Cost analysis comparing guideline-oriented biopsychosocial management to usual care for low-back pain: a cluster-randomized trial in occupational health primary care

Authors: Maija Paukkunen, Jaro Karppinen, Birgitta Öberg, Leena Ala-Mursula, Eveliina Heikkala, Katja Ryynänen, Riikka Holopainen, Samuel Booth, Neill Booth, Allan Abbott

Source: Scandinavian Journal of Work, Environment & Health, Vol 51, Iss 3, Pp 201-213 (2025)

Subject Terms: low-back pain, occupational health, screening, occupational health service, health services research, return to work, pain, workability, resource, cluster-randomized trial, implementation research, risk stratification, örebro musculoskeletal pain screening questionnaire, cost analysis, biopsychosocial management, occupational health primary care, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://www.sjweh.fi/article/4212; https://doaj.org/toc/0355-3140; https://doaj.org/toc/1795-990X

Access URL: https://doaj.org/article/dff5516bcf5d43fb83c69a40a65a3368

Statin Therapy in Early Breast Cancer: The MASTER Trial; A Randomized Phase III, Placebo-Controlled Comparison of Standard (Neo)Adjuvant Therapy Plus Atorvastatin versus Standard (Neo)Adjuvant Therapy Plus Placebo

Authors: Borgquist S, Jensen MB, Bendorff CL, Christiansen P, Offersen BV, Kodahl AR, Ewertz M, Jensen AB, Ahern TP, Cronin-Fenton D, Ejlertsen B

Source: Clinical Epidemiology, Vol Volume 17, Pp 409-419 (2025)

Subject Terms: statin, breast cancer, recurrence, cholesterol, endocrine therapy, randomized trial, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://www.dovepress.com/statin-therapy-in-early-breast-cancer-the-master-trial-a-randomized-ph-peer-reviewed-fulltext-article-CLEP; https://doaj.org/toc/1179-1349

Access URL: https://doaj.org/article/f41a702124654e80a813d431137e7d98

Efficacy and tolerability of low versus standard daily doses of antiseizure medications in newly diagnosed focal epilepsy. A multicenter, randomized, single‐blind, non‐inferiority trial (STANDLOW)

Authors: Giorgia Giussani, Elisa Bianchi, Edoardo Carlando, Jacopo Cosimo DiFrancesco, Payam Tabaee Damavandi, Francesco Pasini, Giulia Pederzoli, Stefania Filipponi, Alessandra Gaiani, Luca Massacesi, Eleonora Rosati, Ginevra Giovannelli, Teresa Anna Cantisani, Michela Cecconi, Rossella Papetti, Monica Brioschi, Francesco Aruta, Elio Clemente Agostoni, Francesco Paladin, Filippo Dainese, Marco Longoni, Bartolini Yerma, Sara Gasparini, Umberto Aguglia, Edoardo Ferlazzo, Roberto Cantello, Gionata Strigaro, Marta Maschio, Dario Benincasa, Angela La Neve, Giovanni Falcicchio, Alfonso Giordano, Lara Buttarelli, Gabriele Enia, Maurizio Leone, Carlo Ferrarese, Ettore Beghi, Simone Beretta

Source: Epilepsia Open, Vol 10, Iss 2, Pp 643-653 (2025)

Subject Terms: efficacy, focal epilepsy, low dose, monotherapy, newly‐diagnosed epilepsy, randomized trial, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2470-9239

Access URL: https://doaj.org/article/57fe670ec97943899946de1154f36ee0

Trusted health system implementation strategies to increase vaccination (TRUE SYNERGI): a stepped-wedge cluster randomized trial to reduce HPV-related cancers

Authors: Daisy Y. Morales-Campos, Prajakta Adsul, Yuanyuan Liang, Erin Donovan, Leticia R. Moczygemba, Jessica A. Kahn

Source: BMC Public Health, Vol 25, Iss 1, Pp 1-15 (2025)

Subject Terms: HPV vaccination, Latino/a, Implementation, Sustainability, Hybrid type 2 study, Stepped-wedge cluster randomized trial, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2458

Access URL: https://doaj.org/article/d434fb7180d14fa99704d44993cabaa3

Development and evaluation of a school-based bullying prevention program (Bullying&You): study protocol for a cluster randomized trial

Authors: Vanessa Jantzer, Franziska Neumayer, Stefan Lerch, Michael Kaess

Source: Trials, Vol 26, Iss 1, Pp 1-17 (2025)

Subject Terms: Bullying, Mental health, School, Prevention, Adolescents, Cluster randomized trial, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/8023605b7fdf416c99ecffc65fcc3e2b

Statistical analysis plan for the Robotic-Assisted Surgery and Kinematic ALignment in total knee arthroplasty (RASKAL) registry-nested randomized trial

Authors: Samuel J. MacDessi, Gregory C. Wernecke, Durga Bastiras, Khashayar Ghadirinejad, Dylan Harries, Kara Cashman, Emma Heath, Michelle Lorimer, Carl Holder, Ian A. Harris

Source: Bone & Joint Open, Vol 6, Iss 3, Pp 352-360 (2025)

Subject Terms: knee, robotic, kinematic, arthroplasty, statistical analysis, total knee arthroplasty (tka), knee injury and osteoarthritis outcome score, patient-reported outcome measures (proms), functional outcomes, randomized trial, prosthetic, cox proportional hazards models, soft-tissue, Orthopedic surgery, RD701-811

File Description: electronic resource

Relation: https://doaj.org/toc/2633-1462

Access URL: https://doaj.org/article/310b8429e18a44838d50f0b91db6390c

A double-blind randomized trial of hyperbaric oxygen for persistent symptoms after brain injury

Authors: Lindell K. Weaver, Rosemary Ziemnik, Kayla Deru, Antonietta A. Russo

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-18 (2025)

Subject Terms: Hyperbaric oxygen, Randomized trial, Brain injury, Traumatic brain injury, Carbon monoxide poisoning, Blinded, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/225d653d9144462cb2e4ebda96d4e213

One-year follow-up effects of the informed health choices secondary school intervention on students’ ability to think critically about health in Uganda: a cluster randomized trial

Authors: Ronald Ssenyonga, Andrew D. Oxman, Esther Nakyejwe, Faith Chesire, Michael Mugisha, Allen Nsangi, Matt Oxman, Christopher James Rose, Sarah E. Rosenbaum, Jenny Moberg, Margaret Kaseje, Laetitia Nyirazinyoye, Astrid Dahlgren, Simon Lewin, Nelson K. Sewankambo

Source: Trials, Vol 26, Iss 1, Pp 1-11 (2025)

Subject Terms: Critical thinking, Randomized trial, Critical health literacy, Secondary school, Teaching and learning resources, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/16ba8db39323449f8ea9f1feac449eba

Efficacy and safety of perioperative analgesia in PENG block for children undergoing hip surgery with developmental dysplasia: study protocol for a randomized, double-blinded, non-inferiority trial

Authors: Mingzhe Xu, Yi He, Zhi Li, Bin Du

Source: Trials, Vol 26, Iss 1, Pp 1-7 (2025)

Subject Terms: Perioperative analgesia, Pericapsular nerve group block, Developmental dysplasia, Hip surgery, Children, Randomized trial, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/85ff264efcbe4c9e8930b1265ea8ee64

Cost–Benefit Analysis of in vivo Reflectance Confocal Microscopy for Melanoma Diagnosis in a Real-World Clinical Setting

Authors: Bruno GM, Di Matteo S, Longo C, Stanganelli I, Farnetani F, Borsari S, Mazzoni L, Ciardo S, Raucci M, Magi S, Bassoli S, Spadafora M, Mandel VD, Casari A, Chester J, Kaleci S, Colombo GL, Pellacani G

Source: Risk Management and Healthcare Policy, Vol Volume 18, Pp 163-172 (2025)

Subject Terms: melanoma, skin cancer, diagnosis, non-invasive diagnosis, imaging techniques, skin imaging, reflectance confocal microscopy, dermatoscopy, dermoscopy, number needed to excise, follow-up, randomized trial., Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://www.dovepress.com/costbenefit-analysis-of-in-vivo-reflectance-confocal-microscopy-for-me-peer-reviewed-fulltext-article-RMHP; https://doaj.org/toc/1179-1594

Access URL: https://doaj.org/article/b6080052763f49a894e99fd7111f4221

Comparative study of the clinical efficacy of the first domestic bioanalogue of tocilizumab based on the results of a randomized clinical trial of phase III

Authors: E. V. Akatova, Yu. S. Bakhareva, O. V. Bugrova, I. B. Vinogradova, E. V. Gerasimova, Yu. E. Drevina, O. B. Ershova, E. V. Zonova, Yu. I. Ivanova, E. P. Ilivanova, M. M. Kostik, D. G. Krechikova, D. A. Kusevich, A. L. Maslyansky, A. D. Meshkov, N. S. Mosesova, K. A. Nagornova, D. V. Nosovich, S. A. Polyakova, T. A. Popova, E. A. Smolyarchuk, V. N. Sorotskaya, Yu. G. Shvarts, L. N. Shilova, M. S. Shostak, I. Yu. Yunonin, N. E. Akhtyamova-Givirovskaya, R. A. Khamitov, O. A. Markova, E. I. Zagoruiko, E. V. Zuev

Source: Современная ревматология, Vol 18, Iss 6, Pp 36-45 (2024)

Subject Terms: tocilizumab, rheumatoid arthritis, acr, das28, clinical disease activity index (cdai), simplified disease activity index (sdai), monoclonal antibody, interleukin-6, randomized trial, biosimilar, Medicine

File Description: electronic resource

Relation: https://mrj.ima-press.net/mrj/article/view/1664; https://doaj.org/toc/1996-7012; https://doaj.org/toc/2310-158X

Access URL: https://doaj.org/article/ddf4dd25d4f648f59e3aff2936550d6b

Standardized study performance, quality assurance, and quality control in a cluster-randomized trial: the Pneumococcal Vaccine Schedules trial

Authors: Isaac Osei, Benjamin Young, Golam Sarwar, Yekini A. Olatunji, Ilias Hossain, Babila G. Lobga, Baleng M. Wutor, Williams Adefila, Emmanuel Mendy, Banjo Adeshola, Yasir Shitu Isa, Yusuf A. Olawale, Keita M. Lamin, Ebrimah Nyimanta, Bubacarr Baldeh, Abdoullah Nyassi, Momodou M. Drammeh, Barjo Ousman, Minteh Molfa, Rasheed Salaudeen, Grant A. Mackenzie

Source: Trials, Vol 25, Iss 1, Pp 1-9 (2024)

Subject Terms: Quality assurance, Quality control, Cluster-randomized trial, Monitoring, Supervisory visits, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/77601153c63640b19c58d3d64462b74c

Enrolment patterns in a randomized controlled trial of probiotics in critically ill patients: a retrospective analysis of the PROSPECT trial

Authors: Alyson Takaoka, Jennie Johnstone, François Lauzier, Diane Heels-Ansdell, Megan Davis, Nicole Zytaruk, Erick Duan, Joanna Dionne, Lois Saunders, Yaseen M. Arabi, John Marshall, Lehana Thabane, France Clarke, Lori Hand, Marie-Helene Masse, Bram Rochwerg, Lauralyn McIntyre, Martin Girard, Andreas Freitag, Tim Karachi, Deborah J. Cook, For The PROSPECT Investigators, The Canadian Critical Care Trials Group

Source: Trials, Vol 25, Iss 1, Pp 1-9 (2024)

Subject Terms: Randomized trial, Critical illness, Enrolment, Screening, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/333261b09aba4dc58084c031d38f1151

Enhancing stroke response in school children: Efficacy of the HOBIT program - a cluster randomized trial

Authors: Ekaterina Volevach, Hana Maršálková, Robert Mikulik

Source: Preventive Medicine Reports, Vol 53, Iss , Pp 103049- (2025)

Subject Terms: Cluster randomized trial, School, Children, Intervention, Stroke awareness, Health education, Medicine

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211335525000889; https://doaj.org/toc/2211-3355

Access URL: https://doaj.org/article/948fd2e16b2546509331e1a950a21bcc

Efficacy and safety of transcutaneous electrical acupoint stimulation for preoperative anxiety in thoracoscopic surgery: a randomized controlled trial

Authors: Jie Zhang, Xindi Wu, Chenni Ju, Subinuer Kurexi, Xiaoxiao Zhou, Ke Wang, Tongyu Chen

Source: Frontiers in Medicine, Vol 12 (2025)

Subject Terms: electrical acupoint stimulation, preoperative anxiety, general anesthesia, video-assisted thoracoscopic surgery, randomized trial, peri-operative, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2025.1527993/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/dfbce087da5d41e5965efb17c3f18d9d

POST‐UK (Adjunctive Intra‐Arterial Urokinase After Successful Endovascular Thrombectomy in Patients With Large‐Vessel Occlusion Stroke): Study Protocol of a Multicenter, Prospective, Randomized, Open‐Label, Blinded‐End Point Trial

Authors: Chang Liu, Fengli Li, Jiaxing Song, Xu Xu, Jiacheng Huang, Changwei Guo, Weilin Kong, Jie Yang, Xiaolei Shi, Jinfu Ma, Shihai Yang, Zhixi Wang, Shitao Fan, Liu Xiang, Sun Wenzhe, Nizhen Yu, Chengsong Yue, Zhouzhou Peng, Linyu Li, Cheng Huang, Dahong Yang, Duolao Wang, Jeffrey Saver, Thanh N. Nguyen, Raul G. Nogueira, Yangmei Chen, Wenjie Zi

Source: Stroke: Vascular and Interventional Neurology, Vol 5, Iss 2 (2025)

Subject Terms: adjunctive therapy, endovascular thrombectomy, intra‐arterial urokinase, randomized trial, trial protocol, Neurology. Diseases of the nervous system, RC346-429, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2694-5746

Access URL: https://doaj.org/article/ef6d657d01714cd7b2b921c9251ca503

Effects of the Chinese traditional fitness practice Wuqinxi on balance improvement in older women with a history of falls: a randomized controlled trial

Authors: Yutao Jiang, Heng Liu

Source: Frontiers in Public Health, Vol 13 (2025)

Subject Terms: balance training, older adult health, fall risk reduction, gender-based interventions, randomized trial, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpubh.2025.1503309/full; https://doaj.org/toc/2296-2565

Access URL: https://doaj.org/article/60f300b610e1482997f075a7a9a64279

The analgesic effectiveness of auriculotherapy for acute postoperative pain: A systematic review and meta-analysis

Authors: Guilin Zhang, Guixing Xu, Yao Tang, Lingxue Zhang, Xi Chen, Xingyu Liang, Ling Zhao, Dehua Li

Source: Complementary Therapies in Medicine, Vol 88, Iss , Pp 103112- (2025)

Subject Terms: Acute postoperative pain, Auriculotherapy, Meta-analysis, Multimodal analgesia, Randomized trial, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0965229924001006; https://doaj.org/toc/0965-2299

Access URL: https://doaj.org/article/004cf1bf157641018776e599079cd774

Influenza vaccination in patients with acute heart failure (PANDA II): study protocol for a hospital-based, parallel-group, cluster randomized controlled trial in China

Authors: Yiqun Zhang, Rong Liu, Yangyang Zhao, Zhiyan Wang, Chi Wang, Qiang Li, Dorothy Han, Craig S. Anderson, Xin Du, Jianzeng Dong

Source: Trials, Vol 25, Iss 1, Pp 1-10 (2024)

Subject Terms: Influenza vaccine, Heart failure, Cluster randomized trial, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/a979185c22dd4699b18e22339ee100a1

Treatment of subclinical hyperthyroidism in patients older than 50 years: a randomized controlled study

Authors: Bernard Goichot, François Lefebvre, Stéphane Vinzio, Anne Cailleux, Jean-Marc Kuhn, Olivier Schneegans, Bodgan Catargi, Olivier Gilly, Philippe Baltzinger, Nicolas Meyer, Philippe Caron

Source: European Thyroid Journal, Vol 13, Iss 6, Pp 1-9 (2024)

Subject Terms: atrial fibrillation, elderly, quality of life, randomized trial, subclinical hyperthyroidism, symptoms, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://etj.bioscientifica.com/view/journals/etj/13/6/ETJ-24-0121.xml; https://doaj.org/toc/2235-0802

Access URL: https://doaj.org/article/4c1652b29fb3484b8432e9cd968e00d7