Organic cation transporters 2: Structure, regulation, functions, and clinical implications

Authors: Ailabouni, Anoud, Prasad, Bhagwat ^∗

Source: In Drug Metabolism and Disposition March 2025 53(3)

Heterotropic allosteric modulation of CYP3A4 in vitro by progesterone: Evidence for improvement in prediction of time-dependent inhibition for macrolides

Authors: Rougée, Luc R.A. ^∗, Hegde, Pooja V., Shin, Kaitlin, Abraham, Trent L., Bell, Alec, Hall, Stephen D.

Source: In Drug Metabolism and Disposition January 2025 53(1)

PBPK-based translation from preclinical species to humans for the full-size IgG therapeutic efalizumab

Authors: Maria Franz, Ravi Kumar Jairam, Lars Kuepfer, Nina Hanke

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: efalizumab, raptiva, cross-species translation, physiologically based pharmacokinetic modeling (PBPK), monoclonal antibody (mAb), target mediated drug disposition (TMDD), Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1418870/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/584054ca9bd24dc6b481a8570bbae847

Evaluation of the Drug–Drug Interaction Potential of Cannabidiol Against UGT2B7-Mediated Morphine Metabolism Using Physiologically Based Pharmacokinetic Modeling

Authors: Shelby Coates, Keti Bardhi, Bhagwat Prasad, Philip Lazarus

Source: Pharmaceutics, Vol 16, Iss 12, p 1599 (2024)

Subject Terms: physiologically based pharmacokinetic modeling (PBPK), UDP-glucuronosyltransferase (UGT), cannabidiol, cannabinoid, morphine, IVIVE, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/16/12/1599; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/5c407eae9b7746d2a4a3f571660deeb7

Physiologically-Based Pharmacokinetic Modeling and In Vitro–In Vivo Correlation of TV-46000 (Risperidone LAI): Prediction from Dog to Human

Authors: David Bibi, Raphael Bilgraer, Lilach Steiner, Hussein Hallak

Source: Pharmaceutics, Vol 16, Iss 7, p 896 (2024)

Subject Terms: physiologically-based pharmacokinetic modeling (PBPK), in vitro–in vivo correlation (IVIVC), long-acting injectable (LAI), TV-46000, risperidone, schizophrenia, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/16/7/896; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/e6298492b68d4b7592574b3b7f693b17

Vinblastine pharmacokinetics in mouse, dog, and human in the context of a physiologically based model incorporating tissue‐specific drug binding, transport, and metabolism

Authors: Sandra Witta, Keagan P. Collins, Dominique A. Ramirez, Joshua D. Mannheimer, Luke A. Wittenburg, Daniel L. Gustafson

Source: Pharmacology Research & Perspectives, Vol 11, Iss 1, Pp n/a-n/a (2023)

Subject Terms: comparative oncology, physiologically‐based pharmacokinetic modeling (PBPK), vinblastine, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2052-1707

Access URL: https://doaj.org/article/61d9b71b4f14428898236b51eb463339

The emerging role of physiologically-based pharmacokinetic/biopharmaceutics modeling in formulation development

Authors: Cvijić Sandra, Ignjatović Jelisaveta, Parojčić Jelena, Ibrić Svetlana

Source: Arhiv za farmaciju, Vol 71, Iss 4, Pp 318-335 (2021)

Subject Terms: physiologically-based pharmacokinetic modeling (pbpk), physiologically-based biopharmaceutics modeling (pbbm), model informed drug development (midd), drug bioperformance, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2021/0004-19632104318C.pdf; https://doaj.org/toc/0004-1963; https://doaj.org/toc/2217-8767

Access URL: https://doaj.org/article/c821d7df8afc493597f1f37cce3ff794

In-Depth Analysis of Physiologically Based Pharmacokinetic (PBPK) Modeling Utilization in Different Application Fields Using Text Mining Tools

Authors: Aleksandra Krstevska, Jelena Đuriš, Svetlana Ibrić, Sandra Cvijić

Source: Pharmaceutics, Vol 15, Iss 1, p 107 (2022)

Subject Terms: physiologically based pharmacokinetic modeling (PBPK), physiologically based biopharmaceutics modeling (PBBM), text mining, topic modeling, modeling and simulations (M&S), Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/1/107; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/4cd4539a2dc24ab58b1c1584a92ae828

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