Coiled/Coil-Containing Protein Kinase Inhibitor, in Improving Retinoschisis and Cystic-Like Foveal Cavities in Eyes with X-Linked Retinoschisis

Authors: Hitomi Suimon, Masahiko Sugimoto, Hisashi Matsubara, Mineo Kondo

Source: Case Reports in Ophthalmology, Vol 11, Iss 2, Pp 411-417 (2020)

Subject Terms: cystic-like foveal cavities, retinoschisis, rho-associated coiled/coil-containing protein kinase inhibitor, ripasudil hydrochloride hydrate, x-linked retinoschisis, Ophthalmology, RE1-994

File Description: electronic resource

Relation: https://www.karger.com/Article/FullText/509261; https://doaj.org/toc/1663-2699

Access URL: https://doaj.org/article/f5dabe123b4c4c8d8b9ed3ef39fdfa7d

Safety and efficacy of ripasudil in Japanese patients with glaucoma or ocular hypertension: 12-month interim analysis of ROCK-J, a post-marketing surveillance study

Authors: Hidenobu Tanihara, Takahiko Kakuda, Tetsuro Sano, Takashi Kanno, Ryoji Gunji

Source: BMC Ophthalmology, Vol 20, Iss 1, Pp 1-11 (2020)

Subject Terms: Efficacy, Glaucoma, Intraocular pressure, Ripasudil, ROCK inhibitor, Safety, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12886-020-01490-1; https://doaj.org/toc/1471-2415

Access URL: https://doaj.org/article/c8929445c45844e58800be16fdc53139

Ripasudil Hydrochloride Hydrate in the Treatment of Glaucoma: Safety, Efficacy, and Patient Selection

Authors: Kusuhara S, Nakamura M

Source: Clinical Ophthalmology, Vol Volume 14, Pp 1229-1236 (2020)

Subject Terms: ripasudil, glaucoma, intraocular pressure, efficacy, safety, Ophthalmology, RE1-994

File Description: electronic resource

Relation: https://www.dovepress.com/ripasudil-hydrochloride-hydrate-in-the-treatment-of-glaucoma-safety-ef-peer-reviewed-article-OPTH; https://doaj.org/toc/1177-5483

Access URL: https://doaj.org/article/a8336d666cdd4c7b9e28933c1afc0e0a

Ripasudil alleviated the inflammation of RPE cells by targeting the miR-136-5p/ROCK/NLRP3 pathway

Authors: Zhao Gao, Qiang Li, Yunda Zhang, Xiaohong Gao, Haiyan Li, Zhigang Yuan

Source: BMC Ophthalmology, Vol 20, Iss 1, Pp 1-8 (2020)

Subject Terms: Ripasudil, ROCK1, ROCK2, miR-136-5p, RPE cells, NLRP3, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12886-020-01400-5; https://doaj.org/toc/1471-2415

Access URL: https://doaj.org/article/e5c09d5b434244a4a223789e69ec836a

Intraocular pressure-lowering effects of Ripasudil: a potential outcome marker for Trabeculotomy

Authors: Erina Goda, Kazuyuki Hirooka, Kazuhiko Mori, Yoshiaki Kiuchi

Source: BMC Ophthalmology, Vol 19, Iss 1, Pp 1-7 (2019)

Subject Terms: Ripasudil, Trabeculotomy, Glaucoma, Ophthalmology, RE1-994

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2415

Access URL: https://doaj.org/article/7972a49f336c4cab803839c8f4765327

Effects of 0.4% ripasudil hydrochloride hydrate on morphological changes in rabbit eyes

Authors: Bundit Limratchatamorn, Ken Asakawa, Kimiyo Mashimo, Shigekazu Uga, Hitoshi Ishikawa

Source: International Journal of Ophthalmology, Vol 12, Iss 10, Pp 1637-1642 (2019)

Subject Terms: ripasudil hydrochloride hydrate, actin filament, side effect, rabbit, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://www.ijo.cn/en_publish/2019/10/20191018.pdf; https://doaj.org/toc/2222-3959; https://doaj.org/toc/2227-4898

Access URL: https://doaj.org/article/6700678268db436c99020bc98b72bca2

Pan-ROCK and ROCK2 Inhibitors Affect Dexamethasone-Treated 2D- and 3D-Cultured Human Trabecular Meshwork (HTM) Cells in Opposite Manners

Authors: Megumi Watanabe, Yosuke Ida, Masato Furuhashi, Yuri Tsugeno, Fumihito Hikage, Hiroshi Ohguro

Source: Molecules, Vol 26, Iss 21, p 6382 (2021)

Subject Terms: 3D spheroid cultures, human trabecular meshwork (HTM), Rho-associated coiled-coil containing protein kinase (ROCK), ripasudil, KD025, dexamethasone, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/21/6382; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/87169559e7f3417f91f53c735e7bf2e0

Ocular hypotensive effects of a Rho-associated protein kinase inhibitor in rabbits

Authors: Kamaruddin MI, Nakamura-Shibasaki M, Mizuno Y, Kiuchi Y

Source: Clinical Ophthalmology, Vol Volume 11, Pp 591-597 (2017)

Subject Terms: ripasudil, timolol, pilocarpine, dorzolamide, intraocular pressure, rabbit, Ophthalmology, RE1-994

File Description: electronic resource

Relation: https://www.dovepress.com/ocular-hypotensive-effects-of-a-rho-associated-protein-kinase-inhibito-peer-reviewed-article-OPTH; https://doaj.org/toc/1177-5483

Access URL: https://doaj.org/article/50d8dcb4a78547c7bca71e46c83a9138

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