Dual regulation of the levels and function of Start transcriptional repressors drives G1 arrest in response to cell wall stress.

Authors: Spiridon-Bodi, Mihai¹ (AUTHOR), Ros-Carrero, Cristina¹ (AUTHOR), Igual, J. Carlos¹ (AUTHOR), Gomar-Alba, Mercè¹ (AUTHOR) merce.gomar@uv.es

Source: Cell Communication & Signaling. 1/16/2025, Vol. 23 Issue 1, p1-18. 18p.

Subject Terms: *RETINOBLASTOMA protein, *CELL cycle, *CHIMERIC proteins, *CYTOLOGY, *LIFE sciences

Next Generation Sequencing and Structural Identification of retinoblastoma data Analysis.

Authors: Venkateswaran, T. V.^1,2, Kumari, Uma^1,2 uma27910@gmail.com

Source: European Journal of Cardiovascular Medicine. 2024, Vol. 14 Issue 4, p590-597. 8p.

Subject Terms: *NUCLEOTIDE sequencing, *RETINOBLASTOMA protein, *EYE cancer, *GENE expression, *PROTEIN structure, *PAPILLOMAVIRUSES

Probing the Effects of Retinoblastoma Binding Protein 6 (RBBP6) Knockdown on the Sensitivity of Cisplatin in Cervical Cancer Cells.

Authors: Mehta, Harshini¹ (AUTHOR) u16025483@tuks.co.za, Ambele, Melvin Anyasi^2,3 (AUTHOR) melvin.ambele@up.ac.za, Mokgautsi, Ntlotlang¹ (AUTHOR) u23040743@tuks.co.za, Moela, Pontsho¹ (AUTHOR) pontsho.moela@up.ac.za

Source: Cells (2073-4409). Apr2024, Vol. 13 Issue 8, p700. 19p.

Subject Terms: *RETINOBLASTOMA protein, *CISPLATIN, *CARRIER proteins, *CANCER cells, *CERVICAL cancer, *P53 antioncogene

Methylation of KSHV vCyclin by PRMT5 contributes to cell cycle progression and cell proliferation.

Authors: Niu, Danping¹, Ma, Yuanming¹, Ren, Pengyu¹, Chang, Sijia¹, Li, Chenhui¹, Jiang, Yong¹, Han, Chunyan¹, Lan, Ke^1,2,3, klan@whu.edu.cn

Source: PLoS Pathogens; 9/10/2024, Vol. 20 Issue 9, p1-30, 30p

Pharmacological induction of translational readthrough of nonsense mutations in the retinoblastoma (RB1) gene.

Authors: Palomar-Siles, Mireia¹ (AUTHOR), Yurevych, Viktor¹ (AUTHOR), Bykov, Vladimir J. N.¹ (AUTHOR), Wiman, Klas G.¹ (AUTHOR) Klas.Wiman@ki.se

Source: PLoS ONE. 11/2/2023, Vol. 18 Issue 11, p1-13. 13p.

Subject Terms: *SOMATIC mutation, *RETINOBLASTOMA protein, *TUMOR suppressor genes, *RETINOBLASTOMA, *NONSENSE mutation, *UBIQUITIN ligases, *BREAST, *UBIQUITINATION

RBBP6‐Mediated ERRα Degradation Contributes to Mitochondrial Injury in Renal Tubular Cells in Diabetic Kidney Disease.

Authors: Hu, Hongtu^1,2,3 (AUTHOR), Hu, Jijia^1,2 (AUTHOR), Chen, Zhaowei^1,2 (AUTHOR), Yang, Keju⁴ (AUTHOR), Zhu, Zijing^1,2 (AUTHOR), Hao, Yiqun^1,2 (AUTHOR), Zhang, Zongwei^1,2 (AUTHOR), Li, Weiwei^1,2 (AUTHOR), Peng, Zhuan^1,2 (AUTHOR), Cao, Yun⁵ (AUTHOR), Sun, Xiaoling⁶ (AUTHOR), Zhang, Fangcheng⁶ (AUTHOR), Chi, Qingjia⁷ (AUTHOR), Ding, Guohua^1,2 (AUTHOR) ghxding@whu.edu.cn, Liang, Wei^1,2 (AUTHOR) dr.liangwei@whu.edu.cn

Source: Advanced Science. 12/11/2024, Vol. 11 Issue 46, p1-17. 17p.

Subject Terms: *DIABETIC nephropathies, *RETINOBLASTOMA protein, *DISEASE progression, *GENE expression, *CARRIER proteins

Molecular analysis of HPV16 and HPV18 oncogenes in oral squamous cell carcinoma: Structural, transcriptomic and in vitro insights.

Authors: Hussain, Shazia Fathima Jaffer^1,2 (AUTHOR), Abullais, Shahabe Saquib³ (AUTHOR), Bottu, Kavitha² (AUTHOR), Thirumani, Logalakshmi⁴ (AUTHOR), Misbah, Iffath⁵ (AUTHOR), Madar, Inamul Hasan⁴ (AUTHOR), Alghamdi, Nuha S.⁶ (AUTHOR), Karobari, Mohmed Isaqali⁷ (AUTHOR) dr.isaq@gmail.com

Source: Oncology Letters. Mar2025, Vol. 29 Issue 3, pN.PAG-N.PAG. 1p.

Subject Terms: *HUMAN papillomavirus, *RETINOBLASTOMA protein, *GENE expression, *SQUAMOUS cell carcinoma, *GENE expression profiling

Expression, purification, and characterisation of the p53 binding domain of Retinoblastoma binding protein 6 (RBBP6).

Authors: Russell, Bonnie L.^1,2 (AUTHOR), Ntwasa, Monde¹ (AUTHOR) ntwasmm@unisa.ac.za

Source: PLoS ONE. 2/10/2023, Vol. 18 Issue 2, p1-22. 22p.

Subject Terms: *RETINOBLASTOMA protein, *CARRIER proteins, *BACTERIAL cells, *DRUG target, *EMBRYOLOGY, *P53 protein

Epstein-Barr virus replication within differentiated epithelia requires pRb sequestration of activator E2F transcription factors.

Authors: Schaal, Danielle L.^1,2,3, Amucheazi, Akajiugo A.¹, Jones, Sarah C.¹, Nkadi, Ebubechukwu H.^1,2,3, Scott, Rona S.^1,2,3 rona.scott@lsuhs.edu

Source: Journal of Virology. Oct2024, Vol. 98 Issue 10, p1-28. 28p.

Subject Terms: *HUMAN papillomavirus, *RETINOBLASTOMA protein, *DNA replication, *SQUAMOUS cell carcinoma, *GENE expression, *OROPHARYNX

Lack of Retinoblastoma Protein Shifts Tumor Metabolism from Glycolysis to OXPHOS and Allows the Use of Alternate Fuels.

Authors: Suresh Babu, Vishnu^1,2 (AUTHOR), Dudeja, Gagan³ (AUTHOR), SA, Deepak⁴ (AUTHOR), Bisht, Anadi¹ (AUTHOR), Shetty, Rohit¹ (AUTHOR), Heymans, Stephane^2,5 (AUTHOR) stephane.heymans@mumc.nl, Guha, Nilanjan⁴ (AUTHOR) stephane.heymans@mumc.nl, Ghosh, Arkasubhra¹ (AUTHOR) stephane.heymans@mumc.nl

Source: Cells (2073-4409). Oct2022, Vol. 11 Issue 20, p3182-N.PAG. 15p.

Subject Terms: *RETINOBLASTOMA protein, *TUMOR proteins, *GLYCOLYSIS, *FATTY acid oxidation, *METABOLISM, *GLUTAMINE synthetase, *GLUTAMINE, *NAD (Coenzyme)

CDK4/6 initiates Rb inactivation and CDK2 activity coordinates cell-cycle commitment and G1/S transition.

Authors: Kim, Sungsoo¹ (AUTHOR), Leong, Alessandra¹ (AUTHOR), Kim, Minah^1,2 (AUTHOR) mk4242@cumc.columbia.edu, Yang, Hee Won^1,2 (AUTHOR) hy2602@cumc.columbia.edu

Source: Scientific Reports. 10/7/2022, Vol. 12 Issue 1, p1-13. 13p.

Subject Terms: *CYCLIN-dependent kinases, *RETINOBLASTOMA protein, *DNA replication, *CELL cycle, *CYCLINS

Androgen-Induced MIG6 Regulates Phosphorylation of Retinoblastoma Protein and AKT to Counteract Non-Genomic AR Signaling in Prostate Cancer Cells.

Authors: Schomann, Tim¹ (AUTHOR) timmeeh@gmx.de, Mirzakhani, Kimia¹ (AUTHOR) kimiamirzakhani@rocketmail.com, Kallenbach, Julia¹ (AUTHOR) julia.kallenbach@uni-jena.de, Lu, Jing² (AUTHOR) jing.lu@leibniz-fli.de, Rasa, Seyed Mohammad Mahdi² (AUTHOR) mahdi.rasa@leibniz-fli.de, Neri, Francesco² (AUTHOR) francesco.neri@leibniz-fli.de, Baniahmad, Aria¹ (AUTHOR) aria.baniahmad@med.uni-jena.de

Source: Biomolecules (2218-273X). Aug2022, Vol. 12 Issue 8, p1048. 13p.

Subject Terms: *RETINOBLASTOMA protein, *PROSTATE cancer, *CELLULAR aging, *ANDROGEN receptors, *CANCER cells, *PHOSPHORYLATION

Reciprocal Regulation between lncRNA ANRIL and p15 in Steroid-Induced Glaucoma.

Authors: Wan, Peixing^1,2 (AUTHOR) wanpeixing@gzzoc.com, Huang, Siyu¹ (AUTHOR) siyuh5565@gmail.com, Luo, Yanting¹ (AUTHOR) luoyanting310@gmail.com, Deng, Caibin¹ (AUTHOR) dengcaibin928@gmail.com, Zhou, Jiajian³ (AUTHOR) zhoujj2013@smu.edu.cn, Long, Erping^1,4 (AUTHOR) longerping@gzzoc.com, Zhuo, Yehong¹ (AUTHOR) longerping@gzzoc.com

Source: Cells (2073-4409). May2022, Vol. 11 Issue 9, pN.PAG-N.PAG. 21p.

Subject Terms: *RNA regulation, *RETINOBLASTOMA protein, *VISION disorders, *GLAUCOMA, *INTRAOCULAR pressure, *CELLULAR aging

BRAF-Mutated Melanoma Cell Lines Develop Distinct Molecular Signatures After Prolonged Exposure to AZ628 or Dabrafenib: Potential Benefits of the Antiretroviral Treatments Cabotegravir or Doravirine on BRAF-Inhibitor-Resistant Cells.

Authors: Zanrè, Valentina¹ (AUTHOR) valentina.zanre@univr.it, Bellinato, Francesco² (AUTHOR) francesco.bellinato@univr.it, Cardile, Alessia¹ (AUTHOR), Passarini, Carlotta¹ (AUTHOR), Di Bella, Stefano³ (AUTHOR) sdibella@units.it, Menegazzi, Marta¹ (AUTHOR) marta.menegazzi@univr.it

Source: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p11939. 21p.

Subject Terms: *CELL cycle regulation, *HUMAN endogenous retroviruses, *RETINOBLASTOMA protein, *ANTIRETROVIRAL agents, *CELL division, *BRAF genes

CDK6-Dependent, CDK4-Independent Synovial Hyperplasia in Arthritic Mice and Tumor Necrosis Factor-α-Induced Proliferation of Synovial Fibroblasts.

Authors: Komatsu, Rie, Fujii, Ryoji, Ogasawara, Toru, Suzuki-Takahashi, Yuki, Chen, Sandy, Sugishita, Yodo, Niki, Hisateru, Yudoh, Kazuo

Source: International Journal of Molecular Sciences; Feb2025, Vol. 26 Issue 3, p1151, 12p

Subject Terms: SMALL interfering RNA, GENE expression, COLLAGEN-induced arthritis, RETINOBLASTOMA protein, CYCLIN-dependent kinase inhibitors

Patterns in the tapestry of chromatin-bound RB.

Authors: Sanidas, Ioannis¹ (AUTHOR), Lawrence, Michael S.^1,2 (AUTHOR), Dyson, Nicholas J.¹ (AUTHOR) ndyson@mgh.harvard.edu

Source: Trends in Cell Biology. Apr2024, Vol. 34 Issue 4, p288-298. 11p.

Subject Terms: *RETINOBLASTOMA protein, *CELL cycle, *TAPESTRY, *ANIMAL development, *CELL proliferation, *EPIGENOMICS

Epigenetic inactivation of DNA repair genes as promising prognostic and predictive biomarkers in urothelial bladder carcinoma patients.

Authors: Mohanad, Marwa¹, marwamohanad@gmail.com, Yousef, Hend F.², Bahnassy, Abeer A.²

Source: Molecular Genetics & Genomics; Nov2022, Vol. 297 Issue 6, p1671-1687, 17p

CVB3 VP1 interacts with MAT1 to inhibit cell proliferation by interfering with Cdk-activating kinase complex activity in CVB3-induced acute pancreatitis.

Authors: Zhang, Hongxia^1,2 (AUTHOR), Zeng, Lingbing¹ (AUTHOR), Liu, Qiong² (AUTHOR), Jin, Guilin³ (AUTHOR), Zhang, Jieyu⁴ (AUTHOR), Li, Zengbin² (AUTHOR), Xu, Yilian² (AUTHOR), Tian, Huizhen² (AUTHOR), Deng, Shanshan² (AUTHOR), Shi, Qiaofa² (AUTHOR), Huang, Xiaotian^1,2 (AUTHOR) xthuang@ncu.edu.cn

Source: PLoS Pathogens. 2/8/2021, Vol. 17 Issue 2, p1-25. 25p.

Subject Terms: *CELL proliferation, *RETINOBLASTOMA protein, *PANCREATITIS, *CAPSIDS, *CONFOCAL microscopy, *PROTEIN-protein interactions

Programmed cell death protein 1/programmed death ligand 1 but not HER2 is a potential therapeutic target in gastric neuroendocrine carcinoma.

Authors: Yamashita, Satoshi^1,2 (AUTHOR), Abe, Hiroyuki¹ (AUTHOR), Kunita, Akiko¹ (AUTHOR), Yamashita, Hiroharu² (AUTHOR), Seto, Yasuyuki² (AUTHOR), Ushiku, Tetsuo¹ (AUTHOR) usikut-tky@umin.ac.jp

Source: Histopathology. Feb2021, Vol. 78 Issue 3, p381-391. 11p.

Subject Terms: *PROGRAMMED cell death 1 receptors, *RETINOBLASTOMA protein, *PROGRAMMED death-ligand 1, *CARCINOMA

The NSD2/WHSC1/MMSET methyltransferase prevents cellular senescence‐associated epigenomic remodeling.

Authors: Tanaka, Hiroshi¹ (AUTHOR), Igata, Tomoka¹ (AUTHOR), Etoh, Kan¹ (AUTHOR), Koga, Tomoaki¹ (AUTHOR), Takebayashi, Shin‐ichiro¹ (AUTHOR), Nakao, Mitsuyoshi^1,2 (AUTHOR) mitnakao@kumamoto-u.ac.jp

Source: Aging Cell. Jul2020, Vol. 19 Issue 7, p1-12. 12p.

Subject Terms: *EPIGENOMICS, *RETINOBLASTOMA protein, *OXIDATIVE phosphorylation, *CELL cycle, *CANCER cells, *CELL lines