Efficacy and Safety of 4-Month Rifapentine-Based Tuberculosis Treatments in Persons with Diabetes

Authors: Ekaterina V. Kurbatova, William C. Whitworth, Lakshmi Praveena Peddareddy, Patrick P.J. Phillips, Nigel A. Scott, Kia E. Bryant, Rodney Dawson, Sandra Wagner Cardoso, Wadzanai Samaneka, Melissa Engle, Ziyaad Waja, Erin Sizemore, Wendy Carr, Kelly E. Dooley, Radojka Savic, Susan Swindells, Richard E. Chaisson, Susan E. Dorman, Payam Nahid, Nhung V. Nguyen

Source: Emerging Infectious Diseases, Vol 31, Iss 3, Pp 467-476 (2025)

Subject Terms: tuberculosis and other mycobacteria, diabetes, phase 3 clinical trial, rifapentine, moxifloxacin, antimicrobial resistance, Medicine, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://wwwnc.cdc.gov/eid/article/31/3/24-1634_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059

Access URL: https://doaj.org/article/741a0ed9af8348169ec0d113889d5597

In vitro activity of rifampicin, rifapentine and rifabutin in combination with their 25-deacetyl-metabolites against various Mycobacterium tuberculosis lineages

Authors: Charlotte Genestet, Chloé Bourg, Elisabeth Hodille, Olivier Bahuaud, Florence Ader, Sylvain Goutelle, Oana Dumitrescu, On behalf of the Lyon TB study group

Source: Annals of Clinical Microbiology and Antimicrobials, Vol 24, Iss 1, Pp 1-6 (2025)

Subject Terms: Mycobacterium tuberculosis, Rifamycin, Rifampicin, Rifapentine, Rifabutin, 25-deacetyl-metabolite, Therapeutics. Pharmacology, RM1-950, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/1476-0711

Access URL: https://doaj.org/article/67ff35ba899a4c76991842285d90dc08

Comparative study on the bioavailability and bioequivalence of rifapentine capsules in humans

Authors: Ying Qi, Pengfei Zhao

Source: Frontiers in Pharmacology, Vol 15 (2025)

Subject Terms: rifapentine, UPLC, bioavailability, bioequivalence, pharmacokinetics, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1463575/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/968c74c09e644dd0bdf6e5fe24b8f0b9

The Effect of Rifapentine and Rifampicin on Serum Voriconazole Levels Persist for 5 Days and 7 Days or More After Discontinuation in Tuberculosis Patients with Chronic Pulmonary Aspergillosis

Authors: Lu H, Mao Y, Zeng Y, Li P, Yan P, Shi Q, Liu L

Source: Infection and Drug Resistance, Vol Volume 17, Pp 2853-2862 (2024)

Subject Terms: voriconazole, rifampicin, rifapentine, serum concentration, discontinuation, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://www.dovepress.com/the-effect-of-rifapentine-and-rifampicin-on-serum-voriconazole-levels--peer-reviewed-fulltext-article-IDR; https://doaj.org/toc/1178-6973

Access URL: https://doaj.org/article/94c822d50dc0456eb6146d1405e5586f

First electrochemical investigation of the potent antibiotic rifapentine: Enhanced voltammetric detection using a boron-doped diamond electrode in tween-mediated measurements

Authors: Barzani, Hemn A.H. ^a, Ali, Hoshyar Saadi ^b, Yardım, Yavuz ^{c, ⁎}

Source: In Diamond & Related Materials February 2025 152

Latent TB treatment regimens in 2023: Wetmore TB clinic in New Orleans

Authors: Wolfe, Amy ^{a, ⁎}, Jadhav, Priyanka ^a, May, Amber ^b, Seymour, Shandrica ^a, Blanchard, Angela ^b, Ali, Juzar ^a

Source: In Journal of Clinical Tuberculosis and Other Mycobacterial Diseases May 2024 35

A mechanism study on the synergistic effects of rifapentine and fluconazole against fluconazole-resistant Candida albicans in vitro

Authors: Wang, Yulian ^a, He, Yufei ^a, Cai, Tongkai ^b, Lei, Zhongwei ^c, Lei, Wenzhi ^{d, ⁎⁎⁎}, Cao, Yongbing ^{b, ⁎⁎}, Wu, Jianhua ^{a, ⁎}

Source: In Heliyon 30 March 2024 10(6)

Leprosy: treatment, prevention, immune response and gene function

Authors: Xiang Li, Yun Ma, Guoli Li, Guangjie Jin, Li Xu, Yunhui Li, Pingmin Wei, Lianhua Zhang

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: leprosy, MDT, prophylaxis, rifapentine, immune cells, susceptibility gene, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1298749/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/2e73fa6788bf48efab4fd191d6515ded

The incorporation of the 3HP regimen for tuberculosis preventive treatment in the Brazilian health system: a secondary-database nationwide analysis

Authors: Luiz Villarinho Pereira Mendes, Anete Trajman, Mônica Rodrigues Campos, Marilena Cordeiro Dias Villela Correa, Claudia Garcia Serpa Osorio-de-Castro

Source: Frontiers in Medicine, Vol 10 (2024)

Subject Terms: Brazil, tuberculosis, latent tuberculosis, latent tuberculosis infection, drug utilization studies, Rifapentine, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2023.1289298/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/a77709e6e8ee4123bbb4be0f0f0ae9bf

Clinical tuberculosis

Authors: Meghji, Jamilah, Kon, Onn Min, Ainley, Adam

Source: In Medicine November 2023 51(11):768-773

Innovation and Evidence for Achieving TB Elimination in the Asia–Pacific Region

Contributors: DuCros, Philipp, Hussain, Hamidah, Viney, Kerri

Subject Terms: pediatric TB, verbal screening, contact tracing, resources, sputum, health promotion, operational research, indigenous population, multidrug-resistant tuberculosis, household contact, screening, TB diagnosis, yield, operations research, contacts, contact investigation, MDR-TB, public–private mix model, public–private partnership, missing cases, SORT IT, TB diagnostics, laboratory methods, case detection, Xpert Ultra, STR, Bangladesh regimen, tuberculosis, post-tuberculosis morbidity and mortality, TB preventive therapy, latent TB infection, Asia Pacific, rifapentine-isoniazid, incidence, household contacts tracing, End TB, sustainable development goals, South-East Asia, Western Pacific Region, national TB program, socio-economic determinants, diabetes mellitus, TB-DM, adverse drug reactions, unfavourable outcome, lymph node TB, bone TB, TB elimination, extrapulmonary tuberculosis, private sector, intermediary agency, referral, notification, Viet Nam, active case finding, community outreach, Indonesia, key population, innovation, TB REACH, community health workers, mobile X-ray screening, TB, chest X-ray, active TB case-finding, diagnostic algorithm, History, Social and ethical issues

File Description: image/jpeg

Access URL: https://directory.doabooks.org/handle/20.500.12854/79677
https://mdpi.com/books/pdfview/book/5062

Cost-effectiveness of 3-months isoniazid and rifapentine compared to 9-months isoniazid for latent tuberculosis infection: a systematic review

Authors: Wendy A. Lai, Kaitlyn Brethour, Olivia D’Silva, Richard E. Chaisson, Alice A. Zwerling

Source: BMC Public Health, Vol 22, Iss 1, Pp 1-11 (2022)

Subject Terms: Tuberculosis, Preventive treatment, Rifapentine, Isoniazid, Systematic review, Cost-effectiveness, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2458

Access URL: https://doaj.org/article/7bd780ad72664f1b891eee1a59a66fed

Development of tetracycline-modified nanoparticles for bone-targeted delivery of anti-tubercular drug

Authors: Qiuzhen Liang, Pengfei Zhang, Liang Zhang, Haopeng Luan, Xinxia Li, Haibin Xiang, Shuang Jing, Xinghua Song

Source: Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)

Subject Terms: rifapentine, bone targeting, nanoparticles, osteoarticular tuberculosis, anti-tubercular, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2023.1207520/full; https://doaj.org/toc/2296-4185

Access URL: https://doaj.org/article/3ab149019ce643288252acf16dab617f

Pharmacokinetics of isoniazid and rifapentine in young pediatric patients with latent tuberculosis infection

Authors: Weeraya Phaisal, Watsamon Jantarabenjakul, Noppadol Wacharachaisurapol, Monta Tawan, Thanyawee Puthanakit, Supeecha Wittayalertpanya, Pajaree Chariyavilaskul

Source: International Journal of Infectious Diseases, Vol 122, Iss , Pp 725-732 (2022)

Subject Terms: Isoniazid, Rifapentine, Pharmacokinetics, Pediatrics, Latent tuberculosis infection, Antituberculosis drugs, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1201971222004349; https://doaj.org/toc/1201-9712

Access URL: https://doaj.org/article/9d37e177caa5432bb9a17702d29355ba

Rifapentine and isoniazid for prevention of tuberculosis in people with diabetes (PROTID): protocol for a randomised controlled trial

Authors: Nyanda Elias Ntinginya, Lindsey te Brake, Issa Sabi, Nyasatu Chamba, Kajiru Kilonzo, Sweetness Laizer, Irene Andia-Biraro, Davis Kibirige, Andrew Peter Kyazze, Sandra Ninsiima, Julia A. Critchley, Renee Romeo, Josephine van de Maat, Willyhelmina Olomi, Lucy Mrema, David Magombola, Issakwisa Habakkuk Mwayula, Katrina Sharples, Philip C. Hill, Reinout van Crevel, On behalf of the PROTID Consortium

Source: Trials, Vol 23, Iss 1, Pp 1-16 (2022)

Subject Terms: Preventive treatment, Rifapentine, Isoniazid, Latent tuberculosis infection, Diabetes mellitus, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/e3d9b4ca6266415abb088fa7b7154c91

Effect of implementation of a 12-dose once-weekly treatment (3HP) in addition to standard regimens to prevent TB on completion rates: Interrupted time series design

Authors: Gonzalo G. Alvarez, Kathryn Sullivan, Christopher Pease, Deborah Van Dyk, Ranjeeta Mallick, Monica Taljaard, Jeremy M. Grimshaw, Kanchana Amaratunga, Crystal Allen, Kaitlyn Brethour, Sunita Mulpuru, Smita Pakhale, Shawn D. Aaron, D. William Cameron, Hannah Alsdurf, Charles Hui, Alice A. Zwerling

Source: International Journal of Infectious Diseases, Vol 117, Iss , Pp 222-229 (2022)

Subject Terms: Tuberculosis preventive treatment (TPT), Latent tuberculosis infection (LTBI), Rifapentine, Isoniazid, Prevention, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1201971222000728; https://doaj.org/toc/1201-9712

Access URL: https://doaj.org/article/151ef86f2dcc4501938270e3e1b1036d

Evaluation of drug-drug interaction between rilpivirine and rifapentine using PBPK modelling

Authors: Sandra Grañana-Castillo, Maiara Camotti Montanha, Rachel Bearon, Saye Khoo, Marco Siccardi

Source: Frontiers in Pharmacology, Vol 13 (2022)

Subject Terms: drug interaction (DI), PBPK, antiretroviral therapy, tuberculosis, rilpivirine, rifapentine, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.1076266/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/daaf3f7d3f2b42628b11fd58a9e08d20

An observational study on prevalence of latent tuberculosis infection and outcome of 3HP treatment in patients under hemodialysis in Taiwan

Authors: Chien-Hsing Wu, Hsuan-An Su, Chia-An Chou, Jien-Wei Liu, Chien-Te Lee, Lo-Hsin Dai, Chih-Chao Yang

Source: Journal of the Formosan Medical Association, Vol 120, Iss 6, Pp 1350-1360 (2021)

Subject Terms: 12-Week weekly rifapentine plus isoniazid (3HP), End-stage renal disease (ESRD), Hemodialysis, Interferon-gamma release assay (IGRA), Latent tuberculosis infection (LTBI), Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S092966462030468X; https://doaj.org/toc/0929-6646

Access URL: https://doaj.org/article/45202351483a447badcc90c69ffe7ce6

Rifapentine Polylactic Acid Sustained-Release Microsphere Complex for Spinal Tuberculosis Therapy: Preparation, in vitro and in vivo Studies

Authors: Wang Z, Maimaitiaili A, Wang T, Song X

Source: Infection and Drug Resistance, Vol Volume 14, Pp 1781-1794 (2021)

Subject Terms: spinal tuberculosis, sustained-release microsphere, antibiotics-loaded bone composite scaffold, rifapentine, tissue engineering, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://www.dovepress.com/rifapentine-polylactic-acid-sustained-release-microsphere-complex-for--peer-reviewed-fulltext-article-IDR; https://doaj.org/toc/1178-6973

Access URL: https://doaj.org/article/a62a9fbbe7624936b53e6817a0dcb15b

Determinants of Drug-Induced Hepatotoxicity Among Patients with Human Immunodeficiency Virus Taking a High Dose of Rifapentine Plus Isoniazid Drugs at the All Africa Leprosy Tuberculosis Rehabilitation and Training Center in Addis Ababa, Ethiopia

Authors: Lisanwork Arage L, Deybasso HA, Yilma Gebremichael D, Gintamo Nuramo B, Negash Mekuria Z

Source: HIV/AIDS: Research and Palliative Care, Vol Volume 13, Pp 307-314 (2021)

Subject Terms: isoniazid and rifapentine, tpt, hepatotoxicity, hiv patients, ethiopia, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.dovepress.com/determinants-of-drug-induced-hepatotoxicity-among-patients-with-human--peer-reviewed-article-HIV; https://doaj.org/toc/1179-1373

Access URL: https://doaj.org/article/7b31f9fc17c041ea8d0b5fbc9cb8f96c