PI3K/AKT/mTOR Signaling Network in Human Health and Diseases

Contributors: Chamcheu, Jean Christopher, Bürger, Claudia, Huang, Shile

Subject Terms: hepatocellular cancer, HCC, LIHC, PDK1, PI3K/AKT/mTOR pathway, BX795, selective inhibitor, radiotherapy, radioresistance, combination therapy, stemness, DNA damage, galectin-1, upper urinary urothelial carcinoma, epithelial–mesenchymal transition, survival, phosphoinositide 3-kinases, focal adhesion kinase, mammalian target of rapamycin, ascorbic acid, oxidative stress, apoptosis, autophagic flux blockage, PI3K/Akt, corneal endothelial cells, PIK3CA, colorectal cancer, EGFR pathway, tumor heterogeneity, RSK, mTORC2, p90 ribosomal s6 kinase, nutrients, AGC kinases, MAPK/ERK, CCTβ, CCT/TRiC, chaperonin, starvation, metabolism, TFEB agonists, autophagy, lysosome, rapamycin, resveratrol, dihydroartemisinin, rhabdomyosarcoma, mTOR, AMPK, PTEN, raptor, muscle protein synthesis, GSI, AKT, SEA complex, GATOR complex, mTORC1 pathway, amino acid signaling, cancer, epilepsy, neurological disorders, JC polyomavirus, PML, astrocytes, SVGA cells, primary cells, PI3K, wortmannin, PI3K/Akt pathway, myocardial infarction, heart failure, left ventricular remodeling, diabetes, necroptosis, ferroptosis, pyroptosis, fibrosis, extracellular vesicles, PI3K/Akt/mTOR pathway, bone marrow mesenchymal stem cells, bone microvascular endothelial cells, breast cancer, AKT1, RNA-sequencing, transcriptome, emerging functions and targets, cancer therapeutics, psoriasis, inflammation, mTORC1, tuberous sclerosis complex, cytokines, cell penetrating peptide, cellular signaling, kinase, protein kinase B (AKT1), phosphoinositide-dependent kinase (PDK1), recombinant protein, trans-activator of transcription (TAT), Research and information: general, Biology, life sciences, Thermodynamics and heat

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Access URL: https://directory.doabooks.org/handle/20.500.12854/153061
https://mdpi.com/books/pdfview/book/10392

Gou Qi Zi inhibits proliferation and induces apoptosis through the PI3K/AKT1 signaling pathway in non-small cell lung cancer

Authors: Lingling Zhang, Yanju Gong, Lei Zhang, Bing Liang, Huan Xu, Wangming Hu, Zhong Jin, Xiao Wu, Xiongbin Chen, Min Li, Liangqin Shi, Yaping Shi, Mingjian Li, Yong Huang, Yong Wang, Lan Yang

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: traditional Chinese medicine (TCM), Gou Qi Zi (Lycium barbarum), non-small cell lung cancer (NSCLC), Network pharmacology, Molecular docking, Protein kinase B (AKT1), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.1034750/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/81370c2006604f4f8753441ca11bf0d8

Delivery of Active AKT1 to Human Cells

Authors: Tarana Siddika, Nileeka Balasuriya, Mallory I. Frederick, Peter Rozik, Ilka U. Heinemann, Patrick O’Donoghue

Source: Cells, Vol 11, Iss 23, p 3834 (2022)

Subject Terms: cell penetrating peptide, cellular signaling, kinase, protein kinase B (AKT1), phosphoinositide-dependent kinase (PDK1), recombinant protein, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/23/3834; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/c298f968b214421fa1429d174d9c4f93